(Q58033381)

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Channeling efficiency in the bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase domain: the effects of site-directed mutagenesis of NADP binding residues

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scholarly article

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31 October 2019

Channeling efficiency in the bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase domain: the effects of site-directed mutagenesis of NADP binding residues (English)

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31 October 2019

author name string

M Allaire

2

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31 October 2019

R E MacKenzie

4

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31 October 2019

publication date

1 June 2000

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31 October 2019

Biochimica et Biophysica Acta

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31 October 2019

1479

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31 October 2019

59-68

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31 October 2019

1-2

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31 October 2019

Binding and interconversion of tetrahydrofolates at a single site in the bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase

1 reference

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7 January 2021

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Binding of the 2',5'-ADP subsite stimulates cyclohydrolase activity of human NADP(+)-dependent methylenetetrahydrofolate dehydrogenase/cyclohydrolase

1 reference

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7 January 2021

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Methylenetetrahydrofolate dehydrogenase, methenyltetrahydrofolate cyclohydrolase and formyltetrahydrofolate synthetase from porcine liver. Isolation of a dehydrogenase-cyclohydrolase fragment from the multifunctional enzyme

1 reference

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Methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase-formyltetrahydrofolate synthetase from porcine liver. Interaction between the dehydrogenase and cyclohydrolase activities of the multifunctional enzyme

1 reference

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7 January 2021

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Methenyltetrahydrofolate cyclohydrolase is rate limiting for the enzymatic conversion of 10-formyltetrahydrofolate to 5,10-methylenetetrahydrofolate in bifunctional dehydrogenase-cyclohydrolase enzymes

1 reference

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Crystallization of the bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase domain of the human trifunctional enzyme

1 reference

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The 3-D structure of a folate-dependent dehydrogenase/cyclohydrolase bifunctional enzyme at 1.5 A resolution

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7 January 2021

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Involvement of two basic residues (Lys-270 and Arg-276) of human liver 3 alpha-hydroxysteroid dehydrogenase in NADP(H) binding and activation by sulphobromophthalein: site-directed mutagenesis and kinetic analysis

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Phosphorus-31 nuclear magnetic resonance studies on coenzyme binding and specificity in glyceraldehyde-3-phosphate dehydrogenase

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AFAP-120. A variant form of the Src SH2/SH3-binding partner AFAP-110 is detected in brain and contains a novel internal sequence which binds to a 67-kDa protein

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A study of the binding of NADP coenzymes to dihydrofolate reductase by raman difference spectroscopy.

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Formiminotransferase-cyclodeaminase from procine liver. Purification and physical properties of the enzyme complex

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DNA sequence changes of mutations in the histidine operon control region that decrease attenuation

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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Methylenetetrahydrofolate dehydrogenase-cyclohydrolase from Photobacterium phosphoreum shares properties with a mammalian mitochondrial homologue

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Interaction of pyridine nucleotide substrates with Escherichia coli dihydrodipicolinate reductase: thermodynamic and structural analysis of binary complexes

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Involvement of two basic residues (Lys-17 and Arg-39) of mouse lung carbonyl reductase in NADP(H)-binding and fatty acid activation: site-directed mutagenesis and kinetic analyses

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7 January 2021

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Interaction with arginine 597 of NADPH-cytochrome P-450 oxidoreductase is a primary source of the uniform binding energy used to discriminate between NADPH and NADH

1 reference

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7 January 2021

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Expression of active domains of a human folate-dependent trifunctional enzyme in Escherichia coli

1 reference

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MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

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Identifiers

10.1016/S0167-4838(00)00058-3

1 reference

Europe PubMed Central

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31 October 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11004530%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

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