(Q57372619)

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A Chemogenomic Screen inSaccharomyces cerevisiaeUncovers a Primary Role for the Mitochondria in Farnesol Toxicity and Its Regulation by the Pkc1 Pathway

scientific article published in Journal of Biological Chemistry

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17164236%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

A chemogenomic screen in Saccharomyces cerevisiae uncovers a primary role for the mitochondria in farnesol toxicity and its regulation by the Pkc1 pathway (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17164236%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

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Saccharomyces cerevisiae

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1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17164236%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

author name string

Kendra Macdonald

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17164236%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

Christopher R McMaster

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17164236%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

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12 December 2006

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17164236%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

Journal of Biological Chemistry

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17164236%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

282

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17164236%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

7

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17164236%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

4868-4874

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17164236%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

Differences in sensitivity to farnesol toxicity between neoplastically- and non-neoplastically-derived cells in culture

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610575200

21 January 2018

Preferential induction of apoptosis of leukaemic cells by farnesol

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610575200

21 January 2018

Inhibition of phosphatidylcholine biosynthesis following induction of apoptosis in HL-60 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610575200

21 January 2018

Uncoupling farnesol-induced apoptosis from its inhibition of phosphatidylcholine synthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610575200

21 January 2018

Enhanced apoptosis through farnesol inhibition of phospholipase D signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610575200

21 January 2018

Divergence and complexities in DAG signaling: looking beyond PKC

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610575200

21 January 2018

Yeast protein kinases and the RHO1 exchange factor TUS1 are novel components of the cell integrity pathway in yeast

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610575200

21 January 2018

Pkc1 and the upstream elements of the cell integrity pathway in Saccharomyces cerevisiae, Rom2 and Mtl1, are required for cellular responses to oxidative stress

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610575200

21 January 2018

Studying phospholipid metabolism using yeast systematic and chemical genetics

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610575200

21 January 2018

The GRID: the General Repository for Interaction Datasets

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610575200

21 January 2018

A role for the Pkc1p/Mpk1p kinase cascade in the morphogenesis checkpoint

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610575200

21 January 2018

Cytotoxicity of an Anti-cancer Lysophospholipid through Selective Modification of Lipid Raft Composition

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610575200

21 January 2018

Chemical genetics: tailoring tools for cell biology

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610575200

21 January 2018

Structure at 2.3 A resolution of the cytochrome bc(1) complex from the yeast Saccharomyces cerevisiae co-crystallized with an antibody Fv fragment

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610575200

21 January 2018

The role of various domains of the iron-sulfur protein in the assembly and activity of the cytochrome bc1 complex of yeast mitochondria

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610575200

21 January 2018

Complex III releases superoxide to both sides of the inner mitochondrial membrane

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610575200

21 January 2018

Superoxide dismutase activity is essential for stationary phase survival in Saccharomyces cerevisiae. Mitochondrial production of toxic oxygen species in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610575200

21 January 2018

The p21-activated protein kinase-related kinase Cla4 is a coincidence detector of signaling by Cdc42 and phosphatidylinositol 4-phosphate.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610575200

21 January 2018

Cell wall integrity signaling in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610575200

21 January 2018

Caspase processing and nuclear export of CTP:phosphocholine cytidylyltransferase alpha during farnesol-induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610575200

21 January 2018

Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610575200

21 January 2018

Structure of the yeast cytochrome bc1 complex with a hydroxyquinone anion Qo site inhibitor bound

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610575200

21 January 2018

The ubiquinol/bc1 redox couple regulates mitochondrial oxygen radical formation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610575200

21 January 2018

Intracellular generation of reactive oxygen species by mitochondria

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610575200

21 January 2018

Subcellular localization of the yeast proteome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610575200

21 January 2018

Global analysis of protein localization in budding yeast

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610575200

21 January 2018

Identifiers

10.1074/JBC.M610575200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17164236%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17164236%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

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