(Q57667575)

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The multiple sclerosis whole blood mRNA transcriptome and genetic associations indicate dysregulation of specific T cell pathways in pathogenesis

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scholarly article

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The multiple sclerosis whole blood mRNA transcriptome and genetic associations indicate dysregulation of specific T cell pathways in pathogenesis (English)

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multiple sclerosis

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1 reference

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inferred from title

object named as

Fiona C. McKay

2

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object named as

Carlos Riveros

4

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object named as

Pablo Moscato

14

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object named as

Mark Slee

19

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Allan G. Kermode

object named as

Allan Kermode

31

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Trevor Kilpatrick

object named as

Trevor Kilpatrick

22

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Matthew A. Brown

object named as

Matthew Brown

10

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7

object named as

Steve Vucic

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author name string

Kaushal S. Gandhi

1

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Mathew Cox

3

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Nicola Armstrong

5

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Robert N. Heard

6

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David W. Williams

8

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Jim Stankovich

9

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Patrick Danoy

11

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Graeme J. Stewart

12

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Simon Broadley

13

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Jeannette Lechner-Scott

15

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Rodney J. Scott

16

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David R. Booth

17

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Lyn Griffiths

18

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Sharon Browning

20

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Brian L. Browning

21

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Justin Rubio

23

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Victoria Perreau

24

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Helmut Butzkeuven

25

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Mary Tanner

26

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Jim Wiley

27

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Simon Foote

28

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Jim Stankovich

29

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Bruce Taylor

30

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Bill Carroll

32

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Melanie Bahlo

33

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publication date

27 February 2010

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Human Molecular Genetics

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19

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11

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2134-2143

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The genetics of multiple sclerosis: SNPs to pathways to pathogenesis

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ090

21 January 2018

Risk alleles for multiple sclerosis identified by a genomewide study

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https://api.crossref.org/works/10.1093%2FHMG%2FDDQ090

21 January 2018

Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ090

21 January 2018

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ090

21 January 2018

Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ090

21 January 2018

Relative impact of nucleotide and copy number variation on gene expression phenotypes

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ090

21 January 2018

Mapping the genetic architecture of gene expression in human liver

1 reference

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21 January 2018

Genetics of gene expression and its effect on disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ090

21 January 2018

Characterizing the mechanisms of progression in multiple sclerosis: evidence and new hypotheses for future directions

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ090

21 January 2018

NF-kappa B, a potential therapeutic target for the treatment of multiple sclerosis

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ090

21 January 2018

Assessment of two methods for handling blood in collection tubes with RNA stabilizing agent for surveillance of gene expression profiles with high density microarrays.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ090

21 January 2018

Individuality and variation in gene expression patterns in human blood

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ090

21 January 2018

Significance analysis of microarrays applied to the ionizing radiation response

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ090

21 January 2018

Immune response in silico (IRIS): immune-specific genes identified from a compendium of microarray expression data.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ090

21 January 2018

The Immunological Genome Project: networks of gene expression in immune cells.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ090

21 January 2018

Aberrant transcriptional regulatory network in T cells of multiple sclerosis.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ090

21 January 2018

Cell-type specific gene expression profiles of leukocytes in human peripheral blood

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ090

21 January 2018

Comparative analysis of transcriptional profiling of CD3+, CD4+ and CD8+ T cells identifies novel immune response players in T-cell activation

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ090

21 January 2018

A genome-wide association study of global gene expression

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ090

21 January 2018

Gene expression profiles reveal homeostatic dynamics during interferon-beta therapy in multiple sclerosis

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ090

21 January 2018

Profiles of gene expression in human autoimmune disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ090

21 January 2018

Abnormal Tr1 differentiation in multiple sclerosis

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ090

21 January 2018

Multiple sclerosis and regulatory T cells

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ090

21 January 2018

Cytometric profiling in multiple sclerosis uncovers patient population structure and a reduction of CD8low cells

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ090

21 January 2018

CD40-CD40 ligand interactions in oxidative stress, inflammation and vascular disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ090

21 January 2018

Autoimmunity in hyper-IgM syndrome.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ090

21 January 2018

Common variants at CD40 and other loci confer risk of rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ090

21 January 2018

Not always the bad guys: B cells as regulators of autoimmune pathology

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ090

21 January 2018

Friendly and dangerous signals: is the tissue in control?

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ090

21 January 2018

Differential responses of human B-lymphocyte subpopulations to graded levels of CD40-CD154 interaction

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ090

21 January 2018

Genomewide association studies and human disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ090

21 January 2018

The expanding genetic overlap between multiple sclerosis and type I diabetes

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ090

21 January 2018

Autoimmune diseases: insights from genome-wide association studies

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ090

21 January 2018

IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ090

21 January 2018

New diagnostic criteria for multiple sclerosis: guidelines for research protocols

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ090

21 January 2018

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ090

21 January 2018

Gene expression and genotyping studies implicate the interleukin 7 receptor in the pathogenesis of primary progressive multiple sclerosis

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ090

21 January 2018

Identifiers

10.1093/HMG/DDQ090

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