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Chemoenzymatic Synthesis of (Protected) Psymberic Acid
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title
Chemoenzymatic Synthesis of (Protected) Psymberic Acid
(English)
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author
Jörg Pietruszka
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1
object named as
Jörg Pietruszka
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author name string
Robert Christian Simon
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2
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publication date
July 2009
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published in
European Journal of Organic Chemistry
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volume
2009
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issue
21
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page(s)
3628-3634
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cites work
Psymberin, a potent sponge-derived cytotoxin from Psammocinia distantly related to the pederin family
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Antineoplastic agents. 520. Isolation and structure of irciniastatins A and B from the Indo-Pacific marine sponge Ircinia ramosa.
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Revisiting the sponge sources, stereostructure, and biological activity of cyclocinamide a
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Synthesis and complete stereochemical assignment of psymberin/irciniastatin A
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The total synthesis of psymberin
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Total synthesis of (+)-psymberin (irciniastatin A): catalytic reagent control as the strategic cornerstone
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Configuration of the psymberin amide side chain
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Stereochemical assignment of the C1-C6 fragment of psymberin by synthesis and natural product degradation.
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Multicomponent approach to the synthesis of oxidized amides through nitrile hydrozirconation
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Catalytic asymmetric addition of alcohols to imines: enantioselective preparation of chiral N,O-aminals
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Concise and stereoselective synthesis of the N7-C25 fragment of psymberin
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A formal synthesis of psymberin
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Synthesis of psymberin analogues: probing a functional correlation with the pederin/mycalamide family of natural products
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The discovery of potent antitumor agent C11-deoxypsymberin/irciniastatin A: total synthesis and biology of advanced psymberin analogs.
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Preparation of enantiopure butane-2,3-diacetals of glycolic acid and alkylation reactions leading to α-hydroxyacid and amide derivatives
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Studies on the generation of enolate anions from butane-2,3-diacetal protected glycolic acid derivatives and subsequent highly diastereoselective coupling reactions with aldehydes and acid chlorides
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A fascination with 1,2-diacetals.
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Readily accessible 12-I-5 oxidant for the conversion of primary and secondary alcohols to aldehydes and ketones
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A useful 12-I-5 triacetoxyperiodinane (the Dess-Martin periodinane) for the selective oxidation of primary or secondary alcohols and a variety of related 12-I-5 species
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Identifiers
DOI
10.1002/EJOC.200900292
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