(Q58199161)

English

Phosphorylation of the LFA-1 Integrin β2-Chain on Thr-758 Leads to Adhesion, Rac-1/Cdc42 Activation, and Stimulation of CD69 Expression in Human T Cells

scientific article published in Journal of Biological Chemistry

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scholarly article

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17107954%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Phosphorylation of the LFA-1 integrin beta2-chain on Thr-758 leads to adhesion, Rac-1/Cdc42 activation, and stimulation of CD69 expression in human T cells (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17107954%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

phosphorylation

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3

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21 December 2019

Carl G. Gahmberg

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21 December 2019

Susanna C Fagerholm

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21 December 2019

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Matti Autero

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21 December 2019

Susanna M Nurmi

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21 December 2019

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15 November 2006

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21 December 2019

Journal of Biological Chemistry

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21 December 2019

282

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21 December 2019

2

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21 December 2019

968-975

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21 December 2019

Adhesion receptors of the immune system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608524200

21 January 2018

Leukocyte adhesion: CD11/CD18 integrins and intercellular adhesion molecules

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608524200

21 January 2018

Rap1 is a potent activation signal for leukocyte function-associated antigen 1 distinct from protein kinase C and phosphatidylinositol-3-OH kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608524200

21 January 2018

Lck tyrosine kinase is important for activation of the CD11a/CD18-integrins in human T lymphocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608524200

21 January 2018

Phosphorylation of the cytoplasmic domain of the integrin CD18 chain by protein kinase C isoforms in leukocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608524200

21 January 2018

The PH domain and the polybasic c domain of cytohesin-1 cooperate specifically in plasma membrane association and cellular function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608524200

21 January 2018

LFA-1-mediated adhesion is regulated by cytoskeletal restraint and by a Ca2+-dependent protease, calpain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608524200

21 January 2018

An essential role for calmodulin in regulating human T cell aggregation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608524200

21 January 2018

Integrin avidity regulation: are changes in affinity and conformation underemphasized?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608524200

21 January 2018

Avidity regulation of integrins: the driving force in leukocyte adhesion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608524200

21 January 2018

Specific integrin alpha and beta chain phosphorylations regulate LFA-1 activation through affinity-dependent and -independent mechanisms

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608524200

21 January 2018

Cytoskeletal regulation couples LFA-1 conformational changes to receptor lateral mobility and clustering

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608524200

21 January 2018

Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608524200

21 January 2018

A talin-dependent LFA-1 focal zone is formed by rapidly migrating T lymphocytes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608524200

21 January 2018

Beta 2-integrin LFA-1 signaling through phospholipase C-gamma 1 activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608524200

21 January 2018

Signaling through the leukocyte integrin LFA-1 in T cells induces a transient activation of Rac-1 that is regulated by Vav and PI3K/Akt-1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608524200

21 January 2018

P marks the spot: site-specific integrin phosphorylation regulates molecular interactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608524200

21 January 2018

Threonine phosphorylation sites in the beta 2 and beta 7 leukocyte integrin polypeptides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608524200

21 January 2018

GTPases and T cell activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608524200

21 January 2018

Immunological mapping of the human leucocyte adhesion glycoprotein gp90 (CD18) by monoclonal antibodies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608524200

21 January 2018

Mouse A6/twinfilin is an actin monomer-binding protein that localizes to the regions of rapid actin dynamics

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608524200

21 January 2018

Integrin signaling to the actin cytoskeleton.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608524200

21 January 2018

Rho and Rho-associated kinase modulate the tyrosine kinase PYK2 in T-cells through regulation of the activity of the integrin LFA-1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608524200

21 January 2018

Leukocyte functional antigen 1 lowers T cell activation thresholds and signaling through cytohesin-1 and Jun-activating binding protein 1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608524200

21 January 2018

The immunological synapse: integrins take the stage.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608524200

21 January 2018

The cytoplasmic domain of the integrin lymphocyte function-associated antigen 1 beta subunit: sites required for binding to intercellular adhesion molecule 1 and the phorbol ester-stimulated phosphorylation site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608524200

21 January 2018

14-3-3 zeta mediates integrin-induced activation of Cdc42 and Rac. Platelet glycoprotein Ib-IX regulates integrin-induced signaling by sequestering 14-3-3 zeta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608524200

21 January 2018

Two distinct cytoplasmic regions of the beta2 integrin chain regulate RhoA function during phagocytosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608524200

21 January 2018

A novel functional interaction between Vav and PKCtheta is required for TCR-induced T cell activation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608524200

21 January 2018

Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608524200

21 January 2018

Identifiers

10.1074/JBC.M608524200

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17107954%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17107954%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

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