(Q58449597)

English

Characterization of a Bicyclic Peptide Neuropilin-1 (NP-1) Antagonist (EG3287) Reveals Importance of Vascular Endothelial Growth Factor Exon 8 for NP-1 Binding and Role of NP-1 in KDR Signaling

scientific article published in Journal of Biological Chemistry

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16513643%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Characterization of a bicyclic peptide neuropilin-1 (NP-1) antagonist (EG3287) reveals importance of vascular endothelial growth factor exon 8 for NP-1 binding and role of NP-1 in KDR signaling (English)

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17 January 2020

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Paul C. Driscoll

12

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17 January 2020

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Haiyan Jia

1

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17 January 2020

Azadeh Bagherzadeh

2

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17 January 2020

Basil Hartzoulakis

3

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17 January 2020

Ashley Jarvis

4

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17 January 2020

Marianne Löhr

5

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17 January 2020

Shaheda Shaikh

6

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17 January 2020

Rehan Aqil

7

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17 January 2020

Lili Cheng

8

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17 January 2020

Michelle Tickner

9

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17 January 2020

Diego Esposito

10

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17 January 2020

Richard Harris

11

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17 January 2020

David L Selwood

13

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17 January 2020

Ian C Zachary

14

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17 January 2020

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publication date

2 March 2006

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17 January 2020

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10

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Journal of Biological Chemistry

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17 January 2020

281

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17 January 2020

19

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17 January 2020

13493-13502

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17 January 2020

Angiogenesis in cancer and other diseases

1 reference

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21 January 2018

The vascular endothelial growth factor family: identification of a fourth molecular species and characterization of alternative splicing of RNA.

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21 January 2018

VEGF signalling: integration and multi-tasking in endothelial cell biology

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Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4)

1 reference

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A novel type of vascular endothelial growth factor, VEGF-E (NZ-7 VEGF), preferentially utilizes KDR/Flk-1 receptor and carries a potent mitotic activity without heparin-binding domain

1 reference

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21 January 2018

Vascular endothelial growth factor (VEGF)-like protein from orf virus NZ2 binds to VEGFR2 and neuropilin-1

1 reference

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21 January 2018

A novel vascular endothelial growth factor encoded by Orf virus, VEGF-E, mediates angiogenesis via signalling through VEGFR-2 (KDR) but not VEGFR-1 (Flt-1) receptor tyrosine kinases

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21 January 2018

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Signaling transduction mechanisms mediating biological actions of the vascular endothelial growth factor family

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21 January 2018

Vascular endothelial growth factor stimulates prostacyclin production and activation of cytosolic phospholipase A2 in endothelial cells via p42/p44 mitogen-activated protein kinase

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21 January 2018

Vascular endothelial growth factor (VEGF)-D and VEGF-A differentially regulate KDR-mediated signaling and biological function in vascular endothelial cells

1 reference

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21 January 2018

Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation

1 reference

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21 January 2018

A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells

1 reference

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21 January 2018

Vascular endothelial growth factor stimulates tyrosine phosphorylation and recruitment to new focal adhesions of focal adhesion kinase and paxillin in endothelial cells

1 reference

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21 January 2018

Vascular permeability factor (VPF)/vascular endothelial growth factor (VEGF) peceptor-1 down-modulates VPF/VEGF receptor-2-mediated endothelial cell proliferation, but not migration, through phosphatidylinositol 3-kinase-dependent pathways

1 reference

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21 January 2018

Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512121200

21 January 2018

Differential binding of vascular endothelial growth factor B splice and proteolytic isoforms to neuropilin-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512121200

21 January 2018

Neuropilin is a receptor for the axonal chemorepellent Semaphorin III

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512121200

21 January 2018

Neuropilin is a semaphorin III receptor

1 reference

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21 January 2018

Roles of a neuronal cell-surface molecule, neuropilin, in nerve fiber fasciculation and guidance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512121200

21 January 2018

Neuropilin-2, a novel member of the neuropilin family, is a high affinity receptor for the semaphorins Sema E and Sema IV but not Sema III

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512121200

21 January 2018

Semaphorin-neuropilin interactions underlying sympathetic axon responses to class III semaphorins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512121200

21 January 2018

Neuropilin-2 is a receptor for semaphorin IV: insight into the structural basis of receptor function and specificity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512121200

21 January 2018

Semaphorins A and E act as antagonists of neuropilin-1 and agonists of neuropilin-2 receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512121200

21 January 2018

Targeting of both mouse neuropilin-1 and neuropilin-2 genes severely impairs developmental yolk sac and embryonic angiogenesis

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21 January 2018

Characterization of novel vascular endothelial growth factor (VEGF) receptors on tumor cells that bind VEGF165 via its exon 7-encoded domain

1 reference

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21 January 2018

Anti-chemorepulsive effects of vascular endothelial growth factor and placental growth factor-2 in dorsal root ganglion neurons are mediated via neuropilin-1 and cyclooxygenase-derived prostanoid production

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21 January 2018

Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions

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Influence of non-bonded parameters on the quality of NMR structures: a new force field for NMR structure calculation

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Solution structure of the heparin-binding domain of vascular endothelial growth factor

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Disulfide bond formation in peptides by dimethyl sulfoxide. Scope and applications

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Identifiers

10.1074/JBC.M512121200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16513643%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16513643%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

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