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Selective inhibitors of apoptotic caspases: implications for novel therapeutic strategies
scientific article published on 01 January 2001
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11166256
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11166256%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
title
Selective inhibitors of apoptotic caspases: implications for novel therapeutic strategies
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11166256
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11166256%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
main subject
apoptotic process
1 reference
based on heuristic
inferred from title
author
BethAnn McLaughlin
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11166256
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11166256%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
author name string
M E. Nuttall
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11166256
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11166256%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
D Lee
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11166256
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11166256%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
J A. Erhardt
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11166256
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11166256%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
publication date
1 January 2001
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11166256
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11166256%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
published in
Drug Discovery Today
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11166256
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11166256%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
volume
6
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11166256
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11166256%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
issue
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11166256
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11166256%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
page(s)
85-91
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11166256
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11166256%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
cites work
Caspases: enemies within
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mammalian caspases: structure, activation, substrates, and functions during apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of human caspases by peptide-based and macromolecular inhibitors
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Non-specific effects of methyl ketone peptide inhibitors of caspases
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential requirement for caspase 9 in apoptotic pathways in vivo.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defects in regulation of apoptosis in caspase-2-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase inhibitors.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Emerging roles of caspase-3 in apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspases: killer proteases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Conformationally constrained inhibitors of caspase-1 (interleukin-1 beta converting enzyme) and of the human CED-3 homologue caspase-3 (CPP32, apopain)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Potent and selective nonpeptide inhibitors of caspases 3 and 7 inhibit apoptosis and maintain cell functionality
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of caspase-3-like activity prevents apoptosis while retaining functionality of human chondrocytes in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Osteoarthritis chondrocytes die by apoptosis: A possible pathway for osteoarthritis pathology
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Soluble Fas ligand in the joints of patients with rheumatoid arthritis and osteoarthritis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Parathyroid hormone-related peptide and the parathyroid hormone/parathyroid hormone-related peptide receptor in skeletal development.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis of chondrocytes in transgenic mice lacking collagen II
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chondrocyte apoptosis and nitric oxide production during experimentally induced osteoarthritis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuroprotection by the inhibition of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspases and neurodegeneration: on the cutting edge of new therapeutic approaches.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of CPP32-like caspases contributes to neuronal apoptosis and neurological dysfunction after traumatic brain injury.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytochrome c release and caspase activation in traumatic axonal injury
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-3 mediated neuronal death after traumatic brain injury in rats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of caspase-1-like activity by Ac-Tyr-Val-Ala-Asp-chloromethyl ketone induces long-lasting neuroprotection in cerebral ischemia through apoptosis reduction and decrease of proinflammatory cytokines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of caspase-3 in beta-amyloid-induced apoptosis of cultured rat cortical neurons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibiting caspase cleavage of huntingtin reduces toxicity and aggregate formation in neuronal and nonneuronal cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aurintricarboxylic acid rescues PC12 cells and sympathetic neurons from cell death caused by nerve growth factor deprivation: correlation with suppression of endonuclease activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nerve growth factor withdrawal-induced cell death in neuronal PC12 cells resembles that in sympathetic neurons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A system for characterizing cellular and molecular events in programmed neuronal cell death.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of CPP32-like activity in PC12 cells by withdrawal of trophic support. Dissociation from apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Need for caspases in apoptosis of trophic factor-deprived PC12 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-2 (Nedd-2) processing and death of trophic factor-deprived PC12 cells and sympathetic neurons occur independently of caspase-3 (CPP32)-like activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspases: intracellular signaling by proteolysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis in the rheumatic diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Blocking apoptosis prevents blindness in Drosophila retinal degeneration mutants.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901601-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1359-6446(00)01601-9
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11166256
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11166256%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
PubMed publication ID
11166256
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11166256
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11166256%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
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