(Q57851674)

1

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Matteo Pappalardo

2

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Francesco Attanasio

3

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Danilo Milardi

4

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Carmelo La Rosa

5

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Domenico M. Grasso

Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus

6

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publication date

2010

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published in

New Journal of Chemistry

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volume

34

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issue

2

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page(s)

200-207

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cites work

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Models of amyloid seeding in Alzheimer's disease and scrapie: mechanistic truths and physiological consequences of the time-dependent solubility of amyloid proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

21 January 2018

Prion Protein Biology

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Islet amyloid polypeptide (IAPP):cDNA cloning and identification of an amyloidogenic region associated with the species-specific occurrence of age-related diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

The mechanism of islet amyloid polypeptide toxicity is membrane disruption by intermediate-sized toxic amyloid particles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

The aggregation potential of human amylin determines its cytotoxicity towards islet beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Induction of negative curvature as a mechanism of cell toxicity by amyloidogenic peptides: the case of islet amyloid polypeptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Three-Dimensional Structure and Orientation of Rat Islet Amyloid Polypeptide Protein in a Membrane Environment by Solution NMR Spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

A single mutation in the nonamyloidogenic region of islet amyloid polypeptide greatly reduces toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Are amyloid diseases caused by protein aggregates that mimic bacterial pore-forming toxins?

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Controlling amyloid beta-peptide fibril formation with protease-stable ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Design of peptide-based inhibitors of human islet amyloid polypeptide fibrillogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Structure-based design and study of non-amyloidogenic, double N-methylated IAPP amyloid core sequences as inhibitors of IAPP amyloid formation and cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Amyloid fibrils formed from a segment of the pancreatic islet amyloid protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Conformational preferences of the amylin nucleation site in SDS micelles: an NMR study

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Identification of a penta- and hexapeptide of islet amyloid polypeptide (IAPP) with amyloidogenic and cytotoxic properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Unique identification of supramolecular structures in amyloid fibrils by solid-state NMR spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Analysis of amylin cleavage products provides new insights into the amyloidogenic region of human amylin

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Identification of a novel human islet amyloid polypeptide beta-sheet domain and factors influencing fibrillogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Identification of minimal peptide sequences in the (8-20) domain of human islet amyloid polypeptide involved in fibrillogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Prediction of sequence-dependent and mutational effects on the aggregation of peptides and proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

A molecular dynamics approach to the structural characterization of amyloid aggregation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Molecular dynamics simulations of Alzheimer's beta-amyloid protofilaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Calcium-activated membrane interaction of the islet amyloid polypeptide: implications in the pathogenesis of type II diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

DSC study of the interaction of the prion peptide PrP106–126 with artificial membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Small-volume extrusion apparatus for preparation of large, unilamellar vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

CHARMM: A program for macromolecular energy, minimization, and dynamics calculations

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

The role of side-chain interactions in the early steps of aggregation: Molecular dynamics simulations of an amyloid-forming peptide from the yeast prion Sup35

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Effective energy function for proteins in solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Discrimination of the native from misfolded protein models with an energy function including implicit solvation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Effective energy function for proteins in lipid membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Perturbation of the hydrophobic core of lipid bilayers by the human antimicrobial peptide LL-37.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Environmental Effects on a Prion's Helix II Domain: Copper(II) and Membrane Interactions with PrP180–193 and Its Analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Structures of rat and human islet amyloid polypeptide IAPP(1-19) in micelles by NMR spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Islet amyloid: a complication of islet dysfunction or an aetiological factor in Type 2 diabetes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Role of islet amyloid in type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Long-term treatment with rosiglitazone and metformin reduces the extent of, but does not prevent, islet amyloid deposition in mice expressing the gene for human islet amyloid polypeptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Environmental factors differently affect human and rat IAPP: conformational preferences and membrane interactions of IAPP17-29 peptide derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Properties of ternary phospholipid/dimethyl sulfoxide/water systems at low temperatures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

The mechanism of insulin action on islet amyloid polypeptide fiber formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Group additive contributions to the alcohol-induced alpha-helix formation of melittin: implication for the mechanism of the alcohol effects on proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Molecular basis for dimethylsulfoxide (DMSO) action on lipid membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Methylene blue inhibits amyloid Abeta oligomerization by promoting fibrillization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Small molecule inhibitors of aggregation indicate that amyloid beta oligomerization and fibrillization pathways are independent and distinct

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Membrane fragmentation by an amyloidogenic fragment of human Islet Amyloid Polypeptide detected by solid-state NMR spectroscopy of membrane nanotubes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Fiber-dependent amyloid formation as catalysis of an existing reaction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Atomic structure of the cross-β spine of islet amyloid polypeptide (amylin)

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Amyloid fiber formation and membrane disruption are separate processes localized in two distinct regions of IAPP, the type-2-diabetes-related peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G

Prediction of the Absolute Aggregation Rates of Amyloidogenic Polypeptide Chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FB9NJ00253G