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Cutaneous melanoma
scientific article published in The Lancet
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instance of
scholarly article
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title
Cutaneous melanoma
(English)
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author
Alexander Eggermont
series ordinal
1
object named as
Alexander M M Eggermont
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author name string
Alan Spatz
series ordinal
2
0 references
Caroline Robert
series ordinal
3
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language of work or name
English
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publication date
1 March 2014
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published in
The Lancet
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volume
383
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issue
9919
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page(s)
816-27
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cites work
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A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma
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Sunbed use during adolescence and early adulthood is associated with increased risk of early-onset melanoma
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Cutaneous melanoma attributable to sunbed use: systematic review and meta-analysis
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Epidemiological evidence that UVA radiation is involved in the genesis of cutaneous melanoma
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based on heuristic
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Prognostic significance of mitotic rate in localized primary cutaneous melanoma: an analysis of patients in the multi-institutional American Joint Committee on Cancer melanoma staging database
1 reference
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Crossref
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7 January 2021
based on heuristic
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Quality of histopathological reporting on melanoma and influence of use of a synoptic template.
1 reference
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Crossref
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7 January 2021
based on heuristic
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Mutations of the BRAF gene in human cancer
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7 January 2021
based on heuristic
inferred from DOI database lookup
Genome-wide association study identifies three loci associated with melanoma risk
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic and morphologic features for melanoma classification
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Distinct sets of genetic alterations in melanoma
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
BRAF/NRAS mutation frequencies among primary tumors and metastases in patients with melanoma.
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Distinguishing Clinicopathologic Features of Patients with V600E and V600K BRAF-Mutant Metastatic Melanoma
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Incidence of BRAF p.Val600Glu and p.Val600Lys mutations in a consecutive series of 183 metastatic melanoma patients from a high incidence region
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Analytical performance of a real-time PCR-based assay for V600 mutations in the BRAF gene, used as the companion diagnostic test for the novel BRAF inhibitor vemurafenib in metastatic melanoma
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Immunohistochemistry is highly sensitive and specific for the detection of V600E BRAF mutation in melanoma.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
KIT gene mutations and copy number in melanoma subtypes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
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7 January 2021
based on heuristic
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KIT as a therapeutic target in metastatic melanoma
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
BRAF and c-kit gene copy number in mutation-positive malignant melanoma
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Human cutaneous melanoma; a review of NRAS and BRAF mutation frequencies in relation to histogenetic subclass and body site
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7 January 2021
based on heuristic
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Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
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Randomized adjuvant therapy trials in melanoma: surgical and systemic
1 reference
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Crossref
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7 January 2021
based on heuristic
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Sentinel-node biopsy or nodal observation in melanoma
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Sentinel node tumor burden according to the Rotterdam criteria is the most important prognostic factor for survival in melanoma patients: a multicenter study in 388 patients with positive sentinel nodes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Prognosis in patients with sentinel node-positive melanoma is accurately defined by the combined Rotterdam tumor load and Dewar topography criteria
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
The risk of in-transit melanoma metastasis depends on tumor biology and not the surgical approach to regional lymph nodes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rotterdam Criteria for sentinel node (SN) tumor burden and the accuracy of ultrasound (US)-guided fine-needle aspiration cytology (FNAC): can US-guided FNAC replace SN staging in patients with melanoma?
1 reference
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Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ultrasound morphology criteria predict metastatic disease of the sentinel nodes in patients with melanoma
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Surgery and radiotherapy in the treatment of cutaneous melanoma
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Safety and efficacy of isolated limb infusion with cytotoxic drugs in elderly patients with advanced locoregional melanoma
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
One hundred consecutive isolated limb perfusions with TNF-alpha and melphalan in melanoma patients with multiple in-transit metastases
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
20 years experience of TNF-based isolated limb perfusion for in-transit melanoma metastases: TNF dose matters
1 reference
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Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A phase 2 trial of complete resection for stage IV melanoma: results of Southwest Oncology Group Clinical Trial S9430
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High-dose interferon alfa-2b significantly prolongs relapse-free and overall survival compared with the GM2-KLH/QS-21 vaccine in patients with resected stage IIB-III melanoma: results of intergroup trial E1694/S9512/C509801
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Therapeutic vaccines in solid tumours: can they be harmful?
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of granulocyte/macrophage colony-stimulating factor on vaccination with an allogeneic whole-cell melanoma vaccine
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of granulocyte/macrophage colony-stimulating factor on circulating CD8+ and CD4+ T-cell responses to a multipeptide melanoma vaccine: outcome of a multicenter randomized trial
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selection of immunostimulant AS15 for active immunization with MAGE-A3 protein: results of a randomized phase II study of the European Organisation for Research and Treatment of Cancer Melanoma Group in Metastatic Melanoma
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Predictive gene signature in MAGE-A3 antigen-specific cancer immunotherapy.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Phase II clinical trial of a granulocyte-macrophage colony-stimulating factor-encoding, second-generation oncolytic herpesvirus in patients with unresectable metastatic melanoma
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Local and distant immunity induced by intralesional vaccination with an oncolytic herpes virus encoding GM-CSF in patients with stage IIIc and IV melanoma
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Does adjuvant interferon-alpha for high-risk melanoma provide a worthwhile benefit? A meta-analysis of the randomised trials
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interferon alpha adjuvant therapy in patients with high-risk melanoma: a systematic review and meta-analysis.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Adjuvant therapy with pegylated interferon alfa-2b versus observation alone in resected stage III melanoma: final results of EORTC 18991, a randomised phase III trial
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Post-surgery adjuvant therapy with intermediate doses of interferon alfa 2b versus observation in patients with stage IIb/III melanoma (EORTC 18952): randomised controlled trial
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Multivariate analysis of prognostic factors among 2,313 patients with stage III melanoma: comparison of nodal micrometastases versus macrometastases
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gene Expression Profiling of Primary Cutaneous Melanoma and Clinical Outcome
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Long-term protective effect of mature DC-LAMP+ dendritic cell accumulation in sentinel lymph nodes containing micrometastatic melanoma
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interobserver reproducibility of ulceration assessment in primary cutaneous melanomas.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ulceration and stage are predictive of interferon efficacy in melanoma: results of the phase III adjuvant trials EORTC 18952 and EORTC 18991.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two different durations of adjuvant therapy with intermediate-dose interferon alfa-2b in patients with high-risk melanoma (Nordic IFN trial): a randomised phase 3 trial
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Long-term results of the randomized phase III trial EORTC 18991 of adjuvant therapy with pegylated interferon alfa-2b versus observation in resected stage III melanoma
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multiplex analysis of serum cytokines in melanoma patients treated with interferon-alpha2b.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prognostic significance of autoimmunity during treatment of melanoma with interferon
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Autoimmune antibodies and recurrence-free interval in melanoma patients treated with adjuvant interferon
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Phase III trial comparing adjuvant treatment with pegylated interferon Alfa-2b versus observation: prognostic significance of autoantibodies--EORTC 18991.
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Anti-CTLA-4 antibody adjuvant therapy in melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Extended dose ipilimumab with a peptide vaccine: immune correlates associated with clinical benefit in patients with resected high-risk stage IIIc/IV melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Meta-analysis of phase II cooperative group trials in metastatic stage IV melanoma to determine progression-free and overall survival benchmarks for future phase II trials
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Re-evaluating the role of dacarbazine in metastatic melanoma: what have we learned in 30 years?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fotemustine compared with dacarbazine in patients with disseminated malignant melanoma: a phase III study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Improved survival with vemurafenib in melanoma with BRAF V600E mutation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Clinical development of the anti-CTLA-4 antibody tremelimumab
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phase I/II study of ipilimumab for patients with metastatic melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phase III randomized clinical trial comparing tremelimumab with standard-of-care chemotherapy in patients with advanced melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytotoxic T-lymphocyte-associated antigen 4 antibody-induced colitis and its management with infliximab.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteria
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Improved endpoints for cancer immunotherapy trials
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ipilimumab monotherapy in patients with pretreated advanced melanoma: a randomised, double-blind, multicentre, phase 2, dose-ranging study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anti-cytotoxic T-lymphocyte antigen-4.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Single-institution experience with ipilimumab in advanced melanoma patients in the compassionate use setting: lymphocyte count after 2 doses correlates with survival
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ctla-4 blockade confers lymphocyte resistance to regulatory T-cells in advanced melanoma: surrogate marker of efficacy of tremelimumab?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunogenic and tolerogenic cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunologic correlates of the abscopal effect in a patient with melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Safety and Tumor Responses with Lambrolizumab (Anti–PD-1) in Melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nivolumab plus ipilimumab in advanced melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Adoptive cell transfer: a clinical path to effective cancer immunotherapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A dual role for genetically modified lymphocytes in cancer immunotherapy.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Adoptive immunotherapy for cancer: harnessing the T cell response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Clinical responses in a phase II study using adoptive transfer of short-term cultured tumor infiltration lymphocytes in metastatic melanoma patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
gp100 peptide vaccine and interleukin-2 in patients with advanced melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Somatic activation of KIT in distinct subtypes of melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sunitinib therapy for melanoma patients with KIT mutations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phase II, open-label, single-arm trial of imatinib mesylate in patients with metastatic melanoma harboring c-Kit mutation or amplification
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Frequency and spectrum of BRAF mutations in a retrospective, single-institution study of 1112 cases of melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Results of a phase III, randomized, placebo-controlled study of sorafenib in combination with carboplatin and paclitaxel as second-line treatment in patients with unresectable stage III or stage IV melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dabrafenib in BRAF-mutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dabrafenib in patients with Val600Glu or Val600Lys BRAF-mutant melanoma metastatic to the brain (BREAK-MB): a multicentre, open-label, phase 2 trial
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intratumoral molecular heterogeneity in a BRAF-mutant, BRAF inhibitor-resistant melanoma: a case illustrating the challenges for personalized medicine.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Acquired resistance to BRAF inhibitors mediated by a RAF kinase switch in melanoma can be overcome by cotargeting MEK and IGF-1R/PI3K
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Melanoma whole-exome sequencing identifies (V600E)B-RAF amplification-mediated acquired B-RAF inhibitor resistance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RAS mutations in cutaneous squamous-cell carcinomas in patients treated with BRAF inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RAF inhibition and induction of cutaneous squamous cell carcinoma.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Skin tumors induced by sorafenib; paradoxic RAS-RAF pathway activation and oncogenic mutations of HRAS, TP53, and TGFBR1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Atypical melanocytic proliferations and new primary melanomas in patients with advanced melanoma undergoing selective BRAF inhibition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Vemurafenib in melanoma with BRAF V600E mutation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Potential therapeutic strategies to overcome acquired resistance to BRAF or MEK inhibitors in BRAF mutant cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modelling vemurafenib resistance in melanoma reveals a strategy to forestall drug resistance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Improved survival with MEK inhibition in BRAF-mutated melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cutaneous side-effects of kinase inhibitors and blocking antibodies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2960802-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0140-6736(13)60802-8
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PubMed publication ID
24054424
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