(Q58294694)

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Conserved Synteny Between the Ciona Genome and Human Paralogons Identifies Large Duplication Events in the Molecular Evolution of the Insulin-Relaxin Gene Family

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Conserved Synteny Between the Ciona Genome and Human Paralogons Identifies Large Duplication Events in the Molecular Evolution of the Insulin-Relaxin Gene Family (English)

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Finn Hallböök

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Finn Hallböök

3

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author name string

Robert Piotr Olinski

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Lars-Gustav Lundin

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publication date

31 August 2005

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Molecular Biology and Evolution

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23

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1

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10-22

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Evidence of en bloc duplication in vertebrate genomes

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

Recent segmental duplications in the human genome

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

Evolution of the insulin superfamily: cloning of a hybrid insulin/insulin-like growth factor cDNA from amphioxus

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

Fugu genome analysis provides evidence for a whole-genome duplication early during the evolution of ray-finned fishes

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

Evolution of the insulin molecule: insights into structure-activity and phylogenetic relationships

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

The structure of Mordacia mordax insulin supports the monophyly of the Petromyzontiformes and an ancient divergence of Mordaciidae and Geotriidae

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

MetaHox gene clusters

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

The Draft Genome of Ciona intestinalis: Insights into Chordate and Vertebrate Origins

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

Is it possible to construct phylogenetic trees using polypeptide hormone sequences?

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

New insulin-like proteins with atypical disulfide bond pattern characterized in Caenorhabditis elegans by comparative sequence analysis and homology modeling.

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

Recent duplication, domain accretion and the dynamic mutation of the human genome

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

An efficient algorithm for large-scale detection of protein families

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

Towards the delineation of the ancestral eutherian genome organization: comparative genome maps of human and the African elephant (Loxodonta africana) generated by chromosome painting

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

Age distribution of human gene families shows significant roles of both large- and small-scale duplications in vertebrate evolution

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

Evolution of the vertebrate neurotrophin and Trk receptor gene families

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

New insights into the evolution of the relaxin-LGR signaling system

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

The three subfamilies of leucine-rich repeat-containing G protein-coupled receptors (LGR): identification of LGR6 and LGR7 and the signaling mechanism for LGR7

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

Activation of orphan receptors by the hormone relaxin

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

A second insulin gene in fish genomes.

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

Genome duplication in the teleost fish Tetraodon nigroviridis reveals the early vertebrate proto-karyotype

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

Paralogy mapping: identification of a region in the human MHC triplicated onto human chromosomes 1 and 9 allows the prediction and isolation of novel PBX and NOTCH loci

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

INSL3/Leydig insulin-like peptide activates the LGR8 receptor important in testis descent

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

cDNAs from neurosecretory cells of brains of Locusta migratoria (Insecta, Orthoptera) encoding a novel member of the superfamily of insulins

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

Identification of Relaxin-3/INSL7 as a Ligand for GPCR142

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

INSL5 is a high affinity specific agonist for GPCR142 (GPR100)

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

Evolution of the vertebrate genome as reflected in paralogous chromosomal regions in man and the house mouse

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

Numerous groups of chromosomal regional paralogies strongly indicate two genome doublings at the root of the vertebrates

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

Extensive genomic duplication during early chordate evolution

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

Ancient divergence of insulin and insulin-like growth factor

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

The origin of human chromosome 1 and its homologs in placental mammals

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

Three-dimensional solution structure of bombyxin-II an insulin-like peptide of the silkmoth Bombyx mori: structural comparison with insulin and relaxin

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

Complex history of a chromosomal paralogy region: insights from amphioxus aromatic amino acid hydroxylase genes and insulin-related genes

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

Homeobox gene clusters and the human paralogy map.

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

Coparalogy: physical and functional clusterings in the human genome.

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

A genomewide survey of developmentally relevant genes in Ciona intestinalis. V. Genes for receptor tyrosine kinase pathway and Notch signaling pathway

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

Ciona intestinalis cDNA projects: expressed sequence tag analyses and gene expression profiles during embryogenesis.

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

Towards understanding the role of insulin in the brain: lessons from insulin-related signaling systems in the invertebrate brain.

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

Growth-controlling molluscan neurons produce the precursor of an insulin-related peptide

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

Comparative mapping of human Chromosome 19 with the chicken shows conserved synteny and gives an insight into chromosomal evolution

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

H3 relaxin is a specific ligand for LGR7 and activates the receptor by interacting with both the ectodomain and the exoloop 2

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

Computational approaches to unveiling ancient genome duplications

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

Major events in the genome evolution of vertebrates: paranome age and size differ considerably between ray-finned fishes and land vertebrates

1 reference

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21 January 2018

Evidence that rice and other cereals are ancient aneuploids

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21 January 2018

Systematic phylogenomic evidence of en bloc duplication of the ancestral 8p11.21-8p21.3-like region

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

The origins of genomic duplications in Arabidopsis.

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

Refolding of amphioxus insulin-like peptide: implications of a bifurcating evolution of the different folding behavior of insulin and insulin-like growth factor 1.

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

Evolution of the relaxin-like peptide family

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

Molecular evidence for an ancient duplication of the entire yeast genome

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

Reciprocal chromosome painting among human, aardvark, and elephant (superorder Afrotheria) reveals the likely eutherian ancestral karyotype

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

Structure and the evolutionary implication of the triplicated complement factor B genes of a urochordate ascidian, Ciona intestinalis

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ002

21 January 2018

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10.1093/MOLBEV/MSJ002

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