(Q56933230)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21067438%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

Bifunctional phenolic-choline conjugates as anti-oxidants and acetylcholinesterase inhibitors (English)

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16 January 2020

1

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16 January 2020

Sérgio Marques

2

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16 January 2020

Pedro L. Falé

3

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16 January 2020

Sandra M. Cardoso

6

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16 January 2020

Catarina R. Oliveira

7

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16 January 2020

Maria L. Serralheiro

8

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16 January 2020

5

Daniela M Arduíno

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16 January 2020

author name string

Susana Santos

4

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16 January 2020

M Amélia Santos

9

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16 January 2020

publication date

11 November 2010

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Journal of Enzyme Inhibition and Medicinal Chemistry

16 January 2020

published in

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16 January 2020

volume

26

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16 January 2020

page(s)

485-497

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16 January 2020

issue

4

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Oxidative stress, antioxidants and neurodegenerative diseases

16 January 2020

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Treatment of Alzheimer's disease with a cholinesterase inhibitor combined with antioxidants

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Pathways towards and away from Alzheimer's disease

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Oxidative stress and neurotoxicity

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The crucial role of metal ions in neurodegeneration: the basis for a promising therapeutic strategy

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Pharmacotherapeutic targets in Alzheimer's disease

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Rational approach to discover multipotent anti-Alzheimer drugs.

21 January 2018

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Multi-target-directed drug design strategy: from a dual binding site acetylcholinesterase inhibitor to a trifunctional compound against Alzheimer's disease.

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Alzheimer's disease: new approaches to drug discovery

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Site-activated multifunctional chelator with acetylcholinesterase and neuroprotective-neurorestorative moieties for Alzheimer's therapy

21 January 2018

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New hydroxypyridinone iron-chelators as potential anti-neurodegenerative drugs

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Chroman/catechol hybrids: synthesis and evaluation of their activity against oxidative stress induced cellular damage.

21 January 2018

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Rosmarinic acid inhibits lung injury induced by diesel exhaust particles.

21 January 2018

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Protection of mouse brain from aluminum-induced damage by caffeic acid

21 January 2018

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A comparative study in rats of the in vitro and in vivo pharmacology of the acetylcholinesterase inhibitors tacrine, donepezil and NXX-066.

21 January 2018

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alpha,beta-Dehydrophenylalanine choline esters, a new class of reversible inhibitors of human acetylcholinesterase and butyrylcholinesterase

21 January 2018

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Screening for acetylcholinesterase inhibitory activity in plants used in Thai traditional rejuvenating and neurotonic remedies

21 January 2018

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Mechanism studies on the csi reaction with allyl ethers by varyingp-substituent

21 January 2018

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Structure-antifungal activity relationship of cinnamic acid derivatives.

21 January 2018

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21 January 2018

The Protein Data Bank

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Development and validation of a genetic algorithm for flexible docking

21 January 2018

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Strategies to assess blood-brain barrier penetration

21 January 2018

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Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

21 January 2018

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Acetylcholinesterase inhibitory activity of some Amaryllidaceae alkaloids and Narcissus extracts.

21 January 2018

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Design, synthesis, and biological evaluation of conformationally restricted rivastigmine analogues

21 January 2018

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Structural insights into substrate traffic and inhibition in acetylcholinesterase

21 January 2018

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Structure of acetylcholinesterase complexed with E2020 (Aricept): implications for the design of new anti-Alzheimer drugs

21 January 2018

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Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase

21 January 2018

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Free radicals, metals and antioxidants in oxidative stress-induced cancer

21 January 2018

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Amyloid processing and signal transduction properties of antiparkinson-antialzheimer neuroprotective drugs rasagiline and TV3326.

21 January 2018

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Neurodegenerative pathways in Parkinson's disease: therapeutic strategies

21 January 2018

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Alzheimer's disease-associated neurotoxic mechanisms and neuroprotective strategies.

21 January 2018

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Mitochondrial function in Parkinson's disease cybrids containing an nt2 neuron-like nuclear background.

21 January 2018

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21 January 2018

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Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death

21 January 2018

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Arisugacins, selective acetylcholinesterase inhibitors of microbial origin

21 January 2018

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10.3109/14756366.2010.529806

21 January 2018

Identifiers

DOI

1 reference

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16 January 2020

1 reference