(Q57605783)

English

In obese and non-obese adults, the cis-regulatory rs361072 promoter variant of PIK3CB is associated with insulin resistance not with type 2 diabetes

scholarly article by Karine Clément et al published March 2009 in Molecular Genetics and Metabolism

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scholarly article

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In obese and non-obese adults, the cis-regulatory rs361072 promoter variant of PIK3CB is associated with insulin resistance not with type 2 diabetes (English)

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type 2 diabetes

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based on heuristic

inferred from title

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based on heuristic

inferred from title

insulin resistance

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based on heuristic

inferred from title

Aline Meirhaeghe

object named as

Aline Meirhaeghe

3

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Christian Boitard

object named as

Christian Boitard

7

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Jean Ferrières

object named as

Jean Ferrieres

5

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Philippe Amouyel

object named as

Philippe Amouyel

8

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Catherine Le Stunff

object named as

Catherine Le Stunff

2

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Karine Clément

1

object named as

Karine Clément

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Pierre Bougnères

9

object named as

Pierre Bougnères

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author name string

Agnès Dechartres

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Arnaud Basdevant

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publication date

March 2009

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Molecular Genetics and Metabolism

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96

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3

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129-132

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Association analysis indicates that a variant GATA-binding site in the PIK3CB promoter is a Cis-acting expression quantitative trait locus for this gene and attenuates insulin resistance in obese children

1 reference

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Beta-cell dysfunction, rather than insulin insensitivity, is the primary defect in familial type 2 diabetes.

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Contributions of beta-cell dysfunction and insulin resistance to the pathogenesis of impaired glucose tolerance and impaired fasting glucose

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The Eating Inventory and body adiposity from leanness to massive obesity: a study of 2509 adults.

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Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

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Function of GATA transcription factors in preadipocyte-adipocyte transition

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Leptin regulates insulin sensitivity via phosphatidylinositol-3-OH kinase signaling in mediobasal hypothalamic neurons.

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Effect of insulin resistance, dyslipidemia, and intra-abdominal adiposity on the development of cardiovascular disease and diabetes mellitus

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Gene encoding the catalytic subunit p110beta of human phosphatidylinositol 3-kinase: cloning, genomic structure, and screening for variants in patients with type 2 diabetes

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Nonketotic diabetes mellitus: insulin deficiency or insulin resistance?

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10.1016/J.YMGME.2008.11.160

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