(Q58477330)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21382117%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

title

Neprilysin protects against cerebral amyloid angiopathy and Aβ-induced degeneration of cerebrovascular smooth muscle cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21382117%20AND%20SRC:MED&resulttype=core&format=json

cerebral amyloid angiopathy

24 January 2020

main subject

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21382117%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

author name string

James Scott Miners

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21382117%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

Seth Love

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21382117%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

publication date

3 April 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21382117%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21382117%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

volume

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21382117%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21382117%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

page(s)

594-605

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21382117%20AND%20SRC:MED&resulttype=core&format=json

Progression of cerebral amyloid angiopathy: accumulation of amyloid-beta40 in affected vessels.

24 January 2020

cites work

1 reference

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Alzheimer's disease pathology influences severity and topographical distribution of cerebral amyloid angiopathy.

21 January 2018

1 reference

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Neuropathological stageing of Alzheimer-related changes

21 January 2018

1 reference

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Mechanisms of cerebrovascular amyloid deposition. Lessons from mouse models

21 January 2018

1 reference

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Solutes, but not cells, drain from the brain parenchyma along basement membranes of capillaries and arteries: significance for cerebral amyloid angiopathy and neuroimmunology

21 January 2018

1 reference

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Declining expression of neprilysin in Alzheimer disease vasculature: possible involvement in cerebral amyloid angiopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

APOE epsilon 4 influences the pathological phenotype of Alzheimer's disease by favouring cerebrovascular over parenchymal accumulation of A beta protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

Enhanced pathologic properties of Dutch-type mutant amyloid beta-protein

21 January 2018

1 reference

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Regulation of steady-state beta-amyloid levels in the brain by neprilysin and endothelin-converting enzyme but not angiotensin-converting enzyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

Neprilysin protects neurons against Abeta peptide toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

Vascular smooth muscle actin is reduced in Alzheimer disease brain: a quantitative analysis.

21 January 2018

1 reference

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Loss of neprilysin function promotes amyloid plaque formation and causes cerebral amyloid angiopathy

21 January 2018

1 reference

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The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part X. Neuropathology confirmation of the clinical diagnosis of Alzheimer's disease

21 January 2018

1 reference

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Reducing amyloid plaque burden via ex vivo gene delivery of an Abeta-degrading protease: a novel therapeutic approach to Alzheimer disease.

21 January 2018

1 reference

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Cerebrovascular smooth muscle actin is increased in nondemented subjects with frequent senile plaques at autopsy: implications for the pathogenesis of Alzheimer disease.

21 January 2018

1 reference

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New neuropathological criteria for Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

Metabolic regulation of brain Abeta by neprilysin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

Presynaptic localization of neprilysin contributes to efficient clearance of amyloid-beta peptide in mouse brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

The C-terminus of the beta protein is critical in amyloidogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

Human neprilysin is capable of degrading amyloid beta peptide not only in the monomeric form but also the pathological oligomeric form

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

Degeneration of vascular muscle cells in cerebral amyloid angiopathy of Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

Population studies of sporadic cerebral amyloid angiopathy and dementia: a systematic review.

21 January 2018

1 reference

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Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

APOE and cerebral amyloid angiopathy in the elderly

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

Insights into the pathogenesis and pathogenicity of cerebral amyloid angiopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

Decreased expression and activity of neprilysin in Alzheimer disease are associated with cerebral amyloid angiopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

Immunocapture-based fluorometric assay for the measurement of neprilysin-specific enzyme activity in brain tissue homogenates and cerebrospinal fluid

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

Neprilysin and insulin-degrading enzyme levels are increased in Alzheimer disease in relation to disease severity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

Changes with age in the activities of beta-secretase and the Abeta-degrading enzymes neprilysin, insulin-degrading enzyme and angiotensin-converting enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

The apolipoprotein E epsilon 4 allele is associated with increased neuritic plaques and cerebral amyloid angiopathy in Alzheimer's disease and Lewy body variant

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

Cerebral amyloid angiopathies: a pathologic, biochemical, and genetic view

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

Somatostatin regulates brain amyloid beta peptide Abeta42 through modulation of proteolytic degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

High-definition characterization of cerebral β-amyloid angiopathy in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

Cerebral cortical arteriolar angiopathy, vascular beta-amyloid, smooth muscle actin, Braak stage, and APOE genotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

Capillary cerebral amyloid angiopathy identifies a distinct APOE epsilon4-associated subtype of sporadic Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

Relationships in Alzheimer's disease between the extent of Abeta deposition in cerebral blood vessel walls, as cerebral amyloid angiopathy, and the amount of cerebrovascular smooth muscle cells and collagen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

The distribution of cerebrovascular amyloid in Alzheimer's disease varies with ApoE genotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

A micromethod for the isolation of large and small microvessels from frozen autopsied human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

Prominent cerebral amyloid angiopathy in transgenic mice overexpressing the london mutant of human APP in neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

Characterisation of two antibodies to oligomeric Abeta and their use in ELISAs on human brain tissue homogenates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

Higher soluble amyloid beta concentration in frontal cortex of young adults than in normal elderly or Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

Oligomeric Abeta in Alzheimer's disease: relationship to plaque and tangle pathology, APOE genotype and cerebral amyloid angiopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

Amyloid beta-protein induces the cerebrovascular cellular pathology of Alzheimer's disease and related disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

Cholesterol homeostasis in neurons and glial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

Cerebral amyloid angiopathy: incidence and complications in the aging brain. II. The distribution of amyloid vascular changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

Microvasculature in brain biopsy specimens from patients with Alzheimer's disease: an immunohistochemical and ultrastructural study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

Toxicity of Dutch (E22Q) and Flemish (A21G) mutant amyloid beta proteins to human cerebral microvessel and aortic smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

Cerebral amyloid angiopathy: both viper and maggot in the brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

Perivascular drainage of amyloid-beta peptides from the brain and its failure in cerebral amyloid angiopathy and Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

Beta-amyloid formation by myocytes of leptomeningeal vessels

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

Cerebral amyloid angiopathy: progressive disruption of the neurovascular unit

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2011.00486.X

10.1111/J.1750-3639.2011.00486.X

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21382117%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

1 reference