(Q44126933)

30 November 2017

title

Ceramide and reactive oxygen species generated by H2O2 induce caspase-3-independent degradation of Akt/protein kinase B. (English)

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30 November 2017

main subject

reactive oxygen species

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5

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30 November 2017

Daniel Martin

1

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30 November 2017

Marta Salinas

series ordinal

2

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30 November 2017

Naoya Fujita

series ordinal

3

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30 November 2017

Takashi Tsuruo

series ordinal

4

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30 November 2017

language of work or name

English

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publication date

3 September 2002

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Journal of Biological Chemistry

30 November 2017

number of pages

10

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based on heuristic

inferred from page(s)

published in

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30 November 2017

volume

277

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30 November 2017

issue

45

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30 November 2017

page(s)

42943-42952

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Fundamental aspects of reactive oxygen species, or what's the matter with oxygen?

30 November 2017

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Akt is activated in response to an apoptotic signal.

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The activation of protein kinase B by H2O2 or heat shock is mediated by phosphoinositide 3-kinase and not by mitogen-activated protein kinase-activated protein kinase-2

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Regulation of insulin-stimulated glucose transporter GLUT4 translocation and Akt kinase activity by ceramide.

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Cleavage and inactivation of antiapoptotic Akt/PKB by caspases during apoptosis

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The cleavage of Akt/protein kinase B by death receptor signaling is an important event in detachment-induced apoptosis

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Ceramide generation by two distinct pathways in tumor necrosis factor alpha-induced cell death

21 January 2018

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p53 regulates ceramide formation by neutral sphingomyelinase through reactive oxygen species in human glioma cells

21 January 2018

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Loss in oxidative stress tolerance with aging linked to reduced extracellular signal-regulated kinase and Akt kinase activities

21 January 2018

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Epidermal growth factor receptor-dependent Akt activation by oxidative stress enhances cell survival

21 January 2018

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Quantitative determination of ceramide using diglyceride kinase

21 January 2018

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Glutathione: an overview of biosynthesis and modulation

21 January 2018

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Detection of apoptosis and changes in mitochondrial membrane potential with chloromethyl-X-rosamine

21 January 2018

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Inhibition of the neutral magnesium-dependent sphingomyelinase by glutathione

21 January 2018

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A new four-color flow cytometric assay to detect apoptosis in lymphocyte subsets of cultured peripheral blood cells

21 January 2018

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Analysis of sphingomyelin and ceramide levels and the enzymes regulating their metabolism in response to cell stress

21 January 2018

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Ceramide formation leads to caspase-3 activation during hypoxic PC12 cell death. Inhibitory effects of Bcl-2 on ceramide formation and caspase-3 activation

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M201070200

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30 November 2017

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