(Q57369758)

English

Perturbation of membrane microdomains reduces mitogenic signaling and increases susceptibility to apoptosis after T cell receptor stimulation

scientific article published on 01 May 2000

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scholarly article

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6 November 2019

Perturbation of membrane microdomains reduces mitogenic signaling and increases susceptibility to apoptosis after T cell receptor stimulation (English)

1 reference

Europe PubMed Central

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6 November 2019

apoptotic process

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author name string

M Nix

1

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6 November 2019

W Stoffel

2

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6 November 2019

publication date

1 May 2000

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6 November 2019

Cell Death & Differentiation

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6 November 2019

7

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6 November 2019

413-424

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6 November 2019

5

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6 November 2019

https://scigraph.springernature.com/pub.10.1038/sj.cdd.4400666

0 references

Complex complexes: signaling at the TCR.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

A receptor/cytoskeletal movement triggered by costimulation during T cell activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

T lymphocyte costimulation mediated by reorganization of membrane microdomains

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

Upstream-downstream: CD28 cosignaling pathways and T cell function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

Caspases: killer proteases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

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Caspases and caspase inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

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Mitogen-activated protein kinase-mediated Fas apoptotic signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of death receptor signals by cellular FLIP

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

Resistance of cultured peripheral T cells towards activation-induced cell death involves a lack of recruitment of FLICE (MACH/caspase 8) to the CD95 death-inducing signaling complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

Interaction of cholesterol with various glycerophospholipids and sphingomyelin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

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LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

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Engagement of GPI-linked CD48 contributes to TCR signals and cytoskeletal reorganization: a role for lipid rafts in T cell activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

Signal transduction through glyco(sphingo)lipids. Introduction and recent studies on glyco(sphingo)lipid-enriched microdomains.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

Palmitoylation of multiple Src-family kinases at a homologous N-terminal motif

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

Membrane compartmentation is required for efficient T cell activation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

Cholesterol depletion of caveolae causes hyperactivation of extracellular signal-related kinase (ERK).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

Acid sphingomyelinase-deficient mice mimic the neurovisceral form of human lysosomal storage disease (Niemann-Pick disease).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

Ceramide-independent CD28 and TCR signaling but reduced IL-2 secretion in T cells of acid sphingomyelinase-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

Subcellular fractionation of rat liver.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

Decreased membrane fluidity and unsaturated fatty acids in Niemann-Pick disease type C fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

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Sorting of an internalized plasma membrane lipid between recycling and degradative pathways in normal and Niemann-Pick, type A fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

Functions of lipid rafts in biological membranes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification, sequence, and expression of caveolin-2 defines a caveolin gene family

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell surface trafficking of Fas: a rapid mechanism of p53-mediated apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

Substrate specificities of caspase family proteases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

Monitoring of relative mitochondrial membrane potential in living cells by fluorescence microscopy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitogen-activated protein kinase kinase antagonized fas-associated death domain protein-mediated apoptosis by induced FLICE-inhibitory protein expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of c-FLIP in modulation of CD95-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of intracellular ceramide content in B16 melanoma cells. Biological implications of ceramide glycosylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

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Immunocytochemical visualization of coated pits and vesicles in human fibroblasts: Relation to low density lipoprotein receptor distribution

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

Ceramides in phospholipid membranes: effects on bilayer stability and transition to nonlamellar phases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

Ceramides perturb the structure of phosphatidylcholine bilayers and modulate the activity of phospholipase A2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

Homeostasis of cell-surface glycosphingolipid content in B16 melanoma cells. Evidence revealed by an endoglycoceramidase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

Two sterol regulatory element-like sequences mediate up-regulation of caveolin gene transcription in response to low density lipoprotein free cholesterol

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

Plasma membrane caveolae mediate the efflux of cellular free cholesterol

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

Oligomerization of VIP21-caveolin in vitro is stabilized by long chain fatty acylation or cholesterol

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

Trafficking of an acylated cytosolic protein: newly synthesized p56(lck) travels to the plasma membrane via the exocytic pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

S-acylation of LCK protein tyrosine kinase is essential for its signalling function in T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

Palmitoylation of p59fyn is reversible and sufficient for plasma membrane association

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

Myristylation and palmitylation of Src family members: the fats of the matter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

Multiple features of the p59fyn src homology 4 domain define a motif for immune-receptor tyrosine-based activation motif (ITAM) binding and for plasma membrane localization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

Early signal transduction by the antigen receptor without commitment to T cell activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

JNK is involved in signal integration during costimulation of T lymphocytes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

inferred from DOI database lookup

Apoptosis by death factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

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Tumor necrosis factor (TNF)-mediated kinase cascades: bifurcation of nuclear factor-kappaB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

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Modulation of life and death by the TNF receptor superfamily

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400666

7 January 2021

based on heuristic

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Identifiers

10.1038/SJ.CDD.4400666

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10800075%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10800075%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

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