(Q42457125)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14960575%20AND%20SRC:MED&resulttype=core&format=json

23 November 2019

title

Signaling through the leukocyte integrin LFA-1 in T cells induces a transient activation of Rac-1 that is regulated by Vav and PI3K/Akt-1 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14960575%20AND%20SRC:MED&resulttype=core&format=json

Miguel Vicente-Manzanares

23 November 2019

author

5

1 reference

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23 November 2019

Antonio Cuadrado

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14960575%20AND%20SRC:MED&resulttype=core&format=json

23 November 2019

Francisco Sánchez-Madrid

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14960575%20AND%20SRC:MED&resulttype=core&format=json

23 November 2019

Ana I Rojo

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14960575%20AND%20SRC:MED&resulttype=core&format=json

23 November 2019

Paloma Sánchez-mateos

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14960575%20AND%20SRC:MED&resulttype=core&format=json

23 November 2019

Xosé R. Bustelo

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14960575%20AND%20SRC:MED&resulttype=core&format=json

José Luis Rodríguez-Fernández

23 November 2019

11

1 reference

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23 November 2019

Carlos Cabanas

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14960575%20AND%20SRC:MED&resulttype=core&format=json

23 November 2019

author name string

Lorena Sánchez-Martín

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14960575%20AND%20SRC:MED&resulttype=core&format=json

23 November 2019

Noelia Sánchez-Sánchez

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14960575%20AND%20SRC:MED&resulttype=core&format=json

23 November 2019

M Dolores Gutiérrez-López

3

1 reference

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23 November 2019

María José Pérez-Alvarez

6

1 reference

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23 November 2019

language of work or name

English

0 references

publication date

11 February 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14960575%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

23 November 2019

published in

1 reference

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23 November 2019

volume

279

1 reference

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23 November 2019

issue

16

1 reference

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23 November 2019

page(s)

16194-16205

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14960575%20AND%20SRC:MED&resulttype=core&format=json

Leukocyte polarization in cell migration and immune interactions

23 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Cytoskeletal rearrangement during migration and activation of T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

The immunological synapse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

21 January 2018

The leukocyte integrins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Leukocyte integrins and inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Chemokines and the arrest of lymphocytes rolling under flow conditions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Divalent cation regulation of the function of the leukocyte integrin LFA-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Antibodies that activate beta 2 integrins can generate different ligand binding states

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Adhesion through the interaction of lymphocyte function-associated antigen-1 with intracellular adhesion molecule-1 induces tyrosine phosphorylation of p130cas and its association with c-CrkII.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Signaling through integrin LFA-1 leads to filamentous actin polymerization and remodeling, resulting in enhanced T cell adhesion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Leukocyte function-associated antigen 1 is an activation molecule for human T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Beta 2-integrin LFA-1 signaling through phospholipase C-gamma 1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Induction of tyrosine phosphorylation during ICAM-3 and LFA-1-mediated intercellular adhesion, and its regulation by the CD45 tyrosine phosphatase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

The interaction of activated integrin lymphocyte function-associated antigen 1 with ligand intercellular adhesion molecule 1 induces activation and redistribution of focal adhesion kinase and proline-rich tyrosine kinase 2 in T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Rho and Rho-associated kinase modulate the tyrosine kinase PYK2 in T-cells through regulation of the activity of the integrin LFA-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

The phosphoinositide 3-kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Signalling through phosphoinositide 3-kinases: the lipids take centre stage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

An intracellular signaling hierarchy determines direction of migration in opposing chemotactic gradients

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Rho GTPases and their effector proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Rho family GTPases: more than simple switches

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Role of the cytoskeleton during leukocyte responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Rac regulates integrin-mediated spreading and increased adhesion of T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Rho GTPases control migration and polarization of adhesion molecules and cytoskeletal ERM components in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Rho proteins, PI 3-kinases, and monocyte/macrophage motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Regulatory and signaling properties of the Vav family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Structural determinants for the biological activity of Vav proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

The binding site on ICAM-1 for Plasmodium falciparum-infected erythrocytes overlaps, but is distinct from, the LFA-1-binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Chemokines regulate cellular polarization and adhesion receptor redistribution during lymphocyte interaction with endothelium and extracellular matrix. Involvement of cAMP signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Tyrosine phosphorylation mediates both activation and downmodulation of the biological activity of Vav

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Rac1 and RhoG promote cell survival by the activation of PI3K and Akt, independently of their ability to stimulate JNK and NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Akt1/PKBalpha protects PC12 cells against the parkinsonism-inducing neurotoxin 1-methyl-4-phenylpyridinium and reduces the levels of oxygen-free radicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Ceramide and reactive oxygen species generated by H2O2 induce caspase-3-independent degradation of Akt/protein kinase B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Guanine exchange-dependent and -independent effects of Vav1 on integrin-induced T cell spreading

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Antibody-induced engagement of beta 2 integrins on adherent human neutrophils triggers activation of p21ras through tyrosine phosphorylation of the protooncogene product Vav

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Structural basis for relief of autoinhibition of the Dbl homology domain of proto-oncogene Vav by tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Akt protein kinase inhibits Rac1-GTP binding through phosphorylation at serine 71 of Rac1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

A motif-based profile scanning approach for genome-wide prediction of signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

The crystal structure of human rac1, a member of the rho-family complexed with a GTP analogue

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Down-regulation of Rac activity during beta 2 integrin-mediated adhesion of human neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Invasion of T-lymphoma cells: cooperation between Rho family GTPases and lysophospholipid receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

A role for Cdc42 in macrophage chemotaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Phosphatidylinositol 4,5-bisphosphate functions as a second messenger that regulates cytoskeleton-plasma membrane adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Filamin is essential in actin cytoskeletal assembly mediated by p21-activated kinase 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Stromal cell-derived factor 1alpha activates LIM kinase 1 and induces cofilin phosphorylation for T-cell chemotaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Cytoskeletal remodeling in lymphocyte activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Formins: signaling effectors for assembly and polarization of actin filaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Functional and physical interactions of Syk family kinases with the Vav proto-oncogene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

Enhancement of LFA-1-mediated cell adhesion by triggering through CD2 or CD3 on T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

KIM127, an antibody that promotes adhesion, maps to a region of CD18 that includes cysteine-rich repeats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400905200

21 January 2018

Identifiers

DOI

10.1074/JBC.M400905200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14960575%20AND%20SRC:MED&resulttype=core&format=json

release_naa7rui6bradbltcrfsypmw36m

23 November 2019

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/naa7rui6bradbltcrfsypmw36m

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference