(Q57042164)

English

Nuclear genetic control of mitochondrial DNA segregation

article published in 2003

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scholarly article

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Nuclear genetic control of mitochondrial DNA segregation (English)

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mitochondrial DNA

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J Concepción Loredo-Osti

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object named as

J C Loredo-Osti

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author name string

Brendan J Battersby

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Eric A Shoubridge

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language of work or name

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publication date

February 2003

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Nature Genetics

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33

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2

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183-6

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https://scigraph.springernature.com/pub.10.1038/ng1073

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Mitochondrial DNA mutations in human disease.

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Progressive increase of the mutated mitochondrial DNA fraction in Kearns-Sayre syndrome

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Marked replicative advantage of human mtDNA carrying a point mutation that causes the MELAS encephalomyopathy

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Mitochondrial myopathy with progressive decrease in mitochondrial tRNA(Leu)(UUR) mutant genomes

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Different cellular backgrounds confer a marked advantage to either mutant or wild-type mitochondrial genomes.

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A novel heteroplasmic tRNAleu(CUN) mtDNA point mutation in a sporadic patient with mitochondrial encephalomyopathy segregates rapidly in skeletal muscle and suggests an approach to therapy.

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Maintenance of human rearranged mitochondrial DNAs in long-term cultured transmitochondrial cell lines

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Decrease of 3243 A-->G mtDNA mutation from blood in MELAS syndrome: a longitudinal study

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Random genetic drift in the female germline explains the rapid segregation of mammalian mitochondrial DNA.

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Tissue-specific selection for different mtDNA genotypes in heteroplasmic mice

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Replication of animal mitochondrial DNA.

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The inheritance of genes in mitochondria and chloroplasts: laws, mechanisms, and models

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Mutation in mitochondrial tRNALeu(UUR) gene in a large pedigree with maternally transmitted type II diabetes mellitus and deafness

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Extremely high levels of mutant mtDNAs co-localize with cytochrome c oxidase-negative ragged-red fibers in patients harboring a point mutation at nt 3243

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The generation of transplasmic Drosophila simulans by cytoplasmic injection: effects of segregation and selection on the perpetuation of mitochondrial DNA heteroplasmy.

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Finding the molecular basis of quantitative traits: successes and pitfalls.

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Selection of a mtDNA sequence variant in hepatocytes of heteroplasmic mice is not due to differences in respiratory chain function or efficiency of replication

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Mgm101p is a novel component of the mitochondrial nucleoid that binds DNA and is required for the repair of oxidatively damaged mitochondrial DNA

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In organello formaldehyde crosslinking of proteins to mtDNA: identification of bifunctional proteins

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Characterization of immature B cells by a novel monoclonal antibody, by turnover and by mitogen reactivity.

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Overview of QTL mapping software and introduction to map manager QT.

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A note on the calculation of empirical P values from Monte Carlo procedures.

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Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results

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