(Q57244014)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24463962%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

title

Alternative human liver transcripts of TCF7L2 bind to the gluconeogenesis regulator HNF4α at the protein level (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24463962%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24463962%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Odile Poulain-Godefroy

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24463962%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

François Pattou

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24463962%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Bart Staels

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24463962%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Philippe Froguel

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24463962%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

author name string

Olivier Le Bacquer

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24463962%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Sandrine Caron

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24463962%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Marlène Huyvaert

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24463962%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Audrey Leloire

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24463962%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Cécile Lecoeur

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24463962%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

publication date

26 January 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24463962%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24463962%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

volume

57

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24463962%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24463962%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

page(s)

785-796

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24463962%20AND%20SRC:MED&resulttype=core&format=json

TCF7L2 genetic defect and type 2 diabetes

6 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3154-Z

Reduced insulin exocytosis in human pancreatic β-cells with gene variants linked to type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3154-Z

Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3154-Z

Decreased TCF7L2 protein levels in type 2 diabetes mellitus correlate with downregulation of GIP- and GLP-1 receptors and impaired beta-cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3154-Z

TCF7L2 variant rs7903146 affects the risk of type 2 diabetes by modulating incretin action.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3154-Z

TCF7L2 rs7903146 impairs islet function and morphology in non-diabetic individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3154-Z

Alterations in TCF7L2 expression define its role as a key regulator of glucose metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3154-Z

Unique splicing pattern of the TCF7L2 gene in human pancreatic islets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3154-Z

Alternative splicing of TCF7L2 gene in omental and subcutaneous adipose tissue and risk of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3154-Z

Tissue-specific alternative splicing of TCF7L2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3154-Z

Genotype and tissue-specific effects on alternative splicing of the transcription factor 7-like 2 gene in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3154-Z

TCF7L2 splice variants have distinct effects on beta-cell turnover and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3154-Z

Alternative splicing of Tcf7l2 transcripts generates protein variants with differential promoter-binding and transcriptional activation properties at Wnt/beta-catenin targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3154-Z

An alternative polyadenylation signal in TCF7L2 generates isoforms that inhibit T cell factor/lymphoid-enhancer factor (TCF/LEF)-dependent target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3154-Z

Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3154-Z

Impact of TCF7L2 rs7903146 on insulin secretion and action in young and elderly Danish twins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3154-Z

The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3154-Z

Transcription factor 7-like 2 polymorphism modulates glucose and lipid homeostasis, adipokine profile, and hepatocyte apoptosis in NASH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3154-Z

Transcription dynamics in a physiological process: β-catenin signaling directs liver metabolic zonation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3154-Z

The Wnt signaling pathway effector TCF7L2 is upregulated by insulin and represses hepatic gluconeogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3154-Z

Chromatin occupancy of transcription factor 7-like 2 (TCF7L2) and its role in hepatic glucose metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3154-Z

TCF7L2 modulates glucose homeostasis by regulating CREB- and FoxO1-dependent transcriptional pathway in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3154-Z

Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3154-Z

How cells use pseudopods for persistent movement and navigation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3154-Z

Transcription Factor TCF7L2 Genetic Study in the French Population: Expression in Human -Cells and Adipose Tissue and Strong Association With Type 2 Diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3154-Z

Identification of two regulatory elements within the high mobility group box transcription factor XTCF-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3154-Z

Hepatocyte nuclear factor 4alpha, a key factor for homeostasis, cell architecture, and barrier function of the adult intestinal epithelium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3154-Z

A combination of HNF-4 and Foxo1 is required for reciprocal transcriptional regulation of glucokinase and glucose-6-phosphatase genes in response to fasting and feeding

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3154-Z

Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3154-Z

Efficient double fragmentation ChIP-seq provides nucleotide resolution protein-DNA binding profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3154-Z

Cell type-specific binding patterns reveal that TCF7L2 can be tethered to the genome by association with GATA3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3154-Z

Identification of a promoter-specific transcriptional activation domain at the C terminus of the Wnt effector protein T-cell factor 4

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3154-Z

The human T-cell transcription factor-4 gene: structure, extensive characterization of alternative splicings, and mutational analysis in colorectal cancer cell lines

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24463962

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Wnt signaling regulates hepatic metabolism

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24463962

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Diabetes affects similarly the catalytic subunit and putative glucose-6-phosphate translocase of glucose-6-phosphatase

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24463962

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S00125-013-3154-Z

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24463962%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

1 reference