(Q57048245)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30279286%20AND%20SRC:MED&resulttype=core&format=json

26 April 2020

title

Proteome Analysis Reveals the Conidial Surface Protein CcpA Essential for Virulence of the Pathogenic Fungus Aspergillus fumigatus (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30279286%20AND%20SRC:MED&resulttype=core&format=json

Conidial cell wall protein A

26 April 2020

main subject

1 reference

GeneDB

short chain dehydrogenase atsC, putative

5 February 2019

0 references

putative oxidoreductase, 2OG-Fe(II) oxygenase family protein

0 references

protein of unknown function

0 references

Ortholog of Aspergillus fumigatus A1163 : AFUB_003990

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Ortholog(s) have cell adhesion molecule binding, glucan endo-1,6-beta-glucosidase activity, glucan exo-1,3-beta-glucosidase activity

0 references

FG-GAP repeat protein

0 references

Ortholog(s) have ARF guanyl-nucleotide exchange factor activity, role in SRP-dependent cotranslational protein targeting to membrane and Ssh1 translocon complex localization

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Has domain(s) with predicted phosphoric diester hydrolase activity and role in lipid metabolic process

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40S ribosomal protein S3

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Secreted beta-glucosidase

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Ortholog(s) have glutathione disulfide oxidoreductase activity, glutathione peroxidase activity, glutathione transferase activity

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Putative translation elongation factor EF-1 alpha subunit

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Molecular chaperone

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Protein with Yap1-dependent induction in response to hydrogen peroxide

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putative phosphoglycerate kinase

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Putative eukaryotic translation elongation factor 1 subunit eEF1-beta

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Ortholog(s) have copper ion binding, superoxide dismutase activity and role in cellular response to superoxide, evasion or tolerance by symbiont of host-produced reactive oxygen species, pathogenesis, superoxide metabolic process

0 references

Ortholog(s) have glycine dehydrogenase (decarboxylating) activity, role in glycine catabolic process, one-carbon metabolic process, protein lipoylation and mitochondrion localization

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Protein of unknown function identified by mass spectrometry

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Has domain(s) with predicted DNA binding, protein heterodimerization activity, role in DNA-templated transcription, initiation, nucleosome assembly and nucleosome, nucleus localization

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Histone H3

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exo-beta-1,3-glucanase

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Putative manganese superoxide dismutase

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Putative alpha-glucosidase B

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Putative heat shock protein

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1,3-beta-glucanosyltransferase with a role in elongation of 1,3-beta-glucan chains

0 references

Ortholog of Neosartorya fischeri NRRL 181 : NFIA_034050, NFIA_063470, Aspergillus wentii : Aspwe1_0038124, Aspwe1_0546044 and Aspergillus versicolor : Aspve1_0029373

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14-3-3 family protein

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Putative pheromone processing carboxypeptidase

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Ortholog of Aspergillus fumigatus A1163 : AFUB_022080

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Ortholog(s) have extracellular region localization

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Ortholog of Neosartorya fischeri NRRL 181 : NFIA_082360 and Aspergillus fumigatus A1163 : AFUB_022660

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Ribosomal protein L18

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Has domain(s) with predicted heme binding activity

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Putative mitochondrial Hsp70 chaperone

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Immunoreactive protein

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Allergen Asp f 8

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Putative acylCoA binding family protein

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Ortholog(s) have role in cellular metal ion homeostasis, cellular response to biotic stimulus and cellular response to starvation, more

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Ortholog(s) have role in intracellular sterol transport and fungal-type vacuole lumen localization

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Putative ATP synthase oligomycin sensitivity conferral protein

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Allergen Asp f 13

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Putative translation elongation factor EF-2 subunit

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Transcript up-regulated in conidia exposed to neutrophils

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Ortholog of Aspergillus fumigatus A1163 : AFUB_029950

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Conidia-enriched protein of unknown function

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Cell wall glucanase

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Mycelial catalase

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Aspergillopepsin II

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Ortholog of A. oryzae RIB40 : AO090010000310, Aspergillus wentii : Aspwe1_0294100, Aspwe1_0531408, Aspergillus niger ATCC 1015 : 53802-mRNA and Aspergillus terreus NIH2624 : ATET_10090

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Histone H2B

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Ortholog(s) have ribosomal small subunit binding, translation initiation factor activity, translation initiation factor binding activity and role in formation of translation preinitiation complex, maintenance of translational fidelity

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Putative glutaminase A

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Putative peptidyl-prolyl cis-trans isomerase

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Putative inorganic diphosphatase

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Putative protease

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Ortholog of Neosartorya fischeri NRRL 181 : NFIA_067470 and Aspergillus fumigatus A1163 : AFUB_039340

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Ubiquitin

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Aspartic acid endopeptidase

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Ortholog of A. nidulans FGSC A4 : AN2894, A. niger CBS 513.88 : An02g07350, A. oryzae RIB40 : AO090003000710, Aspergillus wentii : Aspwe1_0025131 and Aspergillus sydowii : Aspsy1_0775782

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Non-histone chromosomal protein

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Putative glutathione peroxidase

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Has domain(s) with predicted NADH dehydrogenase (ubiquinone) activity and mitochondrion localization

0 references

Ortholog of A. niger CBS 513.88 : An09g04240, A. oryzae RIB40 : AO090012000670, Neosartorya fischeri NRRL 181 : NFIA_063040 and Aspergillus wentii : Aspwe1_0038047

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Dehydrin-like protein

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Asp hemolysin-like protein

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Putative cell wall galactomannoprotein

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Putative secreted protease

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Putative outer mitochondrial membrane protein porin

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Putative glycophosphatidylinositol (GPI)-anchored cell wall protein

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BYS1 domain protein

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Putative extracellular lipase

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cytochrome c oxidase subunit Va with a predicted role in oxidative phosphorylation

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Ortholog(s) have flavin-linked sulfhydryl oxidase activity, role in oxidation-reduction process and extracellular region localization

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Heat shock protein

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Putative single-stranded DNA binding protein family member

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Autophagic (vacuolar) serine protease

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Cu/Zn superoxide dismutase

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Conidial hydrophobin

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ATP synthase F1, beta subunit

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Cofilin

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Allergen Asp f 29

0 references

Ortholog of A. nidulans FGSC A4 : AN6856, A. niger CBS 513.88 : An14g06050, A. oryzae RIB40 : AO090120000435, Aspergillus wentii : Aspwe1_0107169 and Aspergillus sydowii : Aspsy1_0040420

0 references

Putative Hsp90 binding co-chaperone

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Glucose-repressible gene

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Allergen Asp f 3

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protein of unknown function

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Nascent polypeptide-associated complex subunit alpha

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actin

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Putative NAD-dependent malate dehydrogenase with a predicted role in the citric acid cycle

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Ortholog(s) have RNA binding activity and role in mRNA splicing, via spliceosome, maturation of SSU-rRNA

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Putative enolase

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Ortholog of A. nidulans FGSC A4 : AN1941, A. niger CBS 513.88 : An11g02730, Neosartorya fischeri NRRL 181 : NFIA_053540 and Aspergillus versicolor : Aspve1_0025340

0 references

Allergen Asp f 28

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Ortholog(s) have chaperone binding, unfolded protein binding activity, role in chaperone-mediated protein complex assembly, protein import into mitochondrial intermembrane space, protein refolding and mitochondrial matrix localization

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protein of unknown function

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flavoprotein amide oxidase (FAD)

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Putative FK506-binding protein (FKBP)-type peptidyl-prolyl cis-trans isomerase

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Putative heat shock protein

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Ortholog(s) have hydrolase activity, role in nucleotide metabolic process and cytosol, nucleus localization

0 references

Ortholog of A. nidulans FGSC A4 : AN5353, A. niger CBS 513.88 : An02g05680, A. oryzae RIB40 : AO090103000108, Aspergillus wentii : Aspwe1_0131073 and Aspergillus sydowii : Aspsy1_0050268

0 references

Ortholog of A. nidulans FGSC A4 : AN7941, A. fumigatus Af293 : Afu2g12680, A. niger CBS 513.88 : An03g01770, Aspergillus sydowii : Aspsy1_0156290 and Aspergillus terreus NIH2624 : ATET_07370

0 references

Has domain(s) with predicted hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances activity, role in proton transport and vacuolar proton-transporting V-type ATPase complex localization

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Ortholog of A. nidulans FGSC A4 : AN4256, A. oryzae RIB40 : AO090012000139, Neosartorya fischeri NRRL 181 : NFIA_099750 and Aspergillus versicolor : Aspve1_0055292

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Putative tropomyosin 1

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Putative NAD-dependent malate dehydrogenase

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Putative secreted 1,4-beta-D-glucan glucanhydrolase

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Has domain(s) with predicted role in cell adhesion

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Ortholog(s) have extracellular region localization

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Putative secreted N-acetylhexosaminidase

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Putative mitochondrial F1 ATPase subunit alpha

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Putative glycosylphosphatidylinositol (GPI)-linked protein

0 references

Has domain(s) with predicted role in protein folding and cytoplasm localization

0 references

Ortholog of A. nidulans FGSC A4 : AN1603, Neosartorya fischeri NRRL 181 : NFIA_098760, NFIA_099140, Aspergillus wentii : Aspwe1_0689083 and Aspergillus versicolor : Aspve1_0037404

0 references

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2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30279286%20AND%20SRC:MED&resulttype=core&format=json

26 April 2020

Alexander Scheffold

14

1 reference

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26 April 2020

Juergen Loeffler

15

1 reference

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26 April 2020

Olaf Kniemeyer

20

1 reference

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26 April 2020

Axel A Brakhage

23

1 reference

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26 April 2020

21

Scott G Filler

1 reference

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26 April 2020

5

Thorsten Heinekamp

1 reference

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26 April 2020

author name string

Vera Voltersen

1

1 reference

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26 April 2020

Sahra Herrmann

3

1 reference

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26 April 2020

Franziska Schmidt

4

1 reference

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26 April 2020

Maria Strassburger

6

1 reference

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26 April 2020

Thomas Krüger

7

1 reference

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26 April 2020

Petra Bacher

8

1 reference

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26 April 2020

Jasmin Lother

9

1 reference

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26 April 2020

Esther Weiss

10

1 reference

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26 April 2020

Kerstin Hünniger

11

1 reference

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26 April 2020

Hong Liu

12

1 reference

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26 April 2020

Peter Hortschansky

13

1 reference

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26 April 2020

Sven Krappmann

16

1 reference

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26 April 2020

Sandor Nietzsche

17

1 reference

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26 April 2020

Oliver Kurzai

18

1 reference

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26 April 2020

Utz Reichard

22

1 reference

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26 April 2020

Hermann Einsele

19

1 reference

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26 April 2020

language of work or name

English

0 references

publication date

2 October 2018

1 reference

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26 April 2020

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26 April 2020

volume

9

1 reference

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26 April 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30279286%20AND%20SRC:MED&resulttype=core&format=json

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

26 April 2020

cites work

1 reference

12 December 2020

Interleukin-8, a chemotactic and inflammatory cytokine

1 reference

12 December 2020

Purification and characterisation of an extracellular serine proteinase from Aspergillus fumigatus and its detection in tissue

1 reference

12 December 2020

Flow cytometric studies of oxidative product formation by neutrophils: a graded response to membrane stimulation.

1 reference

12 December 2020

Fitting a mixture model by expectation maximization to discover motifs in biopolymers

1 reference

12 December 2020

Use of reporter genes to identify recessive trans-acting mutations specifically involved in the regulation of Aspergillus nidulans penicillin biosynthesis genes

1 reference

12 December 2020

rodletless mutants of Aspergillus fumigatus

1 reference

12 December 2020

Molecular typing of environmental and patient isolates of Aspergillus fumigatus from various hospital settings.

1 reference

12 December 2020

Concentrations of airborne Aspergillus compared to the incidence of invasive aspergillosis: lack of correlation

1 reference

12 December 2020

A hidden Markov model for predicting transmembrane helices in protein sequences

1 reference

12 December 2020

Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes

1 reference

12 December 2020

The pathobiology of Aspergillus fumigatus

1 reference

12 December 2020

Infections caused by filamentous fungi in patients with hematologic malignancies. A report of 391 cases by GIMEMA Infection Program.

1 reference

12 December 2020

Menacing mold: the molecular biology of Aspergillus fumigatus

1 reference

12 December 2020

Deletion of the Aspergillus fumigatus lysine biosynthesis gene lysF encoding homoaconitase leads to attenuated virulence in a low-dose mouse infection model of invasive aspergillosis

1 reference

12 December 2020

Differences in patterns of infection and inflammation for corticosteroid treatment and chemotherapy in experimental invasive pulmonary aspergillosis

1 reference

12 December 2020

Protein production by auto-induction in high density shaking cultures

1 reference

12 December 2020

Deletion and allelic exchange of the Aspergillus fumigatus veA locus via a novel recyclable marker module.

1 reference

12 December 2020

Methylcitrate synthase from Aspergillus fumigatus. Propionyl-CoA affects polyketide synthesis, growth and morphology of conidia.

1 reference

12 December 2020

Gene targeting in Aspergillus fumigatus by homologous recombination is facilitated in a nonhomologous end- joining-deficient genetic background

1 reference

12 December 2020

Cyclophosphamide augments inflammation by reducing immunosuppression in a mouse model of allergic airway disease

1 reference

12 December 2020

Neutropenia induced in outbred mice by a simplified low-dose cyclophosphamide regimen: characterization and applicability to diverse experimental models of infectious diseases

1 reference

12 December 2020

Proteome of conidial surface associated proteins of Aspergillus fumigatus reflecting potential vaccine candidates and allergens

1 reference

12 December 2020

Analysis of the regulation, expression, and localisation of the isocitrate lyase from Aspergillus fumigatus, a potential target for antifungal drug development.

1 reference

12 December 2020

Phagocytosis of Aspergillus fumigatus conidia by murine macrophages involves recognition by the dectin-1 beta-glucan receptor and Toll-like receptor 2

1 reference

12 December 2020

Deletion of the gliP gene of Aspergillus fumigatus results in loss of gliotoxin production but has no effect on virulence of the fungus in a low-dose mouse infection model

1 reference

12 December 2020

Invasive fungal infections in allogeneic and autologous stem cell transplant recipients: a single-center study of 166 transplanted patients.

1 reference

12 December 2020

Fungal infections in hematopoietic stem cell transplant recipients

1 reference

12 December 2020

Impact of mycophenolic acid on the functionality of human polymorphonuclear neutrophils and dendritic cells during interaction with Aspergillus fumigatus

1 reference

12 December 2020

Invasive aspergillosis in chronic granulomatous disease

1 reference

12 December 2020

LC-MS/MS-based proteome profiling in Daphnia pulex and Daphnia longicephala: the Daphnia pulex genome database as a key for high throughput proteomics in Daphnia

1 reference

12 December 2020

Immune Sensing of Aspergillus fumigatus Proteins, Glycolipids, and Polysaccharides and the Impact on Th Immunity and Vaccination

1 reference

12 December 2020

Surface hydrophobin prevents immune recognition of airborne fungal spores

1 reference

12 December 2020

The Aspergillus Genome Database, a curated comparative genomics resource for gene, protein and sequence information for the Aspergillus research community

1 reference

12 December 2020

Using a new GPI-anchored-protein identification system to mine the protein databases of Aspergillus fumigatus, Aspergillus nidulans, and Aspergillus oryzae

1 reference

12 December 2020

Scaffold: a bioinformatic tool for validating MS/MS-based proteomic studies

1 reference

12 December 2020

In vivo bioluminescence imaging and histopathopathologic analysis reveal distinct roles for resident and recruited immune effector cells in defense against invasive aspergillosis

1 reference

12 December 2020

Interaction of phagocytes with filamentous fungi

1 reference

12 December 2020

Role of Aspergillus fumigatus DvrA in host cell interactions and virulence

1 reference

12 December 2020

Aspergillus fumigatus: contours of an opportunistic human pathogen

1 reference

12 December 2020

Secreted glutamic protease rescues aspartic protease Pep deficiency in Aspergillus fumigatus during growth in acidic protein medium

1 reference

12 December 2020

Conidial Dihydroxynaphthalene Melanin of the Human Pathogenic Fungus Aspergillus fumigatus Interferes with the Host Endocytosis Pathway

1 reference

12 December 2020

The role of Dectin-1 in the host defence against fungal infections

1 reference

12 December 2020

Concentration of antifungal agents within host cell membranes: a new paradigm governing the efficacy of prophylaxis

1 reference

12 December 2020

SignalP 4.0: discriminating signal peptides from transmembrane regions

1 reference

12 December 2020

The Arthroderma benhamiae hydrophobin HypA mediates hydrophobicity and influences recognition by human immune effector cells

1 reference

12 December 2020

Development stage-specific proteomic profiling uncovers small, lineage specific proteins most abundant in the Aspergillus Fumigatus conidial proteome

1 reference

12 December 2020

Regulatory T-cell modulation using cyclophosphamide in vaccine approaches: a current perspective

1 reference

12 December 2020

Hidden killers: human fungal infections

1 reference

12 December 2020

Aspergillus fumigatus melanins: interference with the host endocytosis pathway and impact on virulence.

1 reference

12 December 2020

Antigen-reactive T cell enrichment for direct, high-resolution analysis of the human naive and memory Th cell repertoire

1 reference

12 December 2020

The RodA hydrophobin on Aspergillus fumigatus spores masks dectin-1- and dectin-2-dependent responses and enhances fungal survival in vivo.

1 reference

12 December 2020

The Aspergillus Genome Database: multispecies curation and incorporation of RNA-Seq data to improve structural gene annotations

1 reference

12 December 2020

Surface structure characterization of Aspergillus fumigatus conidia mutated in the melanin synthesis pathway and their human cellular immune response

1 reference

12 December 2020

Aspergillus cell wall and biofilm

1 reference

12 December 2020

Identification of immunogenic antigens from Aspergillus fumigatus by direct multiparameter characterization of specific conventional and regulatory CD4+ T cells.

1 reference

12 December 2020

The pH-responsive PacC transcription factor of Aspergillus fumigatus governs epithelial entry and tissue invasion during pulmonary aspergillosis

1 reference

12 December 2020

Interference of Aspergillus fumigatus with the immune response

1 reference

12 December 2020

Divergent targets of Aspergillus fumigatus AcuK and AcuM transcription factors during growth in vitro versus invasive disease

1 reference

12 December 2020

A second stimulus required for enhanced antifungal activity of human neutrophils in blood is provided by anaphylatoxin C5a.

1 reference

12 December 2020

Aspergillus fumigatus CalA binds to integrin α5β1 and mediates host cell invasion

1 reference

12 December 2020

An LaeA- and BrlA-Dependent Cellular Network Governs Tissue-Specific Secondary Metabolism in the Human Pathogen Aspergillus fumigatus.

1 reference

12 December 2020

Identifiers

DOI

10.1128/MBIO.01557-18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30279286%20AND%20SRC:MED&resulttype=core&format=json

26 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30279286%20AND%20SRC:MED&resulttype=core&format=json

26 April 2020

1 reference