(Q59602417)

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Autocrine production of TGF-β confers resistance to apoptosis after an epithelial–mesenchymal transition process in hepatocytes: Role of EGF receptor ligands

scientific article published on 07 June 2006

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26 December 2019

Autocrine production of TGF-beta confers resistance to apoptosis after an epithelial-mesenchymal transition process in hepatocytes: Role of EGF receptor ligands (English)

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26 December 2019

apoptotic process

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based on heuristic

inferred from title

Alberto Alvarez-Barrientos

3

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26 December 2019

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26 December 2019

Margarita Fernández

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26 December 2019

Aránzazu Sánchez

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26 December 2019

Isabel Fabregat

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26 December 2019

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Gaelle Del Castillo

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26 December 2019

Miguel M Murillo

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7 June 2006

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26 December 2019

Experimental Cell Research

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26 December 2019

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26 December 2019

2860-2871

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26 December 2019

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26 December 2019

Epithelial-mesenchymal transitions in development and pathologies

1 reference

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The snail superfamily of zinc-finger transcription factors

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The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression

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Correlation of Snail expression with histological grade and lymph node status in breast carcinomas

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Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer

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TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: involvement of type I receptors

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Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: mechanisms for epithelial mesenchymal transitions.

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Apoptosis Induced by Transforming Growth Factor- in Fetal Hepatocyte Primary Cultures

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Apoptotic Response to TGF-$beta; in Fetal Hepatocytes Depends upon Their State of Differentiation

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Snail blocks the cell cycle and confers resistance to cell death

1 reference

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7 January 2021

Epidermal growth factor, but not hepatocyte growth factor, suppresses the apoptosis induced by transforming growth factor-beta in fetal hepatocytes in primary culture

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Interleukin-6 inhibits transforming growth factor-beta-induced apoptosis through the phosphatidylinositol 3-kinase/Akt and signal transducers and activators of transcription 3 pathways

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Epidermal Growth Factor Impairs the Cytochrome C/Caspase-3 Apoptotic Pathway Induced by Transforming Growth Factorβ in Rat Fetal Hepatocytes Via a Phosphoinositide 3-Kinase–Dependent Pathway

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Transforming growth factor-beta activates both pro-apoptotic and survival signals in fetal rat hepatocytes

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Involvement of c-Src kinase in the regulation of TGF-beta1-induced apoptosis

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Involvement of EGF receptor and c-Src in the survival signals induced by TGF-beta1 in hepatocytes

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7 January 2021

Epithelial-mesenchymal transition of cultured rat neonatal hepatocytes is differentially regulated in response to epidermal growth factor and dimethyl sulfoxide

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7 January 2021

Establishment, characterization, and long-term maintenance of cultures of human fetal hepatocytes.

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The role of TGF-beta and Wnt signaling in gastrointestinal stem cells and cancer

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Transforming growth factor beta1 (TGF-beta1) promotes endothelial cell survival during in vitro angiogenesis via an autocrine mechanism implicating TGF-alpha signaling

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7 January 2021

Conditional overexpression of active transforming growth factor beta1 in vivo accelerates metastases of transgenic mammary tumors

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Tumor-suppressive and promoting function of transforming growth factor beta

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Activation of caspase-8 in transforming growth factor-beta-induced apoptosis of human hepatoma cells

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7 January 2021

cIAP-1, but not XIAP, is cleaved by caspases during the apoptosis induced by TGF-beta in fetal rat hepatocytes

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Transforming growth factor-alpha inhibits the intrinsic pathway of c-Myc-induced apoptosis through activation of nuclear factor-kappaB in murine hepatocellular carcinomas

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Transforming growth factor alpha may be a physiological regulator of liver regeneration by means of an autocrine mechanism

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High expression of heparin-binding EGF-like growth factor in rat hepatocarcinogenesis

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Expression of heparin-binding epidermal growth factor-like growth factor in the hepatocytes of fibrotic rat liver during hepatocarcinogenesis

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Novel role for amphiregulin in protection from liver injury

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Dual role for TGF-beta1 in apoptosis

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Transforming growth factor beta1 rescues serum deprivation-induced apoptosis via the mitogen-activated protein kinase (MAPK) pathway in macrophages

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Activation of the pro-survival phosphatidylinositol 3-kinase/AKT pathway by transforming growth factor-beta1 in mesenchymal cells is mediated by p38 MAPK-dependent induction of an autocrine growth factor.

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Secreted transforming growth factor beta2 activates NF-kappaB, blocks apoptosis, and is essential for the survival of some tumor cells

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Autocrine TGFbeta supports growth and survival of human breast cancer MDA-MB-231 cells

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Raf induces TGFbeta production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells

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beta-Catenin and TGFbeta signalling cooperate to maintain a mesenchymal phenotype after FosER-induced epithelial to mesenchymal transition.

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Blockade of TGF-beta inhibits mammary tumor cell viability, migration, and metastases.

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Identifiers

10.1016/J.YEXCR.2006.05.017

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26 December 2019

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26 December 2019

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