(Q59005713)

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2 January 2020

title

LNA (locked nucleic acid) and analogs as triplex-forming oligonucleotides (English)

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2 January 2020

1

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2 January 2020

Poul Nielsen

7

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2 January 2020

Jesper Wengel

8

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2 January 2020

author name string

Surender Kumar

2

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2 January 2020

Tadashi Umemoto

4

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2 January 2020

B Ravindra Babu

3

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2 January 2020

Nanna Albaek

5

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2 January 2020

Pawan K Sharma

6

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2 January 2020

publication date

22 June 2007

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Organic and Biomolecular Chemistry

2 January 2020

published in

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2 January 2020

volume

5

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2 January 2020

issue

15

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2 January 2020

page(s)

2375-2379

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Recent improvements in antigene technology

2 January 2020

cites work

1 reference

Triplex formation at physiological pH by oligonucleotides incorporating 5-Me-dC-(N4-spermine).

21 January 2018

1 reference

Triplex formation at physiological pH by 5-Me-dC-N4-(spermine) [X] oligodeoxynucleotides: non protonation of N3 in X of X*G:C triad and effect of base mismatch/ionic strength on triplex stabilities

21 January 2018

1 reference

Nucleosides and nucleotides. Part 214: thermal stability of triplexes containing 4'alpha-C-aminoalkyl-2'-deoxynucleosides

21 January 2018

1 reference

Synthesis and triplex forming properties of pyrrolidino pseudoisocytidine containing oligodeoxynucleotides

21 January 2018

1 reference

Stable DNA triple helix formation using oligonucleotides containing 2'-aminoethoxy,5-propargylamino-U.

21 January 2018

1 reference

Determination of aliphatic side-chain conformation using cross-correlated relaxation: application to an extraordinarily stable 2'-aminoethoxy-modified oligonucleotide triplex

21 January 2018

1 reference

Triplex formation with 2'-O,4'-C-ethylene-bridged nucleic acids (ENA) having C3'-endo conformation at physiological pH.

21 January 2018

1 reference

2'-O,4'-C-ethylene-bridged nucleic acids (ENA): highly nuclease-resistant and thermodynamically stable oligonucleotides for antisense drug

21 January 2018

1 reference

LNA (Locked Nucleic Acids): Synthesis of the adenine, cytosine, guanine, 5-methylcytosine, thymine and uracil bicyclonucleoside monomers, oligomerisation, and unprecedented nucleic acid recognition

21 January 2018

1 reference

LNA: a versatile tool for therapeutics and genomics

21 January 2018

1 reference

2'-O,4'-C-Methylene bridged nucleic acid (2',4'-BNA): synthesis and triplex-forming properties

21 January 2018

1 reference

2'-O,4'-C-methylene bridged nucleic acid modification promotes pyrimidine motif triplex DNA formation at physiological pH: thermodynamic and kinetic studies.

21 January 2018

1 reference

Sequence and pH effects of LNA-containing triple helix-forming oligonucleotides: physical chemistry, biochemistry, and modeling studies

21 January 2018

1 reference

Solution structure of a dsDNA:LNA triplex.

21 January 2018

1 reference

Synthesis of 2‘-Amino-LNA: A Novel Conformationally Restricted High-Affinity Oligonucleotide Analogue with a Handle

21 January 2018

1 reference

Synthesis of 2'-amino-LNA: a new strategy.

21 January 2018

1 reference

Conformationally constrained 2'-N,4'-C-ethylene-bridged thymidine (aza-ENA-T): synthesis, structure, physical, and biochemical studies of aza-ENA-T-modified oligonucleotides.

21 January 2018

1 reference

Multilabeled pyrene-functionalized 2'-amino-LNA probes for nucleic acid detection in homogeneous fluorescence assays

21 January 2018

1 reference

Stable and selective formation of hoogsteen-type triplexes and duplexes using twisted intercalating nucleic acids (TINA) prepared via postsynthetic Sonogashira solid-phase coupling reactions

21 January 2018

1 reference

A Novel Class of Oligonucleotide Analogues Containing 2‘-O,3‘-C-Linked [3.2.0]Bicycloarabinonucleoside Monomers: Synthesis, Thermal Affinity Studies, and Molecular Modeling

21 January 2018

1 reference

NMR solution structure of dsDNA containing a bicyclic D-arabino-configured nucleotide fixed in an O4'-endo sugar conformation

21 January 2018

1 reference

Synthesis of oligodeoxynucleotides containing 4′-C-(Hydroxymethyl)thymidine: Novel promising antisense molecules

21 January 2018

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Novel linear and branched oligodeoxynucleotide analogues containing 4′-c-(hydroxymethyl)thymidine

21 January 2018

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Targeted inhibition of transcription elongation in cells mediated by triplex-forming oligonucleotides

21 January 2018

1 reference

Optimized DNA targeting using N,N-bis(2-pyridylmethyl)-beta-alanyl 2'-amino-LNA.

21 January 2018

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Effect of 5-methylcytosine on the stability of triple-stranded DNA--a thermodynamic study

21 January 2018

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Influence of pH on the equilibrium association constants for oligodeoxyribonucleotide-directed triple helix formation at single DNA sites

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1039/B706101C

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2 January 2020

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