(Q57672125)

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Paracetamol increases sensitivity to ultraviolet (UV) irradiation, delays repair of the UNG-gene and recovery of RNA synthesis in HaCaT cells

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9566729%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

Paracetamol increases sensitivity to ultraviolet (UV) irradiation, delays repair of the UNG-gene and recovery of RNA synthesis in HaCaT cells (English)

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11 November 2019

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B Alm

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11 November 2019

C Skjelbred

3

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11 November 2019

P A Aas

4

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11 November 2019

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1 March 1998

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11 November 2019

Chemico-biological Interactions

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11 November 2019

110

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11 November 2019

1-2

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11 November 2019

123-136

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11 November 2019

Genotoxic effects of paracetamol in V79 Chinese hamster cells

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Inhibition of replicative DNA synthesis by paracetamol in V79 Chinese hamster cells

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Paracetamol inhibits replicative DNA synthesis and induces sister chromatid exchange and chromosomal aberrations by inhibition of ribonucleotide reductase

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Mutagenicity studies on paracetamol in human volunteers II. Unscheduled DNA synthesis and micronucleus test

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Increased frequency of sister-chromatid exchange and chromatid breaks in lymphocytes after treatment of human volunteers with therapeutic doses of paracetamol

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Paracetamol inhibits UV-induced DNA repair in resting human mononuclear blood cells in vitro

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Inhibitory effects of paracetamol on DNA repair in mammalian cells

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International Commission for Protection Against Environmental Mutagens and Carcinogens. Approaches to SAR in carcinogenesis and mutagenesis. Prediction of carcinogenicity/mutagenicity using MULTI-CASE.

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Additional effect of acetaminophen on the mutagenicity and clastogenicity of N-methyl-N'-nitro-N-nitrosoguanidine in cultured Chinese hamster CHO-Kl cells

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Absence of mutagenic activity of benorylate, paracetamol and aspirin in the Salmonella/mammalian microsome test

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Validation and comparative studies on 180 chemicals with S. typhimurium strains and V79 Chinese hamster cells in the presence of various metabolizing systems

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A comparative analysis of data on the clastogenicity of 951 chemical substances tested in mammalian cell cultures

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Nucleotide excision repair. II: From yeast to mammals

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Repair of UV-damaged DNA by mammalian cells and Saccharomyces cerevisiae

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DNA repair helicase: a component of BTF2 (TFIIH) basic transcription factor

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Dual role of TFIIH in DNA excision repair and in transcription by RNA polymerase II

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Human uracil-DNA glycosylase gene: sequence organization, methylation pattern, and mapping to chromosome 12q23-q24.1

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7 January 2021

Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNG gene

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New bacteriophage vectors for the large scale production of single stranded insert DNA

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Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

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Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene

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Preferential repair of DNA damage on the transcribed strand of the human metallothionein genes requires RNA polymerase II.

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Repair of cyclobutane pyrimidine dimers in the O6-methylguanine-DNA methyltransferase (MGMT) gene of MGMT proficient and deficient human cell lines and comparison with the repair of other genes and a repressed X-chromosomal locus

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7 January 2021

A block to elongation is largely responsible for decreased transcription of c-myc in differentiated HL60 cells

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Two distinct mechanisms of transcriptional control operate on c-myc during differentiation of HL60 cells

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The acute effects of ultraviolet-B radiation on c-myc and c-Ha ras expression in normal human epidermis

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Acetaminophen protects human erythrocytes against oxidative stress

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Antioxidant effect of acetaminophen in rat liver

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The effect of paracetamol on oxidative damage in human peripheral lymphocytes

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Paracetamol, 3-monoalkyl- and 3,5-dialkyl-substituted derivatives. Antioxidant activity and relationship between lipid peroxidation and cytotoxicity

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Li-Fraumeni syndrome fibroblasts homozygous for p53 mutations are deficient in global DNA repair but exhibit normal transcription-coupled repair and enhanced UV resistance

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Expression of wild-type p53 is required for efficient global genomic nucleotide excision repair in UV-irradiated human fibroblasts

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p53 mutations in human immortalized epithelial cell lines

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The covalent binding of acetaminophen to protein. Evidence for cysteine residues as major sites of arylation in vitro

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Acetaminophen activation by human liver cytochromes P450IIE1 and P450IA2

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Antioxidant and redox regulation of gene transcription

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Identifiers

10.1016/S0009-2797(98)00002-7

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9566729%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9566729%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

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