(Q59183426)

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Synthesis and biological activity of novel 3′-trifluoromethyl taxoids

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Synthesis and biological activity of novel 3′-trifluoromethyl taxoids (English)

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1

Iwao Ojima

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John C. Slater

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2

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Paula Pera

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3

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Jean M. Veith

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4

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Ahmed Abouabdellah

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5

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Jean-Pierre Bégué

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6

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Ralph J. Bernacki

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7

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language of work or name

English

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publication date

January 1997

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published in

Bioorganic & Medicinal Chemistry Letters

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volume

7

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issue

2

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page(s)

133-138

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cites work

Plant antitumor agents. VI. The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia

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Promotion of microtubule assembly in vitro by taxol

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Studies With RP 56976 (Taxotere): A Semisynthetic Analogue of Taxol

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Paclitaxel (Taxol) and docetaxel (Taxotere): not simply two of a kind

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Syntheses and structure-activity relationships of the second-generation antitumor taxoids: exceptional activity against drug-resistant cancer cells

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New colorimetric cytotoxicity assay for anticancer-drug screening

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Modulation of multidrug resistance: at the threshold

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Conformation of a water-soluble derivative of taxol in water by 2D-NMR spectroscopy

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Taxol: quantitative internuclear proton-proton distances in CDCl3 solution from nOe data: 2D nmr ROESY buildup rates at 500 MHz

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Identifiers

DOI

10.1016/S0960-894X(96)00595-1

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(Q59183426)

Synthesis and biological activity of novel 3′-trifluoromethyl taxoids

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