(Q58813365)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16751810%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

title

Functional analyses and molecular modeling of two c-Kit mutations responsible for imatinib secondary resistance in GIST patients (English)

1 reference

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29 January 2020

1 reference

1

1 reference

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29 January 2020

Sabrina Pricl

2

1 reference

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29 January 2020

Tiziana Negri

3

1 reference

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29 January 2020

Angela Greco

6

1 reference

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29 January 2020

Alessandro Gronchi

7

1 reference

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29 January 2020

Paolo Giovanni Casali

8

1 reference

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29 January 2020

Maurizio Fermeglia

10

1 reference

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29 January 2020

Antonino Carbone

11

1 reference

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29 January 2020

Marco A. Pierotti

12

1 reference

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29 January 2020

author name string

M S Lagonigro

4

1 reference

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29 January 2020

F Miselli

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16751810%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

M Ferrone

9

1 reference

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29 January 2020

S Pilotti

13

1 reference

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29 January 2020

language of work or name

English

0 references

publication date

5 June 2006

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29 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16751810%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

volume

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16751810%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

page(s)

6140-6146

1 reference

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29 January 2020

issue

45

1 reference

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1209639

29 January 2020

exact match

0 references

cites work

Acquired resistance to imatinib in gastrointestinal stromal tumor occurs through secondary gene mutation

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7 January 2021

Molecular dynamics with coupling to an external bath

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7 January 2021

Structural and energetic responses to cavity-creating mutations in hydrophobic cores: observation of a buried water molecule and the hydrophilic nature of such hydrophobic cavities

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7 January 2021

A missense mutation in KIT kinase domain 1 correlates with imatinib resistance in gastrointestinal stromal tumors

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7 January 2021

Biology of gastrointestinal stromal tumors.

1 reference

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7 January 2021

KIT mutations are common in incidental gastrointestinal stromal tumors one centimeter or less in size

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7 January 2021

A Second Generation Force Field for the Simulation of Proteins, Nucleic Acids, and Organic Molecules

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7 January 2021

Mechanisms of resistance to imatinib mesylate in gastrointestinal stromal tumors and activity of the PKC412 inhibitor against imatinib-resistant mutants

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7 January 2021

The development of imatinib as a therapeutic agent for chronic myeloid leukemia

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7 January 2021

High apparent dielectric constants in the interior of a protein reflect water penetration

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7 January 2021

Response of a protein structure to cavity-creating mutations and its relation to the hydrophobic effect

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7 January 2021

Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor

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7 January 2021

Comparison of simple potential functions for simulating liquid water

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7 January 2021

Contribution of hydrophobic interactions to protein stability

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7 January 2021

Estimation of the maximum change in stability of globular proteins upon mutation of a hydrophobic residue to another of smaller size

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7 January 2021

Thermodynamic consequences of burial of polar and non-polar amino acid residues in the protein interior

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7 January 2021

Structural and genetic analysis of protein stability

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7 January 2021

Structural basis for the autoinhibition and STI-571 inhibition of c-Kit tyrosine kinase

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7 January 2021

Structure of a c-kit product complex reveals the basis for kinase transactivation

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7 January 2021

Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

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7 January 2021

In vitro activity of Bcr-Abl inhibitors AMN107 and BMS-354825 against clinically relevant imatinib-resistant Abl kinase domain mutants

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7 January 2021

Forces contributing to the conformational stability of proteins

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7 January 2021

T315I-mutated Bcr-Abl in chronic myeloid leukemia and imatinib: insights from a computational study

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7 January 2021

Investigating the binding specificity of U1A-RNA by computational mutagenesis

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7 January 2021

Numerical integration of the cartesian equations of motion of a system with constraints: molecular dynamics of n-alkanes

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7 January 2021

Reduced surface: an efficient way to compute molecular surfaces

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7 January 2021

Contribution of polar groups in the interior of a protein to the conformational stability

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7 January 2021

A new mutation in the KIT ATP pocket causes acquired resistance to imatinib in a gastrointestinal stromal tumor patient

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7 January 2021

Acquired resistance to imatinib in gastrointestinal stromal tumours caused by multiple KIT mutations

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7 January 2021