(Q58121844)

English

Porphyrin-Based SOD Mimic MnTnBu OE -2-PyP Inhibits Mechanisms of Aortic Valve Remodeling in Human and Murine Models of Aortic Valve Sclerosis

scientific article published on 01 October 2018

In more languages

default for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30371255%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

Porphyrin-Based SOD Mimic MnTnBu OE -2-PyP5+ Inhibits Mechanisms of Aortic Valve Remodeling in Human and Murine Models of Aortic Valve Sclerosis (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30371255%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

1 reference

based on heuristic

inferred from title

Ines Batinic-Haberle

11

object named as

Ines Batinic-Haberle

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30371255%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

author name string

Wanda Anselmo

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30371255%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

Emanuela Branchetti

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30371255%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

Juan B Grau

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30371255%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

Gen Li

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30371255%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

Salma Ayoub

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30371255%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

Eric K Lai

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30371255%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

Nancy Rioux

7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30371255%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

Artak Tovmasyan

8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30371255%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

Jacqueline H Fortier

9

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30371255%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

Michael S Sacks

10

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30371255%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

Stanley L Hazen

12

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30371255%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

Robert J Levy

13

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30371255%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

Giovanni Ferrari

14

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30371255%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

language of work or name

0 references

publication date

1 October 2018

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30371255%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30371255%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30371255%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

20

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30371255%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

e007861

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30371255%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6474974/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Association of Aortic-Valve Sclerosis with Cardiovascular Mortality and Morbidity in the Elderly

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Favourable and unfavourable effects on long-term survival of radiotherapy for early breast cancer: an overview of the randomised trials]

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Asymptomatic cardiac disease following mediastinal irradiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Valvular dysfunction and carotid, subclavian, and coronary artery disease in survivors of hodgkin lymphoma treated with radiation therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A randomized trial of intensive lipid-lowering therapy in calcific aortic stenosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation between heart valve interstitial cell stiffness and transvalvular pressure: implications for collagen biosynthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Osteopontin and cardiovascular system

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming growth factor-beta1 mechanisms in aortic valve calcification: increased alkaline phosphatase and related events.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differences in tissue-remodeling potential of aortic and pulmonary heart valve interstitial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel aspects of oxidative stress in cardiovascular diseases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Valvular dysfunction and left ventricular changes in Hodgkin's lymphoma survivors. A longitudinal study

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered oxidative stress responses and increased type I collagen expression in bicuspid aortic valve patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Do statins improve outcomes and delay the progression of non-rheumatic calcific aortic stenosis?

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aortic valve sclerosis and clinical outcomes: moving toward a definition

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcific aortic valve disease: new concepts

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of serum phosphate levels with aortic valve sclerosis and annular calcification: the cardiovascular health study

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcific aortic valve disease: not simply a degenerative process: A review and agenda for research from the National Heart and Lung and Blood Institute Aortic Stenosis Working Group. Executive summary: Calcific aortic valve disease-2011 update.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of osteopontin levels for the identification of asymptomatic patients with calcific aortic valve disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new SOD mimic, Mn(III) ortho N-butoxyethylpyridylporphyrin, combines superb potency and lipophilicity with low toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased transcript level of poly(ADP-ribose) polymerase (PARP-1) in human tricuspid compared with bicuspid aortic valves correlates with the stenosis severity

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matricellular proteins in cardiac adaptation and disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Design, mechanism of action, bioavailability and therapeutic effects of mn porphyrin-based redox modulators.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antioxidant enzymes reduce DNA damage and early activation of valvular interstitial cells in aortic valve sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Noggin attenuates the osteogenic activation of human valve interstitial cells in aortic valve sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A nonclinical safety assessment of MnTE-2-PyP, a manganese porphyrin

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of transesophageal echocardiographic analysis and circulating biomarker expression profile in calcific aortic valve disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular and cellular aspects of calcific aortic valve disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SOD therapeutics: latest insights into their structure-activity relationships and impact on the cellular redox-based signaling pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The susceptibility of bioprosthetic heart valve leaflets to oxidation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TGF-beta1-Induced MAPK activation promotes collagen synthesis, nodule formation, redox stress and cellular senescence in porcine aortic valve interstitial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Osteopontin-CD44v6 interaction mediates calcium deposition via phospho-Akt in valve interstitial cells from patients with noncalcified aortic valve sclerosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcific aortic valve disease: a consensus summary from the Alliance of Investigators on Calcific Aortic Valve Disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5-year outcomes of transcatheter aortic valve replacement compared with standard treatment for patients with inoperable aortic stenosis (PARTNER 1): a randomised controlled trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nonbiased Molecular Screening Identifies Novel Molecular Regulators of Fibrogenic and Proliferative Signaling in Myxomatous Mitral Valve Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An educational overview of the chemistry, biochemistry and therapeutic aspects of Mn porphyrins--From superoxide dismutation to H2O2-driven pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nonclinical Safety and Toxicokinetics of MnTnBuOE-2-PyP5+ (BMX-001).

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Challenges encountered during development of Mn porphyrin-based, potent redox-active drug and superoxide dismutase mimic, MnTnBuOE-2-PyP5+, and its alkoxyalkyl analogues

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel redox regulator, MnTnBuOE-2-PyP5+, enhances normal hematopoietic stem/progenitor cell function

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcification and Oxidative Modifications Are Associated With Progressive Bioprosthetic Heart Valve Dysfunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/30371255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1161/JAHA.117.007861

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30371255%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30371255%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30371255%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q58121844&oldid=1984673001"