(Q36241260)

13 August 2017

1 reference

title

The role of TGF-beta and Wnt signaling in gastrointestinal stem cells and cancer (English)

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13 August 2017

Lopa Mishra

1

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13 August 2017

Kirti Shetty

2

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13 August 2017

Yi Tang

3

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13 August 2017

August Stuart

4

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13 August 2017

Stephen W Byers

5

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13 August 2017

language of work or name

English

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publication date

1 August 2005

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13 August 2017

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13 August 2017

volume

24

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13 August 2017

issue

37

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13 August 2017

page(s)

5775-5789

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1208924

13 August 2017

exact match

0 references

cites work

Mads and Smads in TGF beta signalling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

21 January 2018

Pancreatic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

Gastrointestinal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

Initiation and early patterning of the endoderm

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

21 January 2018

The renaissance of GSK3

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

Drosophila beta spectrin functions independently of alpha spectrin to polarize the Na,K ATPase in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

APC, signal transduction and genetic instability in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

Transforming growth factor: signal transduction pathways, cell cycle mediation, and effects on hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

In vivo derivation of glucose-competent pancreatic endocrine cells from bone marrow without evidence of cell fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

Differential expression of transforming growth factors alpha and beta in rat intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

Association of Smads with lymphoid enhancer binding factor 1/T cell-specific factor mediates cooperative signaling by the transforming growth factor-beta and wnt pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

Genes, Signals, and Lineages in Pancreas Development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

Mutations of the APC (adenomatous polyposis coli) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

Identification of functional domains in the neuronal Cdk5 activator protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

TGF-beta-mediated cell cycle arrest of HPV16-immortalized human ectocervical cells correlates with decreased E6/E7 mRNA and increased p53 and p21(WAF-1) expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

Live and let die in the intestinal epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

Mad upregulation and Id2 repression accompany transforming growth factor (TGF)-beta-mediated epithelial cell growth suppression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

Intestinal epithelial cell differentiation: new insights from mice, flies and nematodes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

Immunolocalization of the fodrin, E-cadherin, and beta-catenin adhesion complex in infiltrating ductal carcinoma of the breast-comparison with an in vitro model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

The transforming growth factor-betas: past, present, and future

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

Bone marrow to liver: the blood of Prometheus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

Demonstration that mutation of the type II transforming growth factor beta receptor inactivates its tumor suppressor activity in replication error-positive colon carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

The origin and liver repopulating capacity of murine oval cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

Vertebrate endoderm development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

Germline mutations in BMPR1A/ALK3 cause a subset of cases of juvenile polyposis syndrome and of Cowden and Bannayan-Riley-Ruvalcaba syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

Hepatocytes from non-hepatic adult stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

FoxOs at the crossroads of cellular metabolism, differentiation, and transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Transforming growth factor beta type II receptor gene mutations in adenomas from hereditary nonpolyposis colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Fusion of bone-marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Regulation of intestinal epithelial cell growth by transforming growth factor type beta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

The spectrin-based membrane skeleton as a membrane protein-sorting machine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Spectrin and ankyrin-based pathways: metazoan inventions for integrating cells into tissues

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

The Differentiated State of Normal and Malignant Cells or How to Define a “Normal” Cell in Culture

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

How does the extracellular matrix direct gene expression?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Colossal crypts bordering colon adenomas in Apc(Min) mice express full-length Apc.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

The evolving concept of a stem cell: entity or function?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

TGFbeta1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

TGF-beta signaling in tumor suppression and cancer progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Wounding and its role in RSV-mediated tumor formation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Microtubule binding to Smads may regulate TGF beta activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Differential effects of a labial mutation on the development, structure, and function of stomach acid-secreting cells in Drosophila melanogaster larvae and adults.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Interaction between Smad7 and beta-catenin: importance for transforming growth factor beta-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Interdependent SMAD and JNK signaling in transforming growth factor-beta-mediated transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

A genetic model for colorectal tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

1 reference

7 January 2021

Axin facilitates Smad3 activation in the transforming growth factor beta signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Paneth cells--guardians of the gut cell hatchery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Identification and characterization of the familial adenomatous polyposis coli gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

De novo crypt formation and juvenile polyposis on BMP inhibition in mouse intestine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

A cellular framework for gut-looping morphogenesis in zebrafish.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Differentiation of the mouse hepatic primordium. II. Extrinsic origin of the haemopoietic cell line

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Mutations in the SMAD4/DPC4 gene in juvenile polyposis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

APC mutations in colorectal tumors with mismatch repair deficiency

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Regulation of the TGFbeta signalling pathway by ubiquitin-mediated degradation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Del(10)(q22.3q24.1) associated with juvenile polyposis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Cancer statistics, 2002

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

ONCOGENESIS: Landscaping the Cancer Terrain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Hepatocytes and epithelial cells of donor origin in recipients of peripheral-blood stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Purified hematopoietic stem cells can differentiate into hepatocytes in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Posterior gut development in Drosophila: a model system for identifying genes controlling epithelial morphogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Hepatic progenitor cells in hepatocellular adenomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Deep intralobular extension of human hepatic 'progenitor cells' correlates with parenchymal inflammation in chronic viral hepatitis: can 'progenitor cells' migrate?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

TGF-beta-activated Smad3 represses MEF2-dependent transcription in myogenic differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Hereditary colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

The intestinal epithelial stem cell

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

G1 cell-cycle control and cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

TGFbeta signaling in growth control, cancer, and heritable disorders

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Occlusion and subsequent re-canalization in early duodenal development of human embryos: integrated organogenesis and histogenesis through a possible epithelial-mesenchymal interaction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Loss of cooperative function of transforming growth factor-beta signaling proteins, smad3 with embryonic liver fodrin, a beta-spectrin, in primary biliary cirrhosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Higher frequency of Smad4 gene mutation in human colorectal cancer with distant metastasis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Expansion of Hepatic and Hematopoietic Stem Cells Utilizing Mouse Embryonic Liver Explants

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Differential trafficking of transforming growth factor-beta receptors and ligand in polarized epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Smad7: a new key player in TGF-beta-associated disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Phenotypic and genotypic characteristics of aberrant crypt foci in human colorectal mucosa

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

TGFbeta signaling is necessary for carcinoma cell invasiveness and metastasis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Bone marrow as a potential source of hepatic oval cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

APC mutations occur early during colorectal tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Cancer. Respect thy neighbor!

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Self-renewal and cancer of the gut: two sides of a coin.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Phenotypic and molecular characteristics of hyperplastic polyposis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Orofacial and gastrointestinal hyperplasia and neoplasia in smad4+/- and elf+/-/smad4+/- mutant mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

TGF-beta signaling from receptors to the nucleus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Molecular mechanisms of development of the gastrointestinal tract

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Progenitor cells in diseased human liver

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

1 reference

7 January 2021

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Top-down morphogenesis of colorectal tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Mediation of wound-related Rous sarcoma virus tumorigenesis by TGF-beta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Peptide growth factors are multifunctional

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Stem cells find their niche

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

A glimpse into the molecular entrails of endoderm formation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

No organ left behind: tales of gut development and evolution

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

The stromal proteinase MMP3/stromelysin-1 promotes mammary carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Mutation analysis of coding sequences of the entire transforming growth factor beta type II receptor gene in sporadic human colon cancer using genomic DNA and intron primers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Gastro-intestinal tumorigenesis in Smad4 mutant mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Transforming growth factor-beta1 is a new form of tumor suppressor with true haploid insufficiency.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Disruption of transforming growth factor-beta signaling in ELF beta-spectrin-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Transforming growth factor-beta suppresses nonmetastatic colon cancer through Smad4 and adaptor protein ELF at an early stage of tumorigenesis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Derivation of hepatocytes from bone marrow cells in mice after radiation-induced myeloablation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

The canals of Hering and hepatic stem cells in humans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Microsatellite instability in cancer of the proximal colon

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Liver stem cells--prospects for clinical use.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Transplanted bone marrow regenerates liver by cell fusion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Disruption of the antiproliferative TGF-beta signaling pathways in human pancreatic cancer cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Stable reprogrammed heterokaryons form spontaneously in Purkinje neurons after bone marrow transplant

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Smad proteins and hepatocyte growth factor control parallel regulatory pathways that converge on beta1-integrin to promote normal liver development.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Regulation of Smad activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Haploid loss of the tumor suppressor Smad4/Dpc4 initiates gastric polyposis and cancer in mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Inactivation of p21WAF1/cip1 enhances intestinal tumor formation in Muc2-/- mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

The tumor suppressor SMAD4/DPC4 is essential for epiblast proliferation and mesoderm induction in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Molecular genetics of early liver development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Smad3 mutant mice develop metastatic colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208924

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1208924

1 reference

13 August 2017

1 reference