(Q57177662)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29758235%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

title

Innovation and trends in the development and approval of antiviral medicines: 1987-2017 and beyond (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29758235%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29758235%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

author name string

Julian A Symons

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29758235%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Jerome Deval

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29758235%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

language of work or name

English

0 references

publication date

15 May 2018

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29758235%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29758235%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

volume

155

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29758235%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

page(s)

76-88

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29758235%20AND%20SRC:MED&resulttype=core&format=json

Toxicity of antiviral nucleoside analogs and the human mitochondrial DNA polymerase.

26 March 2020

cites work

1 reference

12 December 2020

Roles of Conformational and Positional Adaptability in Structure-Based Design of TMC125-R165335 (Etravirine) and Related Non-nucleoside Reverse Transcriptase Inhibitors That Are Highly Potent and Effective against Wild-Type and Drug-Resistant HIV-1 V

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12 December 2020

Docosanol: a topical antiviral for herpes labialis

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12 December 2020

The Mechanism of Action of -D-2'-Deoxy-2'-Fluoro-2'-C-Methylcytidine Involves a Second Metabolic Pathway Leading to -D-2'-Deoxy-2'-Fluoro-2'-C-Methyluridine 5'-Triphosphate, a Potent Inhibitor of the Hepatitis C Virus RNA-Dependent RNA Polymerase

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12 December 2020

Adaptation of the hepatitis C virus to cell culture

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12 December 2020

Essential role of platelet-activating factor receptor in the pathogenesis of Dengue virus infection

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12 December 2020

Identification of influenza A nucleoprotein as an antiviral target

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12 December 2020

Celgosivir treatment misfolds dengue virus NS1 protein, induces cellular pro-survival genes and protects against lethal challenge mouse model

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12 December 2020

Ribavirin for the treatment of chronic hepatitis C virus infection: a review of the proposed mechanisms of action

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12 December 2020

Comparing influenza and RSV viral and disease dynamics in experimentally infected adults predicts clinical effectiveness of RSV antivirals.

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12 December 2020

What matters most in commercial success: first-in-class or best-in-class?

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12 December 2020

Association between daily antiretroviral pill burden and treatment adherence, hospitalisation risk, and other healthcare utilisation and costs in a US medicaid population with HIV

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12 December 2020

Efficacy of tecovirimat (ST-246) in nonhuman primates infected with variola virus (Smallpox).

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12 December 2020

Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV

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12 December 2020

Discovery of daclatasvir, a pan-genotypic hepatitis C virus NS5A replication complex inhibitor with potent clinical effect

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12 December 2020

The emerging profile of cross-resistance among the nonnucleoside HIV-1 reverse transcriptase inhibitors

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12 December 2020

Oral GS-5806 activity in a respiratory syncytial virus challenge study.

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12 December 2020

High-content image-based screening of a signal transduction pathway inhibitor small-molecule library against highly pathogenic RNA viruses

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12 December 2020

Preclinical activity of VX-787, a first-in-class, orally bioavailable inhibitor of the influenza virus polymerase PB2 subunit

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12 December 2020

T-cell exhaustion in chronic hepatitis B infection: current knowledge and clinical significance

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12 December 2020

Engineering Cellular Resistance to HIV-1 Infection In Vivo Using a Dual Therapeutic Lentiviral Vector

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12 December 2020

HIV protease inhibitors: a review of molecular selectivity and toxicity

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12 December 2020

Long-acting antiviral agents for HIV treatment

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12 December 2020

Molecular Basis for the Selective Inhibition of Respiratory Syncytial Virus RNA Polymerase by 2'-Fluoro-4'-Chloromethyl-Cytidine Triphosphate

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12 December 2020

Generation and Characterization of ALX-0171, a Potent Novel Therapeutic Nanobody for the Treatment of Respiratory Syncytial Virus Infection

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12 December 2020

Activity of Oral ALS-008176 in a Respiratory Syncytial Virus Challenge Study

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12 December 2020

Experimental Treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial): A Historically Controlled, Single-Arm Proof-of-Concept Trial in Guinea

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12 December 2020

Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys

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12 December 2020

Emerging drugs for the treatment of hepatitis B.

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12 December 2020

A generic screening platform for inhibitors of virus induced cell fusion using cellular electrical impedance

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12 December 2020

Late Ebola virus relapse causing meningoencephalitis: a case report

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12 December 2020

Hepatitis C virus NS3/4a protease inhibitors.

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12 December 2020

HCV NS5A replication complex inhibitors

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12 December 2020

A New Class of Allosteric HIV-1 Integrase Inhibitors Identified by Crystallographic Fragment Screening of the Catalytic Core Domain

1 reference

12 December 2020

A Randomized, Controlled Trial of ZMapp for Ebola Virus Infection

1 reference

12 December 2020

Safety, Tolerability, and Pharmacokinetics of MEDI8897, the Respiratory Syncytial Virus Prefusion F-Targeting Monoclonal Antibody with an Extended Half-Life, in Healthy Adults

1 reference

12 December 2020

Broadly Neutralizing Antibodies for HIV-1 Prevention or Immunotherapy

1 reference

12 December 2020

First Newborn Baby to Receive Experimental Therapies Survives Ebola Virus Disease

1 reference

12 December 2020

Universal antiretroviral regimens: thinking beyond one-pill-once-a-day

1 reference

12 December 2020

HIV drug resistance against strand transfer integrase inhibitors

1 reference

12 December 2020

Capsid Assembly Modulators Have a Dual Mechanism of Action in Primary Human Hepatocytes Infected with Hepatitis B Virus

1 reference

12 December 2020

Preclinical Characterization of PC786, an Inhaled Small-Molecule Respiratory Syncytial Virus L Protein Polymerase Inhibitor

1 reference

12 December 2020

Therapeutic efficacy of a respiratory syncytial virus fusion inhibitor

1 reference

12 December 2020

Antibody therapies for the prevention and treatment of viral infections.

1 reference

12 December 2020

10.1016/J.ANTIVIRAL.2018.05.005

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29758235%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

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