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Modeling of Cdc25B Dual Specifity Protein Phosphatase Inhibitors: Docking of Ligands and Enzymatic Inhibition Mechanism
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stated in
Europe PubMed Central
PubMed publication ID
16892390
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16892390%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 December 2019
title
Modeling of Cdc25B dual specifity protein phosphatase inhibitors: docking of ligands and enzymatic inhibition mechanism
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
16892390
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16892390%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 December 2019
main subject
molecular medicine
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author
Antonio Lavecchia
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
16892390
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16892390%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 December 2019
Sandro Cosconati
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2
1 reference
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Europe PubMed Central
PubMed publication ID
16892390
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16892390%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 December 2019
Vittorio Limongelli
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3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
16892390
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16892390%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 December 2019
Ettore Novellino
series ordinal
4
1 reference
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Europe PubMed Central
PubMed publication ID
16892390
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16892390%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 December 2019
publication date
1 May 2006
1 reference
stated in
Europe PubMed Central
PubMed publication ID
16892390
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16892390%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 December 2019
published in
ChemMedChem
1 reference
stated in
Europe PubMed Central
PubMed publication ID
16892390
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16892390%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 December 2019
volume
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
16892390
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16892390%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 December 2019
issue
5
1 reference
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Europe PubMed Central
PubMed publication ID
16892390
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16892390%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 December 2019
page(s)
540-550
1 reference
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Europe PubMed Central
PubMed publication ID
16892390
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16892390%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 December 2019
cites work
Cell cycle regulation by the Cdc25 phosphatase family
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
21 January 2018
Overexpression of cyclin-dependent kinase-activating CDC25B phosphatase in human gastric carcinomas.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
21 January 2018
Protein tyrosine phosphatases: a diverse family of intracellular and transmembrane enzymes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The coordinated action of protein tyrosine phosphatases and kinases in cell signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Form and function in protein dephosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The X-ray crystal structures of Yersinia tyrosine phosphatase with bound tungstate and nitrate. Mechanistic implications
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular mechanisms of the protein serine/threonine phosphatases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The structure and mechanism of protein phosphatases: insights into catalysis and regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein-tyrosine phosphatases: biological function, structural characteristics, and mechanism of catalysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CDC25 phosphatases as potential human oncogenes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cdc25 cell-cycle phosphatase as a target of c-myc
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of the Cdc25A phosphatase in human breast cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human Cdc25 A inactivation in response to S phase inhibition and its role in preventing premature mitosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rapid destruction of human Cdc25A in response to DNA damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Elevated expression of the cdc25A protein phosphatase in colon cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Raf1 interaction with Cdc25 phosphatase ties mitogenic signal transduction to cell cycle activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cdc25 as a potential target of anticancer agents.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of the catalytic domain of the human cell cycle control phosphatase, Cdc25A
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of the catalytic subunit of Cdc25B required for G2/M phase transition of the cell cycle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of the dual specificity protein phosphatase VHR
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of Yersinia protein tyrosine phosphatase at 2.5 A and the complex with tungstate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Automated docking of flexible ligands: applications of AutoDock
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular recognition of receptor sites using a genetic algorithm with a description of desolvation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Development and validation of a genetic algorithm for flexible docking
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparative evaluation of 11 scoring functions for molecular docking
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a potent and selective pharmacophore for Cdc25 dual specificity phosphatase inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of Cdc25 phosphatases by indolyldihydroxyquinones
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sulfonylated aminothiazoles as new small molecule inhibitors of protein phosphatases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synthesis and antitumor activity of some new substituted quinolin-4-one and 1,7-naphthyridin-4-one analogs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel synthetic inhibitor of CDC25 phosphatases: BN82002.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Discovery of a novel protein tyrosine phosphatase-1B inhibitor, KR61639: potential development as an antihyperglycemic agent
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Redox cycling and sulphydryl arylation; their relative importance in the mechanism of quinone cytotoxicity to isolated hepatocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural mechanism of oxidative regulation of the phosphatase Cdc25B via an intramolecular disulfide bond
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Catalytic and chemical competence of regulation of cdc25 phosphatase by oxidation/reduction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Discovery of a potent, highly selective, and orally efficacious small-molecule activator of the insulin receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Strategic approaches to drug design. I. An integrated software framework for molecular modelling.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Iterative partial equalization of orbital electronegativity—a rapid access to atomic charges
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.200500092
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1002/CMDC.200500092
1 reference
stated in
Europe PubMed Central
PubMed publication ID
16892390
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16892390%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 December 2019
PubMed publication ID
16892390
1 reference
stated in
Europe PubMed Central
PubMed publication ID
16892390
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16892390%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 December 2019
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