(Q57235374)

English

Influence of Charge Distribution at the Active Site Surface on the Substrate Specificity of Human Neutrophil Protease 3 and Elastase

scientific article published in Journal of Biological Chemistry

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scholarly article

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21 December 2019

Influence of charge distribution at the active site surface on the substrate specificity of human neutrophil protease 3 and elastase. A kinetic and molecular modeling analysis (English)

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21 December 2019

human neutrophil

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based on heuristic

inferred from title

1

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21 December 2019

Nathalie Reuter

4

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21 December 2019

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Eric Hajjar

2

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21 December 2019

Timofey Kalupov

3

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21 December 2019

Michèle Brillard-Bourdet

5

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21 December 2019

Thierry Moreau

6

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21 December 2019

Luiz Juliano

7

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21 December 2019

Francis Gauthier

8

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21 December 2019

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publication date

6 November 2006

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21 December 2019

number of pages

9

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Journal of Biological Chemistry

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21 December 2019

282

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21 December 2019

3

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21 December 2019

1989-1997

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21 December 2019

Proteinase 3. A distinct human polymorphonuclear leukocyte proteinase that produces emphysema in hamsters

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608700200

21 January 2018

The crystal structure of PR3, a neutrophil serine proteinase antigen of Wegener's granulomatosis antibodies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608700200

21 January 2018

Human neutrophil proteinase 3: mapping of the substrate binding site using peptidyl thiobenzyl esters

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608700200

21 January 2018

Discriminating between the activities of human neutrophil elastase and proteinase 3 using serpin-derived fluorogenic substrates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608700200

21 January 2018

Compared action of neutrophil proteinase 3 and elastase on model substrates. Favorable effect of S'-P' interactions on proteinase 3 catalysts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608700200

21 January 2018

Substrate and inhibitor studies on proteinase 3

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608700200

21 January 2018

Competition between elastase and related proteases from human neutrophil for binding to alpha1-protease inhibitor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608700200

21 January 2018

Degradation of native type IV procollagen by human neutrophil elastase. Implications for leukocyte-mediated degradation of basement membranes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608700200

21 January 2018

Down-regulation of a serine protease, myeloblastin, causes growth arrest and differentiation of promyelocytic leukemia cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608700200

21 January 2018

Cleavage of p21waf1 by proteinase-3, a myeloid-specific serine protease, potentiates cell proliferation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608700200

21 January 2018

Cleavage of p21/WAF1/CIP1 by proteinase 3 modulates differentiation of a monocytic cell line. Molecular analysis of the cleavage site.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608700200

21 January 2018

Novel effects of neutrophil-derived proteinase 3 and elastase on the vascular endothelium involve in vivo cleavage of NF-kappaB and proapoptotic changes in JNK, ERK, and p38 MAPK signaling pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608700200

21 January 2018

Proteinase 3 sidesteps caspases and cleaves p21(Waf1/Cip1/Sdi1) to induce endothelial cell apoptosis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608700200

21 January 2018

Wegener's granulomatosis autoantibodies identify a novel diisopropylfluorophosphate-binding protein in the lysosomes of normal human neutrophils

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608700200

21 January 2018

Neutrophil-activating potential of antineutrophil cytoplasm autoantibodies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608700200

21 January 2018

Inspection of the binding sites of proteinase3 for the design of a highly specific substrate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608700200

21 January 2018

All-atom empirical potential for molecular modeling and dynamics studies of proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608700200

21 January 2018

Design and use of highly specific substrates of neutrophil elastase and proteinase 3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608700200

21 January 2018

A novel notch protein, N2N, targeted by neutrophil elastase and implicated in hereditary neutropenia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608700200

21 January 2018

In vitro processing of human tumor necrosis factor-alpha.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608700200

21 January 2018

Converting enzyme-independent release of tumor necrosis factor alpha and IL-1beta from a stimulated human monocytic cell line in the presence of activated neutrophils or purified proteinase 3

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608700200

21 January 2018

Neutrophil serine proteases: potential key regulators of cell signalling during inflammation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608700200

21 January 2018

Immune functions of proteinase 3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608700200

21 January 2018

Mutations in ELA2, encoding neutrophil elastase, define a 21-day biological clock in cyclic haematopoiesis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608700200

21 January 2018

Mutations associated with neutropenia in dogs and humans disrupt intracellular transport of neutrophil elastase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608700200

21 January 2018

Neutrophils: molecules, functions and pathophysiological aspects

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608700200

21 January 2018

Involvement of caspase-1 and caspase-3 in the production and processing of mature human interleukin 18 in monocytic THP.1 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608700200

21 January 2018

Interleukin-18 and interleukin-1 beta: two cytokine substrates for ICE (caspase-1).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608700200

21 January 2018

Internally quenched fluorescent peptide substrates disclose the subsite preferences of human caspases 1, 3, 6, 7 and 8

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608700200

21 January 2018

The structures of caspases-1, -3, -7 and -8 reveal the basis for substrate and inhibitor selectivity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608700200

21 January 2018

On the size of the active site in proteases. I. Papain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608700200

21 January 2018

Identifiers

10.1074/JBC.M608700200

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17088257%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17088257%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

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