(Q56985645)

English

Prediction of a Ligand-Binding Niche within a Human Olfactory Receptor by Combining Site-Directed Mutagenesis with Dynamic Homology Modeling

article

In more languages

Statements

scholarly article

0 references

Prediction of a Ligand-Binding Niche within a Human Olfactory Receptor by Combining Site-Directed Mutagenesis with Dynamic Homology Modeling (English)

0 references

1 reference

based on heuristic

inferred from title

object named as

Steffen Wolf

2

0 references

5

object named as

Klaus Gerwert

0 references

3

object named as

Hanns Hatt

0 references

1

object named as

Lian Gelis

0 references

author name string

Eva M. Neuhaus

4

0 references

language of work or name

0 references

publication date

5 December 2011

0 references

Angewandte Chemie International Edition

0 references

51

0 references

5

0 references

1274-1278

0 references

Molecular tinkering of G protein-coupled receptors: an evolutionary success

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

Functional expression of olfactory-adrenergic receptor chimeras and intracellular retention of heterologously expressed olfactory receptors

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

Deorphanizing vertebrate olfactory receptors: recent advances in odorant-response assays

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

Combinatorial receptor codes for odors

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

A novel multigene family may encode odorant receptors: a molecular basis for odor recognition

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

Computer-based de novo design of drug-like molecules

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

Processing and classification of chemical data inspired by insect olfaction

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

Predicting olfactory receptor neuron responses from odorant structure

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

Relationships between molecular structure and perceived odor quality of ligands for a human olfactory receptor

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

Subunit contributions to insect olfactory receptor function: channel block and odorant recognition

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

Analysis of the molecular basis for octanal interactions in the expressed rat 17 olfactory receptor

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

Molecular mechanisms underlying differential odor responses of a mouse olfactory receptor

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

Prediction of structure and function of G protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

Making sense of olfaction through predictions of the 3-D structure and function of olfactory receptors

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

Predicted 3-D structures for mouse I7 and rat I7 olfactory receptors and comparison of predicted odor recognition profiles with experiment

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

The molecular basis for ligand specificity in a mouse olfactory receptor: a network of functionally important residues.

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

Ligand specificity of odorant receptors.

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

Structural basis for a broad but selective ligand spectrum of a mouse olfactory receptor: mapping the odorant-binding site.

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

High-potency olfactory receptor agonists discovered by virtual high-throughput screening: molecular probes for receptor structure and olfactory function

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

Crystal structure of rhodopsin: A G protein-coupled receptor

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

The retinal conformation and its environment in rhodopsin in light of a new 2.2 A crystal structure

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

Crystal structure of the human beta2 adrenergic G-protein-coupled receptor

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

Crystal structure of squid rhodopsin

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

Crystal structure of the ligand-free G-protein-coupled receptor opsin

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

Structure of a beta1-adrenergic G-protein-coupled receptor

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

The mouse eugenol odorant receptor: structural and functional plasticity of a broadly tuned odorant binding pocket

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

GPCR 3D homology models for ligand screening: lessons learned from blind predictions of adenosine A2a receptor complex

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

Discovery of novel chemotypes to a G-protein-coupled receptor through ligand-steered homology modeling and structure-based virtual screening.

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

RosettaLigand docking with full ligand and receptor flexibility.

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

Modeling GPCR active state conformations: the β(2)-adrenergic receptor.

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

Molecular dynamics simulation of the human adenosine A3 receptor: agonist induced conformational changes of Trp243.

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

Dopamine D1 receptor agonist and D2 receptor antagonist effects of the natural product (-)-stepholidine: molecular modeling and dynamics simulations

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

Simulations of a G protein-coupled receptor homology model predict dynamic features and a ligand binding site

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

A specific heat shock protein enhances the expression of mammalian olfactory receptor proteins

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

Identification of a testicular odorant receptor mediating human sperm chemotaxis

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

Activation of an olfactory receptor inhibits proliferation of prostate cancer cells

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

Prediction of the odorant binding site of olfactory receptor proteins by human-mouse comparisons

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

The variable and conserved interfaces of modeled olfactory receptor proteins

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

The importance of odorant conformation to the binding and activation of a representative olfactory receptor

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

Activation of Pheromone-Sensitive Neurons Is Mediated by Conformational Activation of Pheromone-Binding Protein

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103980

21 January 2018

Identifiers

10.1002/ANIE.201103980

0 references

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q56985645&oldid=1856452606"