(Q59799703)

Nicole Déglon

9

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Vincent Deramecourt

8

Vincent Deramecourt

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Claude-Alain Maurage

10

Claude-Alain Maurage

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Bradley Hyman

12

Bradley T Hyman

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Matthew Frosch

11

Matthew P Frosch

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author name string

Séverine Bégard

2

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Raphaëlle Caillierez

3

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Cédrick Lachaud

4

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Sébastien Carrier

5

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Sarah Lieger

6

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Jose A Gonzalez

7

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Morvane Colin

13

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Luc Buée

Acta Neuropathologica Communications

14

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language of work or name

English

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publication date

29 November 2018

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published in

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volume

6

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issue

1

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page(s)

132

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exact match

https://scigraph.springernature.com/pub.10.1186/s40478-018-0637-7

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cites work

Monoclonal antibodies with selective specificity for Alzheimer Tau are directed against phosphatase-sensitive epitopes

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12 December 2020

Neuropathological stageing of Alzheimer-related changes

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12 December 2020

Tau protein binds to microtubules through a flexible array of distributed weak sites

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12 December 2020

Tau consists of a set of proteins with repeated C-terminal microtubule-binding domains and variable N-terminal domains

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12 December 2020

Microtubule-associated protein tau. A component of Alzheimer paired helical filaments.

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12 December 2020

Oxidation of cysteine-322 in the repeat domain of microtubule-associated protein tau controls the in vitro assembly of paired helical filaments

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12 December 2020

Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: distinction between PHF-like immunoreactivity and microtubule binding.

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12 December 2020

Progressive supranuclear palsy: a clinicopathological study of 21 cases

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12 December 2020

Alz-50 and MC-1, a new monoclonal antibody raised to paired helical filaments, recognize conformational epitopes on recombinant tau.

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12 December 2020

Tau proteins with FTDP-17 mutations have a reduced ability to promote microtubule assembly

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12 December 2020

The biochemical pathway of neurofibrillary degeneration in aging and Alzheimer's disease.

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12 December 2020

Sequence requirements for formation of conformational variants of tau similar to those found in Alzheimer's disease.

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12 December 2020

Complete and long-term rescue of lesioned adult motoneurons by lentiviral-mediated expression of glial cell line-derived neurotrophic factor in the facial nucleus.

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12 December 2020

Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work

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12 December 2020

Structure, microtubule interactions, and paired helical filament aggregation by tau mutants of frontotemporal dementias

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12 December 2020

Mutations of tau protein in frontotemporal dementia promote aggregation of paired helical filaments by enhancing local beta-structure

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12 December 2020

Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease.

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12 December 2020

Phosphorylated serine 199 of microtubule-associated protein tau is a neuronal epitope abundantly expressed in youth and an early marker of tau pathology

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12 December 2020

Tangle and neuron numbers, but not amyloid load, predict cognitive status in Alzheimer’s disease

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12 December 2020

Staging of argyrophilic grains: an age-associated tauopathy

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12 December 2020

Tau aggregation is driven by a transition from random coil to beta sheet structure

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12 December 2020

Epitope mapping of mAbs AT8 and Tau5 directed against hyperphosphorylated regions of the human tau protein

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12 December 2020

Pathological tau burden and distribution distinguishes progressive supranuclear palsy-parkinsonism from Richardson's syndrome.

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12 December 2020

Fibrillogenic nuclei composed of P301L mutant tau induce elongation of P301L tau but not wild-type tau

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12 December 2020

The potential for beta-structure in the repeat domain of tau protein determines aggregation, synaptic decay, neuronal loss, and coassembly with endogenous Tau in inducible mouse models of tauopathy.

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12 December 2020

Proline-directed pseudo-phosphorylation at AT8 and PHF1 epitopes induces a compaction of the paperclip folding of Tau and generates a pathological (MC-1) conformation

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12 December 2020

Pathogenic missense MAPT mutations differentially modulate tau aggregation propensity at nucleation and extension steps

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12 December 2020

Conformational diversity of wild-type Tau fibrils specified by templated conformation change

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12 December 2020

Transmission and spreading of tauopathy in transgenic mouse brain

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12 December 2020

Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration

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12 December 2020

Novel diffusion barrier for axonal retention of Tau in neurons and its failure in neurodegeneration

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12 December 2020

Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease

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12 December 2020

Proteostasis of tau. Tau overexpression results in its secretion via membrane vesicles.

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12 December 2020

Trans-synaptic spread of tau pathology in vivo

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12 December 2020

Propagation of tau pathology in a model of early Alzheimer's disease

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12 December 2020

Paired helical filaments from Alzheimer disease brain induce intracellular accumulation of Tau protein in aggresomes

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12 December 2020

Hyperphosphorylation and cleavage at D421 enhance tau secretion

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12 December 2020

Constitutive secretion of tau protein by an unconventional mechanism.

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12 December 2020

Clinical, neuropathological, and biochemical characterization of the novel tau mutation P332S.

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12 December 2020

Extracellular Tau levels are influenced by variability in Tau that is associated with tauopathies

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12 December 2020

Physiological release of endogenous tau is stimulated by neuronal activity.

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12 December 2020

Lentiviral delivery of the human wild-type tau protein mediates a slow and progressive neurodegenerative tau pathology in the rat brain

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12 December 2020

The importance of tau phosphorylation for neurodegenerative diseases

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12 December 2020

Soluble pathological tau in the entorhinal cortex leads to presynaptic deficits in an early Alzheimer's disease model

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12 December 2020

Neuron-to-neuron wild-type Tau protein transfer through a trans-synaptic mechanism: relevance to sporadic tauopathies

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12 December 2020

A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity

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12 December 2020

Neuronal activity regulates extracellular tau in vivo

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12 December 2020

Distinct tau prion strains propagate in cells and mice and define different tauopathies

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12 December 2020

Ectosomes: a new mechanism for non-exosomal secretion of tau protein

1 reference

12 December 2020

Starvation and inhibition of lysosomal function increased tau secretion by primary cortical neurons

1 reference

12 December 2020

Proteopathic tau seeding predicts tauopathy in vivo.

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12 December 2020

Conformation determines the seeding potencies of native and recombinant Tau aggregates

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12 December 2020

Invited review: Animal models of tauopathies and their implications for research/translation into the clinic

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12 December 2020

Invited review: Neuropathology of tauopathies: principles and practice.

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12 December 2020

Tau monoclonal antibody generation based on humanized yeast models: impact on Tau oligomerization and diagnostics

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12 December 2020

Invited review: Frontotemporal dementia caused by microtubule-associated protein tau gene (MAPT) mutations: a chameleon for neuropathology and neuroimaging

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12 December 2020

mTor mediates tau localization and secretion: Implication for Alzheimer's disease

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12 December 2020

Templated misfolding of Tau by prion-like seeding along neuronal connections impairs neuronal network function and associated behavioral outcomes in Tau transgenic mice

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12 December 2020

Tau pathology spread in PS19 tau transgenic mice following locus coeruleus (LC) injections of synthetic tau fibrils is determined by the LC's afferent and efferent connections

1 reference

12 December 2020

Deep clinical and neuropathological phenotyping of Pick disease

1 reference

12 December 2020

Tau Protein Hyperphosphorylation and Aggregation in Alzheimer's Disease and Other Tauopathies, and Possible Neuroprotective Strategies

1 reference

12 December 2020

Epitope mapping and structural basis for the recognition of phosphorylated tau by the anti-tau antibody AT8

1 reference

12 December 2020

The amyloid hypothesis of Alzheimer's disease at 25 years

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12 December 2020

The ordered assembly of tau is the gain-of-toxic function that causes human tauopathies

1 reference

12 December 2020

Tunneling nanotube (TNT)-mediated neuron-to neuron transfer of pathological Tau protein assemblies

1 reference

12 December 2020

What is the evidence that tau pathology spreads through prion-like propagation?

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12 December 2020

Unconventional Secretion Mediates the Trans-cellular Spreading of Tau

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12 December 2020

Reply: Will FTLD-tau work for all when FTDP-17 retires?

1 reference

12 December 2020

Inert and seed-competent tau monomers suggest structural origins of aggregation.

1 reference

12 December 2020