(Q59349434)

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Single HIV-1 Imaging Reveals Progression of Infection through CA-Dependent Steps of Docking at the Nuclear Pore, Uncoating, and Nuclear Transport

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Single HIV-1 Imaging Reveals Progression of Infection through CA-Dependent Steps of Docking at the Nuclear Pore, Uncoating, and Nuclear Transport (English)

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Ashwanth C Francis

object named as

Ashwanth C Francis

1

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Gregory B Melikyan

2

object named as

Gregory B Melikyan

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language of work or name

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publication date

11 April 2018

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Cell Host & Microbe

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23

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4

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536-548.e6

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describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5901770/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aberrant Gag protein composition of a human immunodeficiency virus type 1 vif mutant produced in primary lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of CCR5 and CD4 cell surface concentrations on infections by macrophagetropic isolates of human immunodeficiency virus type 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiviral activity of the proteasome on incoming human immunodeficiency virus type 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Degradation of HIV-1 integrase by the N-end rule pathway

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https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of a human immunodeficiency virus type 1 core of optimal stability is crucial for viral replication

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https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular transport of human immunodeficiency virus type 1 integrase

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel single-cell-level phenotypic assay for residual drug susceptibility and reduced replication capacity of drug-resistant human immunodeficiency virus type 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The stoichiometry of Gag protein in HIV-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Target cell cyclophilin A modulates human immunodeficiency virus type 1 infectivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclophilin interactions with incoming human immunodeficiency virus type 1 capsids with opposing effects on infectivity in human cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of lysosome and proteasome function enhances human immunodeficiency virus type 1 infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative four-dimensional tracking of cytoplasmic and nuclear HIV-1 complexes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 DNA Flap formation promotes uncoating of the pre-integration complex at the nuclear pore

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluorogen-activating single-chain antibodies for imaging cell surface proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The structural biology of HIV assembly

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 pre-integration complexes selectively target decondensed chromatin in the nuclear periphery

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A one-step SYBR Green I-based product-enhanced reverse transcriptase assay for the quantitation of retroviruses in cell culture supernatants

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potent inhibition of HIV-1 by TRIM5-cyclophilin fusion proteins engineered from human components

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flexible use of nuclear import pathways by HIV-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV Capsid is a Tractable Target for Small Molecule Therapeutic Intervention

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The requirement for nucleoporin NUP153 during human immunodeficiency virus type 1 infection is determined by the viral capsid.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complementary assays reveal a relationship between HIV-1 uncoating and reverse transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human immunodeficiency virus type 1 capsid mutation N74D alters cyclophilin A dependence and impairs macrophage infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Second-site suppressors of HIV-1 capsid mutations: restoration of intracellular activities without correction of intrinsic capsid stability defects

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Icy: an open bioimage informatics platform for extended reproducible research.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The host proteins transportin SR2/TNPO3 and cyclophilin A exert opposing effects on HIV-1 uncoating.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single-cell imaging of HIV-1 provirus (SCIP).

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for biphasic uncoating during HIV-1 infection from a novel imaging assay

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nucleoporin NUP153 phenylalanine-glycine motifs engage a common binding pocket within the HIV-1 capsid protein to mediate lentiviral infectivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 evades innate immune recognition through specific cofactor recruitment

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear import of APOBEC3F-labeled HIV-1 preintegration complexes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A model for cofactor use during HIV-1 reverse transcription and nuclear entry

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 uncoating: connection to nuclear entry and regulation by host proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Second generation imaging of nuclear/cytoplasmic HIV-1 complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improved vectors and genome-wide libraries for CRISPR screening

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Host cofactors and pharmacologic ligands share an essential interface in HIV-1 capsid that is lost upon disassembly.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative microscopy of functional HIV post-entry complexes reveals association of replication with the viral capsid

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural basis of HIV-1 capsid recognition by PF74 and CPSF6.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complementary Assays Reveal a Low Level of CA Associated with Viral Complexes in the Nuclei of HIV-1-Infected Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 capsid: the multifaceted key player in HIV-1 infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct Visualization of HIV-1 Replication Intermediates Shows that Capsid and CPSF6 Modulate HIV-1 Intra-nuclear Invasion and Integration

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Time-Resolved Imaging of Single HIV-1 Uncoating In Vitro and in Living Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamic Oligomerization of Integrase Orchestrates HIV Nuclear Entry

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early cytoplasmic uncoating is associated with infectivity of HIV-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamics and regulation of nuclear import and nuclear movements of HIV-1 complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An improved labeling strategy enables automated detection of single-virus fusion and assessment of HIV-1 protease activity in single virions

1 reference

https://pubmed.ncbi.nlm.nih.gov/29649444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.CHOM.2018.03.009

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