(Q59797956)

1

0 references

Yoshimasa Saito

2

0 references

Kazuki Nogami

3

0 references

Yohei Kajiyama

4

0 references

Yukana Suzuki

5

0 references

Yasuhiro Kawase

6

0 references

Toshiaki Nakaoka

7

0 references

Toshihide Muramatsu

8

0 references

Masaki Kimura

9

0 references

Hidetsugu Saito

NPJ aging and mechanisms of disease

10

0 references

language of work or name

English

0 references

publication date

2019

0 references

published in

0 references

volume

5

0 references

issue

1

0 references

page(s)

1

0 references

exact match

https://scigraph.springernature.com/pub.10.1038/s41514-018-0031-5

0 references

cites work

Hayflick, his limit, and cellular ageing.

1 reference

https://api.crossref.org/works/10.1038%2FS41514-018-0031-5

7 January 2021

Stem cell aging: mechanisms, regulators and therapeutic opportunities

1 reference

https://api.crossref.org/works/10.1038%2FS41514-018-0031-5

7 January 2021

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

1 reference

https://api.crossref.org/works/10.1038%2FS41514-018-0031-5

7 January 2021

Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro

1 reference

https://api.crossref.org/works/10.1038%2FS41514-018-0031-5

7 January 2021

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

1 reference

https://api.crossref.org/works/10.1038%2FS41514-018-0031-5

7 January 2021

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

1 reference

https://api.crossref.org/works/10.1038%2FS41514-018-0031-5

7 January 2021

In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration.

1 reference

https://api.crossref.org/works/10.1038%2FS41514-018-0031-5

7 January 2021

Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis

1 reference

https://api.crossref.org/works/10.1038%2FS41514-018-0031-5

7 January 2021

R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling

1 reference

https://api.crossref.org/works/10.1038%2FS41514-018-0031-5

7 January 2021

Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

1 reference

https://api.crossref.org/works/10.1038%2FS41514-018-0031-5

7 January 2021

Organoid cultures derived from patients with advanced prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41514-018-0031-5

7 January 2021

Organoid models of human and mouse ductal pancreatic cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41514-018-0031-5

7 January 2021

Modeling colorectal cancer using CRISPR-Cas9-mediated engineering of human intestinal organoids.

1 reference

https://api.crossref.org/works/10.1038%2FS41514-018-0031-5

7 January 2021

Human primary liver cancer-derived organoid cultures for disease modeling and drug screening.

1 reference

https://api.crossref.org/works/10.1038%2FS41514-018-0031-5

7 January 2021

Inhibition of DNA Methylation Suppresses Intestinal Tumor Organoids by Inducing an Anti-Viral Response.

1 reference

https://api.crossref.org/works/10.1038%2FS41514-018-0031-5

7 January 2021

Induction of differentiation of intrahepatic cholangiocarcinoma cells to functional hepatocytes using an organoid culture system.

1 reference

https://api.crossref.org/works/10.1038%2FS41514-018-0031-5

7 January 2021

Canonical Wnt Signaling Ameliorates Aging of Intestinal Stem Cells.

1 reference

https://api.crossref.org/works/10.1038%2FS41514-018-0031-5

7 January 2021

OLFM4 is a robust marker for stem cells in human intestine and marks a subset of colorectal cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FS41514-018-0031-5

7 January 2021

Dnmt1 is essential to maintain progenitors in the perinatal intestinal epithelium

1 reference

https://api.crossref.org/works/10.1038%2FS41514-018-0031-5

7 January 2021

Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice

1 reference

https://api.crossref.org/works/10.1038%2FS41514-018-0031-5

7 January 2021

Ageing and the telomere connection: An intimate relationship with inflammation

1 reference

https://api.crossref.org/works/10.1038%2FS41514-018-0031-5

7 January 2021

Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice

1 reference

https://api.crossref.org/works/10.1038%2FS41514-018-0031-5

7 January 2021

NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR.

1 reference

https://api.crossref.org/works/10.1038%2FS41514-018-0031-5

7 January 2021

Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation

1 reference

https://api.crossref.org/works/10.1038%2FS41514-018-0031-5

7 January 2021

Alterations of epigenetics and microRNA in hepatocellular carcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FS41514-018-0031-5

7 January 2021

Cryosectioning the intestinal crypt-villus axis: an ex vivo method to study the dynamics of epigenetic modifications from stem cells to differentiated cells.

1 reference

https://api.crossref.org/works/10.1038%2FS41514-018-0031-5

7 January 2021

SIRT1 and caloric restriction: an insight into possible trade-offs between robustness and frailty

1 reference

https://api.crossref.org/works/10.1038%2FS41514-018-0031-5

7 January 2021

The NAD World 2.0: the importance of the inter-tissue communication mediated by NAMPT/NAD+/SIRT1 in mammalian aging and longevity control

1 reference

https://api.crossref.org/works/10.1038%2FS41514-018-0031-5

7 January 2021

Slowing ageing by design: the rise of NAD(+) and sirtuin-activating compounds

1 reference

https://api.crossref.org/works/10.1038%2FS41514-018-0031-5

7 January 2021

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

1 reference

https://api.crossref.org/works/10.1038%2FS41514-018-0031-5

7 January 2021