(Q57148790)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22388934%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

title

BMPR-II deficiency elicits pro-proliferative and anti-apoptotic responses through the activation of TGFβ-TAK1-MAPK pathways in PAH (English)

1 reference

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24 January 2020

1 reference

7

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24 January 2020

author name string

Md Talat Nasim

1

1 reference

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24 January 2020

Takeshi Ogo

2

1 reference

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24 January 2020

Lan Zhao

4

1 reference

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24 January 2020

Chien-nien Chen

5

1 reference

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24 January 2020

Christopher Rhodes

6

1 reference

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24 January 2020

Hasnin M Chowdhury

3

1 reference

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24 January 2020

publication date

2 March 2012

1 reference

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24 January 2020

published in

Human Molecular Genetics

1 reference

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24 January 2020

volume

21

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24 January 2020

issue

11

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24 January 2020

page(s)

2548-2558

1 reference

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Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension

24 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS073

Bone morphogenetic protein signalling in heritable versus idiopathic pulmonary hypertension

21 January 2018

1 reference

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Inhibition of rat vascular smooth muscle proliferation in vitro and in vivo by bone morphogenetic protein-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS073

Dysfunctional Smad Signaling Contributes to Abnormal Smooth Muscle Cell Proliferation in Familial Pulmonary Arterial Hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS073

Altered growth responses of pulmonary artery smooth muscle cells from patients with primary pulmonary hypertension to transforming growth factor-beta(1) and bone morphogenetic proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS073

Activin-like kinase 5 (ALK5) mediates abnormal proliferation of vascular smooth muscle cells from patients with familial pulmonary arterial hypertension and is involved in the progression of experimental pulmonary arterial hypertension induced by mo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS073

Altered bone morphogenetic protein and transforming growth factor-beta signaling in rat models of pulmonary hypertension: potential for activin receptor-like kinase-5 inhibition in prevention and progression of disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS073

The extracellular signal-regulated kinase is involved in the effects of sildenafil on pulmonary vascular remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS073

Serotonin increases susceptibility to pulmonary hypertension in BMPR2-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS073

Mice expressing BMPR2R899X transgene in smooth muscle develop pulmonary vascular lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS073

Inhibition of p38 MAPK reverses hypoxia-induced pulmonary artery endothelial dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS073

Transforming growth factor-beta (TGF-beta) and TGF-beta-associated kinase 1 are required for R-Ras-mediated transformation of mammary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS073

Activation of the bone morphogenetic protein receptor by H11kinase/Hsp22 promotes cardiac cell growth and survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS073

Smad6 is a Smad1/5-induced smad inhibitor. Characterization of bone morphogenetic protein-responsive element in the mouse Smad6 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS073

A direct interaction between TGFbeta activated kinase 1 and the TGFbeta type II receptor: implications for TGFbeta signalling and cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS073

Stoichiometric imbalance in the receptor complex contributes to dysfunctional BMPR-II mediated signalling in pulmonary arterial hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS073

TAK1 is an essential regulator of BMP signalling in cartilage

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS073

Transforming growth factor-beta-activated kinase-1 (TAK1), a MAP3K, interacts with Smad proteins and interferes with osteogenesis in murine mesenchymal progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS073

Transforming growth factor-beta1 (TGF-beta)-induced apoptosis of prostate cancer cells involves Smad7-dependent activation of p38 by TGF-beta-activated kinase 1 and mitogen-activated protein kinase kinase 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS073

Elevated Levels of Inflammatory Cytokines Predict Survival in Idiopathic and Familial Pulmonary Arterial Hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS073

Interleukin-6 overexpression induces pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS073

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS073

Pivotal role of cardiomyocyte TGF-β signaling in the murine pathological response to sustained pressure overload

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS073

HnRNP G and Tra2beta: opposite effects on splicing matched by antagonism in RNA binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS073

A double-reporter splicing assay for determining splicing efficiency in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS073

A dual-light reporter system to determine the efficiency of protein-protein interactions in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS073

21 January 2018

Identifiers

DOI

10.1093/HMG/DDS073

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22388934%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

1 reference