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English
Mechanism of leptin expression in breast cancer cells: role of hypoxia-inducible factor-1α
scientific article published on 23 July 2007
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
17653093
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17653093%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
title
Mechanism of leptin expression in breast cancer cells: role of hypoxia-inducible factor-1alpha
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
17653093
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17653093%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
main subject
hypoxia
1 reference
based on heuristic
inferred from title
breast cancer
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inferred from title
author
Sandra Cascio
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
17653093
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17653093%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
Antonio Giordano
series ordinal
6
1 reference
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Europe PubMed Central
PubMed ID
17653093
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17653093%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
author name string
Bartella V
series ordinal
2
1 reference
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Europe PubMed Central
PubMed ID
17653093
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17653093%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
Auriemma A
series ordinal
3
1 reference
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Europe PubMed Central
PubMed ID
17653093
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17653093%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
Johannes GJ
series ordinal
4
1 reference
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Europe PubMed Central
PubMed ID
17653093
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17653093%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
Russo A
series ordinal
5
1 reference
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Europe PubMed Central
PubMed ID
17653093
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17653093%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
Surmacz E
series ordinal
7
1 reference
stated in
Europe PubMed Central
PubMed ID
17653093
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17653093%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
language of work or name
English
0 references
publication date
23 July 2007
1 reference
stated in
Europe PubMed Central
PubMed ID
17653093
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17653093%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
published in
Oncogene
1 reference
stated in
Europe PubMed Central
PubMed ID
17653093
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17653093%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
volume
27
1 reference
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Europe PubMed Central
PubMed ID
17653093
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17653093%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
page(s)
540-547
1 reference
stated in
Europe PubMed Central
PubMed ID
17653093
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17653093%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
issue
4
1 reference
stated in
Europe PubMed Central
PubMed ID
17653093
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17653093%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
exact match
https://scigraph.springernature.com/pub.10.1038/sj.onc.1210660
0 references
cites work
Leptin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210660
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Obesity and cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210660
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin-like growth factor 1 differentially regulates estrogen receptor-dependent transcription at estrogen response element and AP-1 sites in breast cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210660
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glucocorticoids induce the expression of the leptin gene through a non-classical mechanism of transcriptional activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210660
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of transcription by hypoxia requires a multiprotein complex that includes hypoxia-inducible factor 1, an adjacent transcription factor, and p300/CREB binding protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210660
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transactivation of erbB2 by short and long isoforms of leptin receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210660
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased expression of leptin and the leptin receptor as a marker of breast cancer progression: possible role of obesity-related stimuli.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210660
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Leptin interferes with the effects of the antiestrogen ICI 182,780 in MCF-7 breast cancer cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210660
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Leptin and cancer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210660
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypoxia-Inducible Factor-1 Expression Predicts a Poor Response to Primary Chemoendocrine Therapy and Disease-Free Survival in Primary Human Breast Cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210660
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Leptin signaling promotes the growth of mammary tumors and increases the expression of vascular endothelial growth factor (VEGF) and its receptor type two (VEGF-R2)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210660
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIF-1alpha, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210660
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypoxia-inducible factor 1 transactivates the human leptin gene promoter
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210660
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of angiogenesis by hypoxia-inducible factor 1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210660
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enhanced expression of leptin and leptin receptor (OB-R) in human breast cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210660
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
AGA technical review on obesity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210660
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypoxia inducible factor pathways as targets for functional foods
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210660
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210660
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of leptin promoter function by Sp1, C/EBP, and a novel factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210660
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synergistic effects of hypoxia and insulin are regulated by different transcriptional elements of the human leptin promoter
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210660
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Leptin gene expression in human preadipocytes is switched on by maturation-induced demethylation of distinct CpGs in its proximal promoter
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210660
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypoxia-induced activation of the retinoic acid receptor-related orphan receptor alpha4 gene by an interaction between hypoxia-inducible factor-1 and Sp1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210660
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The adipocyte specific transcription factor C/EBPalpha modulates human ob gene expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210660
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear insulin receptor substrate 1 interacts with estrogen receptor alpha at ERE promoters
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210660
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Akt1 activation can augment hypoxia-inducible factor-1alpha expression by increasing protein translation through a mammalian target of rapamycin-independent pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210660
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of obesity on presentation of breast cancer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210660
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypoxia signalling in cancer and approaches to enforce tumour regression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210660
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Messenger RNA expression of leptin and leptin receptors and their prognostic value in 322 human primary breast cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210660
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Leptin and leptin receptor polymorphisms are associated with increased risk and poor prognosis of breast carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210660
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Obesity hormone leptin: a new target in breast cancer?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210660
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of hypoxia-inducible factor (HIF)-1 activity and expression of HIF hydroxylases in response to insulin-like growth factor I.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210660
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential prognostic impact of hypoxia induced and diffuse HIF-1alpha expression in invasive breast cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210660
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human leptin: from an adipocyte hormone to an endocrine mediator
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210660
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.ONC.1210660
1 reference
stated in
Europe PubMed Central
PubMed ID
17653093
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17653093%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
PubMed ID
17653093
1 reference
stated in
Europe PubMed Central
PubMed ID
17653093
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17653093%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
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