(Q57086097)

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Prostaglandin PGE2 at very low concentrations suppresses collagen cleavage in cultured human osteoarthritic articular cartilage: this involves a decrease in expression of proinflammatory genes, collagenases and COL10A1, a gene linked to chondrocyte h

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Prostaglandin PGE2 at very low concentrations suppresses collagen cleavage in cultured human osteoarthritic articular cartilage: this involves a decrease in expression of proinflammatory genes, collagenases and COL10A1, a gene linked to chondrocyte h (English)

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object named as

Elena V Tchetina

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author name string

John A Di Battista

2

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David J Zukor

3

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John Antoniou

4

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A Robin Poole

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language of work or name

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2007

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Arthritis Research and Therapy

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9

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4

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R75

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https://scigraph.springernature.com/pub.10.1186/ar2273

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Contribution of runt-related transcription factor 2 to the pathogenesis of osteoarthritis in mice after induction of knee joint instability.

1 reference

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2 November 2018

Prostaglandin E2 stimulates p53 transactivational activity through specific serine 15 phosphorylation in human synovial fibroblasts. Role in suppression of c/EBP/NF-kappaB-mediated MEKK1-induced MMP-1 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2206385

2 November 2018

Transforming growth factor-beta2 suppresses collagen cleavage in cultured human osteoarthritic cartilage, reduces expression of genes associated with chondrocyte hypertrophy and degradation, and increases prostaglandin E(2) production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2206385

2 November 2018

Differential direct effects of cyclo-oxygenase-1/2 inhibition on proteoglycan turnover of human osteoarthritic cartilage: an in vitro study

1 reference

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Is COX-2 a perpetrator or a protector? Selective COX-2 inhibitors remain controversial.

1 reference

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2 November 2018

Increased type II collagen degradation and very early focal cartilage degeneration is associated with upregulation of chondrocyte differentiation related genes in early human articular cartilage lesions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2206385

2 November 2018

Prostaglandin signaling in the renal collecting duct: release, reuptake, and oxidation in the same cell

1 reference

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Immunolocalization of low-affinity prostaglandin E receptors, EP and EP, in adult human epidermis

1 reference

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2 November 2018

PGE2 signal through EP2 promotes the growth of articular chondrocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2206385

2 November 2018

Role of interleukin-1 and tumor necrosis factor alpha in matrix degradation of human osteoarthritic cartilage.

1 reference

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2 November 2018

PGE2 inhibits chondrocyte differentiation through PKA and PKC signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2206385

2 November 2018

Primary murine limb bud mesenchymal cells in long-term culture complete chondrocyte differentiation: TGF-beta delays hypertrophy and PGE2 inhibits terminal differentiation.

1 reference

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2 November 2018

Cyclooxygenase-2 and prostaglandins in articular tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2206385

2 November 2018

Simultaneous stimulation of EP2 and EP4 is essential to the effect of prostaglandin E2 in chondrocyte differentiation

1 reference

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2 November 2018

The role of prostaglandin E2 receptors in the pathogenesis of rheumatoid arthritis

1 reference

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2 November 2018

Evaluation of the influence of prostaglandin E2 on recombinant equine interleukin-1beta-stimulated matrix metalloproteinases 1, 3, and 13 and tissue inhibitor of matrix metalloproteinase 1 expression in equine chondrocyte cultures

1 reference

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Nutraceutical fatty acids as biochemical and molecular modulators of skeletal biology

1 reference

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2 November 2018

The contributions of cyclooxygenase-2 to tumor angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2206385

2 November 2018

Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2206385

2 November 2018

Superinduction of cyclooxygenase-2 activity in human osteoarthritis-affected cartilage. Influence of nitric oxide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2206385

2 November 2018

Effects of prostaglandins on deoxyribonucleic acid and aggrecan synthesis in the RCJ 3.1C5.18 chondrocyte cell line: role of second messengers

1 reference

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2 November 2018

A cyclic adenosine 3',5'-monophosphate signal is required for the induction of IL-1 beta by TNF-alpha in human monocytes

1 reference

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2 November 2018

IL-1-induced nitric oxide inhibits chondrocyte proliferation via PGE2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2206385

2 November 2018

Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2206385

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Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue.

1 reference

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Modulation of glucocorticoid receptor expression in human articular chondrocytes by cAMP and prostaglandins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2206385

2 November 2018

Prostaglandin E1 inhibits collagenase gene expression in rabbit synoviocytes and human fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2206385

2 November 2018

Studies of the articular cartilage proteoglycan aggrecan in health and osteoarthritis. Evidence for molecular heterogeneity and extensive molecular changes in disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2206385

2 November 2018

The effect of tumor necrosis factor alpha and gamma-interferon on the resorption of human articular cartilage and on the production of prostaglandin E and of caseinase activity by human articular chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17683641

12 December 2020

based on heuristic

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Influence of prostaglandins on DNA and matrix synthesis in growth plate chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17683641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of apoptosis in bovine articular chondrocyte by prostaglandin E(2) through cAMP-dependent pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/17683641

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inferred from PubMed ID database lookup

Comparison of the degradation of type II collagen and proteoglycan in nasal and articular cartilages induced by interleukin-1 and the selective inhibition of type II collagen cleavage by collagenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17683641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective enhancement of collagenase-mediated cleavage of resident type II collagen in cultured osteoarthritic cartilage and arrest with a synthetic inhibitor that spares collagenase 1 (matrix metalloproteinase 1)

1 reference

https://pubmed.ncbi.nlm.nih.gov/17683641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of cyclooxygenase by interleukin 1: comparative study between human synovial cells and chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17683641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prostaglandins E2 and E1 inhibit cytokine-induced metalloprotease expression in human synovial fibroblasts. Mediation by cyclic-AMP signalling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/17683641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prostaglandin E2 stimulates incorporation of proline into collagenase digestible proteins in human articular chondrocytes: identification of an effector autocrine loop involving insulin-like growth factor I

1 reference

https://pubmed.ncbi.nlm.nih.gov/17683641

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inferred from PubMed ID database lookup

The effect of prostaglandin E2 on costochondral chondrocyte differentiation is mediated by cyclic adenosine 3',5'-monophosphate and protein kinase C

1 reference

https://pubmed.ncbi.nlm.nih.gov/17683641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inducible cyclooxygenase may have anti-inflammatory properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/17683641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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