(Q59042062)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21484771%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

title

Hypoxia induces mitochondrial mutagenesis and dysfunction in inflammatory arthritis (English)

1 reference

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28 January 2020

0 references

1 reference

1 reference

2

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28 January 2020

Chin T Ng

4

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28 January 2020

Douglas J Veale

5

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28 January 2020

Ursula Fearon

6

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28 January 2020

Jacintha O'Sullivan

7

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28 January 2020

1

Monika Biniecka

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28 January 2020

author name string

Wei Gao

3

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28 January 2020

publication date

1 August 2011

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28 January 2020

published in

Arthritis and Rheumatism

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28 January 2020

volume

63

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28 January 2020

issue

8

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28 January 2020

page(s)

2172-2182

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Mitochondrial regulation of oxygen sensing

28 January 2020

cites work

1 reference

Energetics, epigenetics, mitochondrial genetics

21 January 2018

1 reference

Mitochondrial DNA mutations in human disease

21 January 2018

1 reference

Oxidative DNA damage causes mitochondrial genomic instability in Saccharomyces cerevisiae

21 January 2018

1 reference

Mitochondria, oxidative stress and cell death

21 January 2018

1 reference

4-Hydroxynonenal-protein adducts: A reliable biomarker of lipid oxidation in liver diseases.

21 January 2018

1 reference

Identification of bovine heart cytochrome c oxidase subunits modified by the lipid peroxidation product 4-hydroxy-2-nonenal

21 January 2018

1 reference

Importance of the bioenergetic reserve capacity in response to cardiomyocyte stress induced by 4-hydroxynonenal

21 January 2018

1 reference

4-Hydroxy-2-nonenal induces calcium overload via the generation of reactive oxygen species in isolated rat cardiac myocytes

21 January 2018

1 reference

Long-chain adducts of trans-4-hydroxy-2-nonenal to DNA bases cause recombination, base substitutions and frameshift mutations in M13 phage

21 January 2018

1 reference

Evolving concepts of rheumatoid arthritis

21 January 2018

1 reference

Molecular and cellular basis of rheumatoid joint destruction

21 January 2018

1 reference

Rheumatoid arthritis and p53: how oxidative stress might alter the course of inflammatory diseases.

21 January 2018

1 reference

Angiogenesis and blood vessel stability in inflammatory arthritis

21 January 2018

1 reference

Synovial tissue hypoxia and inflammation in vivo

21 January 2018

1 reference

Oxidative damage in synovial tissue is associated with in vivo hypoxic status in the arthritic joint.

21 January 2018

1 reference

Defects in multiple complexes of the respiratory chain are present in ageing human colonic crypts

21 January 2018

1 reference

Somatic mutations in the mitochondria of rheumatoid arthritis synoviocytes

21 January 2018

1 reference

The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

21 January 2018

1 reference

Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis

21 January 2018

1 reference

Quantification of random mutations in the mitochondrial genome

21 January 2018

1 reference

Quantitative microscopic analysis of inflammation in rheumatoid arthritis synovial membrane samples selected at arthroscopy compared with samples obtained blindly by needle biopsy

21 January 2018

1 reference

Characterization of SV40T antigen immortalized human synovial fibroblasts: maintained expression patterns of EGR-1, HLA-DR and some surface receptors

21 January 2018

1 reference

Hypoxia activates NF-kappaB-dependent gene expression through the canonical signaling pathway

21 January 2018

1 reference

Hypoxia prolongs monocyte/macrophage survival and enhanced glycolysis is associated with their maturation under aerobic conditions.

21 January 2018

1 reference

Mitochondrial point mutations do not limit the natural lifespan of mice.

21 January 2018

1 reference

Oxidative stress induces degradation of mitochondrial DNA

21 January 2018

1 reference

Double-strand breaks of mouse muscle mtDNA promote large deletions similar to multiple mtDNA deletions in humans

21 January 2018

1 reference

Extension of murine life span by overexpression of catalase targeted to mitochondria

21 January 2018

1 reference

Endogenously oxidized mitochondrial DNA induces in vivo and in vitro inflammatory responses.

21 January 2018

1 reference

Electrophile and oxidant damage of mitochondrial DNA leading to rapid evolution of homoplasmic mutations

21 January 2018

1 reference

An mtDNA mutation in the initiation codon of the cytochrome C oxidase subunit II gene results in lower levels of the protein and a mitochondrial encephalomyopathy

21 January 2018

1 reference

Abnormal expression of the genes involved in cytokine networks and mitochondrial function in systemic juvenile idiopathic arthritis identified by DNA microarray analysis

21 January 2018

1 reference

Intracellular signaling by reactive oxygen species during hypoxia in cardiomyocytes.

21 January 2018

1 reference

Effects of mitochondrial potassium channel and membrane potential on hypoxic human pulmonary artery smooth muscle cells.

21 January 2018

1 reference

Oxidative stress induces angiogenesis by activating TLR2 with novel endogenous ligands

21 January 2018

1 reference

Treatment of murine collagen-induced arthritis by ex vivo extracellular superoxide dismutase gene transfer

21 January 2018

1 reference

Dephosphorylated hypoxia-inducible factor 1alpha as a mediator of p53-dependent apoptosis during hypoxia

21 January 2018

1 reference

Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism

21 January 2018

1 reference

The hydroxylase inhibitor dimethyloxalylglycine is protective in a murine model of colitis.

21 January 2018

1 reference

Activation of hypoxia-inducible factor attenuates renal injury in rat remnant kidney

21 January 2018

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Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/ART.30395

1 reference

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28 January 2020

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