(Q58072656)

2

object named as

Shina C. L. Kamerlin

0 references

Arieh Warshel

5

object named as

Arieh Warshel

0 references

author name string

Abdulfattah Alkherraz

1

0 references

Guoqiang Feng

3

0 references

Qaiser I. Sheikh

The rate of hydrolysis of phosphomonoester dianions and the exceptional catalytic proficiencies of protein and inositol phosphatases

4

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publication date

2010

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published in

Faraday Discussions

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volume

145

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page(s)

281-299

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cites work

1 reference

Electrostatic basis for enzyme catalysis

21 January 2018

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Enzymatic transition state theory and transition state analogue design

21 January 2018

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Phosphonamidates as transition-state analogue inhibitors of thermolysin.

21 January 2018

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Binding Energy and Catalysis: The Implications for Transition-State Analogs and Catalytic Antibodies.

21 January 2018

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On the generation of catalytic antibodies by transition state analogues.

21 January 2018

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Electrostatic contributions to binding of transition state analogues can be very different from the corresponding contributions to catalysis: phenolates binding to the oxyanion hole of ketosteroid isomerase

21 January 2018

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Alkaline phosphatase mono- and diesterase reactions: comparative transition state analysis

21 January 2018

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Functional interrelationships in the alkaline phosphatase superfamily: phosphodiesterase activity of Escherichia coli alkaline phosphatase

21 January 2018

1 reference

The nature of the transition state for enzyme-catalyzed phosphoryl transfer. Hydrolysis of O-aryl phosphorothioates by alkaline phosphatase

21 January 2018

1 reference

On the interpretation of the observed linear free energy relationship in phosphate hydrolysis: a thorough computational study of phosphate diester hydrolysis in solution

21 January 2018

1 reference

Structure/function correlations of proteins using MM, QM/MM, and related approaches: methods, concepts, pitfalls, and current progress

21 January 2018

1 reference

Dynamical contributions to enzyme catalysis: critical tests of a popular hypothesis

21 January 2018

1 reference

A primer for the Bema Hapothle. An empirical approach to the characterization of changing transition-state structures

21 January 2018

1 reference

Associative versus dissociative mechanisms of phosphate monoester hydrolysis: on the interpretation of activation entropies

21 January 2018

1 reference

Are mixed explicit/implicit solvation models reliable for studying phosphate hydrolysis? A comparative study of continuum, explicit and mixed solvation models

21 January 2018

1 reference

Dineopentyl phosphate hydrolysis: evidence for stepwise water attack

21 January 2018

1 reference

The role of metal ions in phosphate ester hydrolysis.

21 January 2018

1 reference

On the mechanism of hydrolysis of phosphate monoesters dianions in solutions and proteins

21 January 2018

1 reference

Supermolecule density functional calculations suggest a key role for solvent in alkaline hydrolysis of p-nitrophenyl phosphate.

21 January 2018

1 reference

Modeling electrostatic effects in proteins

21 January 2018

1 reference

Density-functional thermochemistry. III. The role of exact exchange

21 January 2018

1 reference

Quantum Calculation of Molecular Energies and Energy Gradients in Solution by a Conductor Solvent Model

21 January 2018

1 reference

COSMO: a new approach to dielectric screening in solvents with explicit expressions for the screening energy and its gradient

21 January 2018

1 reference

The IEF version of the PCM solvation method: an overview of a new method addressed to study molecular solutes at the QM ab initio level

21 January 2018

1 reference

New developments in the polarizable continuum model for quantum mechanical and classical calculations on molecules in solution

21 January 2018

1 reference

The calculation of small molecular interactions by the differences of separate total energies. Some procedures with reduced errors

21 January 2018

1 reference

What are the roles of substrate-assisted catalysis and proximity effects in peptide bond formation by the ribosome?

21 January 2018

1 reference

Kinetic isotope effects for alkaline phosphatase reactions: implications for the role of active-site metal ions in catalysis

21 January 2018

1 reference

Use of site-directed mutagenesis to elucidate the role of arginine-166 in the catalytic mechanism of alkaline phosphatase

21 January 2018

1 reference

Mechanistic alternatives in phosphate monoester hydrolysis: what conclusions can be drawn from available experimental data?

21 January 2018

1 reference

Phosphoryl group transfer: evolution of a catalytic scaffold

21 January 2018

1 reference

Alkaline phosphatase revisited: hydrolysis of alkyl phosphates

21 January 2018

1 reference

Efficient catalytic promiscuity in an enzyme superfamily: an arylsulfatase shows a rate acceleration of 10(13) for phosphate monoester hydrolysis

21 January 2018

1 reference

Mechanistic study of protein phosphatase-1 (PP1), a catalytically promiscuous enzyme

21 January 2018

1 reference

A superfamily of metalloenzymes unifies phosphopentomutase and cofactor-independent phosphoglycerate mutase with alkaline phosphatases and sulfatases

21 January 2018

1 reference

Conserved core structure and active site residues in alkaline phosphatase superfamily enzymes

21 January 2018

1 reference

Structural and catalytic similarities between nucleotide pyrophosphatases/phosphodiesterases and alkaline phosphatases

21 January 2018

1 reference

Testing Geometrical Discrimination within an Enzyme Active Site: Constrained Hydrogen Bonding in the Ketosteroid Isomerase Oxyanion Hole

21 January 2018

1 reference

A "moonlighting" dizinc aminopeptidase from Streptomyces griseus: mechanisms for peptide hydrolysis and the 4 x 10(10)-fold acceleration of the alternative phosphodiester hydrolysis

21 January 2018

1 reference

Different transition-state structures for the reactions of beta-lactams and analogous beta-sultams with serine beta-lactamases

21 January 2018

1 reference

Acylation versus sulfonylation in the inhibition of elastase by 3-oxo-beta-sultams

21 January 2018

1 reference

Reactivity of Phosphate Diesters Doubly Coordinated to a Dinuclear Cobalt(III) Complex: Dependence of the Reactivity on the Basicity of the Leaving Group

21 January 2018

1 reference