(Q58842537)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15356208%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

title

Genetically decreased spinal cord copper concentration prolongs life in a transgenic mouse model of amyotrophic lateral sclerosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15356208%20AND%20SRC:MED&resulttype=core&format=json

amyotrophic lateral sclerosis

1 January 2020

main subject

0 references

0 references

2

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1 January 2020

Irene Volitakis

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15356208%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

7

M Flint Beal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15356208%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

author name string

Mahmoud Kiaei

1

1 reference

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1 January 2020

Brett M Morrison

3

1 reference

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1 January 2020

John H Morrison

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15356208%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Robert A Cherny

5

1 reference

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1 January 2020

Jon W Gordon

8

1 reference

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1 January 2020

language of work or name

English

0 references

publication date

1 September 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15356208%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

published in

Journal of Neuroscience

1 reference

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1 January 2020

volume

24

1 reference

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1 January 2020

issue

36

1 reference

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1 January 2020

page(s)

7945-7950

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Benefit of a combined treatment with trientine and ascorbate in familial amyotrophic lateral sclerosis model mice

1 January 2020

cites work

1 reference

12 December 2020

Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase

1 reference

12 December 2020

Loss of in vitro metal ion binding specificity in mutant copper-zinc superoxide dismutases associated with familial amyotrophic lateral sclerosis

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12 December 2020

Increased reactive oxygen species in familial amyotrophic lateral sclerosis with mutations in SOD1.

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12 December 2020

Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice.

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12 December 2020

Decreased metallation and activity in subsets of mutant superoxide dismutases associated with familial amyotrophic lateral sclerosis.

1 reference

12 December 2020

Mutant Cu, Zn superoxide dismutase that causes motoneuron degeneration is present in mitochondria in the CNS

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12 December 2020

Mutant SOD1 causes motor neuron disease independent of copper chaperone-mediated copper loading

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12 December 2020

Mutated human SOD1 causes dysfunction of oxidative phosphorylation in mitochondria of transgenic mice.

1 reference

12 December 2020

Is ALS caused by an altered oxidative activity of mutant superoxide dismutase?

1 reference

12 December 2020

Oxidation-induced misfolding and aggregation of superoxide dismutase and its implications for amyotrophic lateral sclerosis

1 reference

12 December 2020

CCS knockout mice establish an alternative source of copper for SOD in ALS

1 reference

12 December 2020

Misfolded CuZnSOD and amyotrophic lateral sclerosis

1 reference

12 December 2020

Mechanisms for activating Cu- and Zn-containing superoxide dismutase in the absence of the CCS Cu chaperone

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12 December 2020

Bacteriocuprein superoxide dismutases in pseudomonads

1 reference

12 December 2020

Primary defect in copper transport underlies mottled mutants in the mouse

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12 December 2020

Superoxide dismutase: improved assays and an assay applicable to acrylamide gels

1 reference

12 December 2020

Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis

1 reference

12 December 2020

Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity

1 reference

12 December 2020

ALS, SOD and peroxynitrite

1 reference

12 December 2020

Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis

1 reference

12 December 2020

A gain-of-function of an amyotrophic lateral sclerosis-associated Cu,Zn-superoxide dismutase mutant: An enhancement of free radical formation due to a decrease in Km for hydrogen peroxide

1 reference

12 December 2020

Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury

1 reference

12 December 2020

A familial amyotrophic lateral sclerosis-associated A4V Cu, Zn-superoxide dismutase mutant has a lower Km for hydrogen peroxide. Correlation between clinical severity and the Km value.

1 reference

12 December 2020

Bcl-2: prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis

1 reference

12 December 2020

The copper chelator d-penicillamine delays onset of disease and extends survival in a transgenic mouse model of familial amyotrophic lateral sclerosis

1 reference

12 December 2020

Stability of mutant superoxide dismutase-1 associated with familial amyotrophic lateral sclerosis determines the manner of copper release and induction of thioredoxin in erythrocytes

1 reference

12 December 2020

Time course of neuropathology in the spinal cord of G86R superoxide dismutase transgenic mice

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12 December 2020

Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1

1 reference

12 December 2020

Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

1 reference

12 December 2020

10.1523/JNEUROSCI.2000-04.2004

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15356208%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15356208%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

PubMed publication ID

15356208

1 reference