(Q56902483)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9818186%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

review article

1 reference

title

Mechanistically diverse enzyme superfamilies: the importance of chemistry in the evolution of catalysis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9818186%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

2

P C Babbitt

1 reference

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6 December 2019

author name string

J A Gerlt

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9818186%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

language of work or name

English

0 references

publication date

1 October 1998

1 reference

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Current Opinion in Chemical Biology

6 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9818186%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

volume

2

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6 December 2019

page(s)

607-612

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9818186%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

issue

5

1 reference

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How big is the universe of exons?

6 December 2019

cites work

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7 January 2021

One thousand families for the molecular biologist

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7 January 2021

Evolutionary divergence of substrate specificity within the chymotrypsin-like serine protease fold

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7 January 2021

Understanding enzyme superfamilies. Chemistry As the fundamental determinant in the evolution of new catalytic activities

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7 January 2021

The enolase superfamily: a general strategy for enzyme-catalyzed abstraction of the alpha-protons of carboxylic acids

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7 January 2021

Mandelate racemase and muconate lactonizing enzyme are mechanistically distinct and structurally homologous

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7 January 2021

Octahedral coordination at the high-affinity metal site in enolase: crystallographic analysis of the MgII--enzyme complex from yeast at 1.9 A resolution

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7 January 2021

A functionally diverse enzyme superfamily that abstracts the alpha protons of carboxylic acids

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7 January 2021

Evolution of enzymatic activities in the enolase superfamily: partitioning of reactive intermediates by (D)-glucarate dehydratase from Pseudomonas putida

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7 January 2021

Evolution of enzymatic activities in the enolase superfamily: crystal structure of (D)-glucarate dehydratase from Pseudomonas putida

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7 January 2021

The crystal structure of enoyl-CoA hydratase complexed with octanoyl-CoA reveals the structural adaptations required for binding of a long chain fatty acid-CoA molecule

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7 January 2021

Structure of 4-chlorobenzoyl coenzyme A dehalogenase determined to 1.8 A resolution: an enzyme catalyst generated via adaptive mutation

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7 January 2021

Enoyl-CoA Hydratase and Isomerase form a Superfamily with a Common Active-Site Glutamate Residue

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7 January 2021

Enoyl-coenzyme A hydratase-catalyzed exchange of the alpha-protons of coenzyme A thiol esters: a model for an enolized intermediate in the enzyme-catalyzed elimination?

1 reference

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7 January 2021

Identification of active site residues essential to 4-chlorobenzoyl-coenzyme A dehalogenase catalysis by chemical modification and site directed mutagenesis

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7 January 2021

Beta1,4-N-acetylgalactosaminyltransferase (GM2 synthase) is released from Golgi membranes as a neuraminidase-sensitive, disulfide-bonded dimer by a cathepsin D-like protease

1 reference

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7 January 2021

Metabolism of ferulic acid to vanillin. A bacterial gene of the enoyl-SCoA hydratase/isomerase superfamily encodes an enzyme for the hydration and cleavage of a hydroxycinnamic acid SCoA thioester.

1 reference

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7 January 2021

Molecular characterization of the cai operon necessary for carnitine metabolism in Escherichia coli

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7 January 2021

Crystal structure of the biphenyl-cleaving extradiol dioxygenase from a PCB-degrading pseudomonad

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7 January 2021

Three-dimensional structures of free form and two substrate complexes of an extradiol ring-cleavage type dioxygenase, the BphC enzyme from Pseudomonas sp. strain KKS102

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7 January 2021

Crystal structure of human glyoxalase I--evidence for gene duplication and 3D domain swapping

1 reference

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7 January 2021

Fosfomycin resistance protein (FosA) is a manganese metalloglutathione transferase related to glyoxalase I and the extradiol dioxygenases

1 reference

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7 January 2021

Isomerization of (R)- and (S)- glutathiolactaldehydes by glyoxalase I: the case for dichotomous stereochemical behavior in a single active site

1 reference

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7 January 2021

An evolutionary treasure: unification of a broad set of amidohydrolases related to urease

1 reference

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7 January 2021

AtzC is a new member of the amidohydrolase protein superfamily and is homologous to other atrazine-metabolizing enzymes.

1 reference

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7 January 2021

The crystal structure of urease from Klebsiella aerogenes

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7 January 2021

Three-dimensional structure of the binuclear metal center of phosphotriesterase

1 reference

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7 January 2021

A pre-transition-state mimic of an enzyme: X-ray structure of adenosine deaminase with bound 1-deazaadenosine and zinc-activated water

1 reference

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7 January 2021

Biochemical characterization and crystallographic structure of an Escherichia coli protein from the phosphotriesterase gene family

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7 January 2021

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7 January 2021

The B12-dependent ribonucleotide reductase from the archaebacterium Thermoplasma acidophila: an evolutionary solution to the ribonucleotide reductase conundrum

1 reference

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7 January 2021

Epimerization via carbon-carbon bond cleavage. L-ribulose-5-phosphate 4-epimerase as a masked class II aldolase

1 reference

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7 January 2021

Metal-catalyzed oxidation and mutagenesis studies on the iron(II) binding site of 1-aminocyclopropane-1-carboxylate oxidase

1 reference

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7 January 2021

Identification of non-heme diiron proteins that catalyze triple bond and epoxy group formation

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7 January 2021

Insights into the mechanism of catalysis by the P-C bond-cleaving enzyme phosphonoacetaldehyde hydrolase derived from gene sequence analysis and mutagenesis.

1 reference

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7 January 2021

Computer analysis of bacterial haloacid dehalogenases defines a large superfamily of hydrolases with diverse specificity. Application of an iterative approach to database search

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7 January 2021

On the Evolution of Biochemical Syntheses

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7 January 2021

10.1016/S1367-5931(98)80091-4

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9818186%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

1 reference