(Q57707242)

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Regulation of the α1-Antitrypsin Gene and a Disease-associated Mutation in a Related Enhancer Sequence

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title

Regulation of the α1-Antitrypsin Gene and a Disease-associated Mutation in a Related Enhancer Sequence (English)

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K. Morgan

2

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author name string

Noor A. Kalsheker

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1

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language of work or name

English

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publication date

December 1994

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published in

American Journal of Respiratory and Critical Care Medicine

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volume

150

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issue

6_pt_2

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page(s)

S183-S189

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cites work

Alpha 1-antitrypsin deficiency, emphysema, and liver disease. Genetic basis and strategies for therapy

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Evolution at two levels in humans and chimpanzees

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Spontaneous expression of the c-sis gene and release of a platelet-derived growth factorlike molecule by human alveolar macrophages

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Exclusion of an exon in monocyte alpha-1-antitrypsin mRNA after stimulation of U937 cells by interleukin-6.

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Interferon beta 2/interleukin 6 modulates synthesis of alpha 1-antitrypsin in human mononuclear phagocytes and in human hepatoma cells

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Tissue-specific expression of the human alpha 1-antitrypsin gene is controlled by multiple cis-regulatory elements

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Cell-specific expression of a transfected human alpha 1-antitrypsin gene

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A negative regulatory element in the promoter of the human alpha 1-antitrypsin gene

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The characterization of a mutation of the 3' flanking sequence of the alpha 1-antitrypsin gene commonly associated with chronic obstructive airways disease

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Compilation of vertebrate-encoded transcription factors

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Hypoxia-inducible nuclear factors bind to an enhancer element located 3' to the human erythropoietin gene

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Point mutation in a 3' flanking sequence of the alpha-1-antitrypsin gene associated with chronic respiratory disease occurs in a regulatory sequence

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21 January 2018

Immunolocalization of elastase in human emphysematous lungs

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The two C/EBP isoforms, IL-6DBP/NF-IL6 and C/EBP delta/NF-IL6 beta, are induced by IL-6 to promote acute phase gene transcription via different mechanisms.

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Identifiers

DOI

10.1164/AJRCCM/150.6_PT_2.S183

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PubMed publication ID

7952657

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(Q57707242)

Regulation of the α1-Antitrypsin Gene and a Disease-associated Mutation in a Related Enhancer Sequence

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