(Q59183364)

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Characterization of the Taxol Binding Site on the Microtubule

scientific article published in Journal of Biological Chemistry

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scholarly article

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2 November 2019

Characterization of the Taxol binding site on the microtubule. Identification of Arg(282) in beta-tubulin as the site of photoincorporation of a 7-benzophenone analogue of Taxol (English)

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2 November 2019

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4

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2 November 2019

author name string

S Rao

1

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2 November 2019

L He

2

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2 November 2019

S Chakravarty

3

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2 November 2019

G A Orr

5

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2 November 2019

S B Horwitz

6

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2 November 2019

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publication date

1 December 1999

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2 November 2019

number of pages

5

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Journal of Biological Chemistry

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2 November 2019

274

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2 November 2019

37990-37994

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2 November 2019

53

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2 November 2019

Paclitaxel (taxol)

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https://api.crossref.org/works/10.1074%2FJBC.274.53.37990

21 January 2018

Taxol binds to cellular microtubules

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37990

21 January 2018

Direct photoaffinity labeling of tubulin with taxol

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37990

21 January 2018

Promotion of microtubule assembly in vitro by taxol

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21 January 2018

Taxol binds to polymerized tubulin in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37990

21 January 2018

Assembly of purified GDP-tubulin into microtubules induced by taxol and taxotere: reversibility, ligand stoichiometry, and competition.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37990

21 January 2018

Taxol stabilizes microtubules in mouse fibroblast cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37990

21 January 2018

Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37990

21 January 2018

Characterization of the taxol binding site on the microtubule. 2-(m-Azidobenzoyl)taxol photolabels a peptide (amino acids 217-231) of beta-tubulin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37990

21 January 2018

Structure of the alpha beta tubulin dimer by electron crystallography

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37990

21 January 2018

Identification of the domains of photoincorporation of the 3'- and 7-benzophenone analogues of taxol in the carboxyl-terminal half of murine mdr1b P-glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37990

21 January 2018

New photoaffinity analogs of paclitaxel

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37990

21 January 2018

Microtubule Assembly in the Absence of Added Nucleotides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37990

21 January 2018

Turbidimetric studies of the in vitro assembly and disassembly of porcine neurotubules.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37990

21 January 2018

Cyanogen bromide cleavage and proteolytic peptide mapping of proteins immobilized to membranes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37990

21 January 2018

Crystal and molecular structure of paclitaxel (taxol).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37990

21 January 2018

Complete amino acid sequence of beta-tubulin from porcine brain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37990

21 January 2018

Identification of conserved isotype-defining variable region sequences for four vertebrate beta tubulin polypeptide classes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37990

21 January 2018

High-resolution model of the microtubule

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37990

21 January 2018

Benzophenone photophores in biochemistry.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37990

21 January 2018

Differential Effects of Paclitaxel (Taxol) Analogs Modified at Positions C-2, C-7, and C-3' on Tubulin Polymerization and Polymer Stabilization: Identification of a Hyperactive Paclitaxel Derivative

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37990

21 January 2018

How Taxol stabilises microtubule structure.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37990

21 January 2018

Paclitaxel-resistant human ovarian cancer cells have mutant beta-tubulins that exhibit impaired paclitaxel-driven polymerization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37990

21 January 2018

A beta-tubulin leucine cluster involved in microtubule assembly and paclitaxel resistance.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37990

21 January 2018

Paclitaxel resistance in non-small-cell lung cancer associated with beta-tubulin gene mutations

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37990

21 January 2018

Identifiers

10.1074/JBC.274.53.37990

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10608867%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10608867%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

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