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Photopharmacology: Beyond Proof of Principle

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Photopharmacology: Beyond Proof of Principle (English)

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Wiktor Szymanski

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Ben Feringa

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Ben L. Feringa

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Willem A Velema

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Willem A. Velema

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English

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publication date

4 February 2014

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14

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Journal of the American Chemical Society

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volume

136

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issue

6

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page(s)

2178-2191

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Photodynamic therapy in dermatology

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How many drug targets are there?

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Redox potential of azobenzene as an amino acid residue in peptides

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Azobenzene photoswitches for biomolecules

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Molecular mechanisms of nociception

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Analysis of steroid hormones in a typical dairy waste disposal system

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CLINICAL APPLICATIONS OF COOMASSIE BLUE.

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Reversible photocontrol of biological systems by the incorporation of molecular photoswitches

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p-(4-Azipentyl)propofol: a potent photoreactive general anesthetic derivative of propofol

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The influence of drug polarity on the absorption of opioid drugs into CSF and subsequent cephalad migration following lumbar epidural administration: application to morphine and pethidine

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Recent advances in the photochemical control of protein function

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Classical Chemotherapy: Mechanisms, Toxicities and the Therapeutc Window

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Steroid hormone profiles of urban and tidal rivers using LC/MS/MS equipped with electrospray ionization and atmospheric pressure photoionization sources

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Adverse drug reactions: definitions, diagnosis, and management

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Azobenzene photoswitches for Staudinger-Bertozzi ligation

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Photomodulation of conformational states. Synthesis of cyclic peptides with backbone-azobenzene moieties

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Photodynamic therapy in oncology

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Photoremovable protecting groups in chemistry and biology: reaction mechanisms and efficacy.

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Spacer-based selectivity in the binding of "two-prong" ligands to recombinant human carbonic anhydrase I.

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Society's failure to protect a precious resource: antibiotics

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Synergistic drug combinations tend to improve therapeutically relevant selectivity

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Azobenzene photoswitching without ultraviolet light.

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Diarylethenes for Memories and Switches

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11 October 2022

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Low dose balsalazide (1.5 g twice daily) and mesalazine (0.5 g three times daily) maintained remission of ulcerative colitis but high dose balsalazide (3.0 g twice daily) was superior in preventing relapses

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1021/JA413063E

Photodynamic therapy in dermatology

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1021/JA413063E

Photoregulation of biological activity by photochromic reagents. 3. Photoregulation of bioelectricity by acetylcholine receptor inhibitors

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Robust visible light photoswitching with ortho-thiol substituted azobenzenes

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A Photochromic Agonist of AMPA Receptors

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Oncologic photodynamic therapy photosensitizers: a clinical review

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Perspectives on cancer therapy-induced mucosal injury: pathogenesis, measurement, epidemiology, and consequences for patients

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Development of first photoresponsive prodrug of paclitaxel.

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11 October 2022

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Investigation into the P3 binding domain of m-calpain using photoswitchable diazo- and triazene-dipeptide aldehydes: new anticataract agents

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Improved photocontrol of alpha-chymotrypsin activity: peptidomimetic trifluoromethylketone photoswitch enzyme inhibitors

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Optical control of antibacterial activity

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Antibiotics and antibiotic resistance genes in natural environments

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Exploring the pharmacology and action spectra of photochromic open-channel blockers

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Anticancer drugs and cardiotoxicity: Insights and perspectives in the era of targeted therapy

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Pathobiology of chemotherapy-induced hair loss

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Role of activated oxygen species in photodynamic therapy

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Abc amino acids: design, synthesis, and properties of new photoelastic amino acids.

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Rhodopsin-like protein from the purple membrane of Halobacterium halobium

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European Surveillance of Antimicrobial Consumption (ESAC): systemic antiviral use in Europe

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Photochemical control of biological processes

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Photoswitching azo compounds in vivo with red light.

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Optical control of TRPV1 channels

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Quantitative structure-pharmacokinetic/pharmacodynamic relationships

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Tuning photochromic ion channel blockers

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Augmented photoswitching modulates immune signaling

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Principles and applications of the photochemical control of cellular processes.

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Synthesis and structure-activity relations of disodium cromoglycate and some related compounds

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Rapid optical control of nociception with an ion-channel photoswitch

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Design, synthesis, and inhibitory activity of potent, photoswitchable mast cell activation inhibitors

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Photoisomerization in different classes of azobenzene

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Pharmacogenetics and adverse drug reactions

1 reference

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Redox characteristics of the eukaryotic cytosol

1 reference

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A photoswitchable ITAM peptidomimetic: synthesis and real time surface plasmon resonance (SPR) analysis of the effects of cis-trans isomerization on binding.

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Photomodulation of conformational states. IV. Integrin-binding RGD-peptides with (4-aminomethyl)phenylazobenzoic acid as backbone constituent.

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Method of the Year 2010

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11 October 2022

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Regulation of human carbonic anhydrase I (hCAI) activity by using a photochromic inhibitor

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Antimicrobial pharmacodynamics: critical interactions of 'bug and drug'.

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Successful treatment of recalcitrant chronic idiopathic urticaria with sulfasalazine

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A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma

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Photochromic blockers of voltage-gated potassium channels

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11 October 2022

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Biologically active molecules with a "light switch".

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11 October 2022

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Switching between low and high affinity for the Syk tandem SH2 domain by irradiation of azobenzene containing ITAM peptidomimetics.

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The tandem Src homology 2 domain of the Syk kinase: a molecular device that adapts to interphosphotyrosine distances

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Light control of mitochondrial complex I activity by a photoresponsive inhibitor

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The cancer biomarker problem

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Photoswitching of ortho-substituted azonium ions by red light in whole blood

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1021/JA413063E

Azobenzene as conformational switch in model peptides.

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https://opencitations.net/index/coci/api/v1/references/10.1021/JA413063E

Identifiers

DOI

10.1021/JA413063E

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PubMed publication ID

24456115

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(Q57075245)

Photopharmacology: Beyond Proof of Principle

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