(Q60487632)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30613818%20AND%20SRC:MED&resulttype=core&format=json

17 April 2020

title

Hydroxychloroquine Inhibits Zika Virus NS2B-NS3 Protease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30613818%20AND%20SRC:MED&resulttype=core&format=json

17 April 2020

0 references

1 reference

5

1 reference

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17 April 2020

Rajanish Giri

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30613818%20AND%20SRC:MED&resulttype=core&format=json

17 April 2020

author name string

Ankur Kumar

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30613818%20AND%20SRC:MED&resulttype=core&format=json

17 April 2020

Brooke Liang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30613818%20AND%20SRC:MED&resulttype=core&format=json

17 April 2020

Murali Aarthy

3

1 reference

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17 April 2020

Sanjeev Kumar Singh

4

1 reference

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17 April 2020

Indira U Mysorekar

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30613818%20AND%20SRC:MED&resulttype=core&format=json

17 April 2020

language of work or name

English

0 references

publication date

24 December 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30613818%20AND%20SRC:MED&resulttype=core&format=json

17 April 2020

number of pages

10

1 reference

inferred from page(s)

published in

ACS Omega

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30613818%20AND%20SRC:MED&resulttype=core&format=json

17 April 2020

volume

3

1 reference

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17 April 2020

issue

12

1 reference

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17 April 2020

page(s)

18132-18141

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30613818%20AND%20SRC:MED&resulttype=core&format=json

on focus list of Wikimedia project

17 April 2020

WikiProject Zika Corpus

0 references

cites work

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Activity of recombinant dengue 2 virus NS3 protease in the presence of a truncated NS2B co-factor, small peptide substrates, and inhibitors.

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12 December 2020

Safety of hydroxychloroquine in pregnant patients with connective tissue diseases: A study of one hundred thirty‐three cases compared with a control group

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12 December 2020

Drug repositioning: identifying and developing new uses for existing drugs

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12 December 2020

Follow-up of infants exposed to hydroxychloroquine given to mothers during pregnancy and lactation

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12 December 2020

Structural basis for the activation of flaviviral NS3 proteases from dengue and West Nile virus.

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12 December 2020

Genetic and serologic properties of Zika virus associated with an epidemic, Yap State, Micronesia, 2007

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12 December 2020

Structure of West Nile virus NS3 protease: ligand stabilization of the catalytic conformation

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12 December 2020

Systematic review of hydroxychloroquine use in pregnant patients with autoimmune diseases

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12 December 2020

Structure and functionality in flavivirus NS-proteins: perspectives for drug design

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12 December 2020

Novel dengue virus-specific NS2B/NS3 protease inhibitor, BP2109, discovered by a high-throughput screening assay

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12 December 2020

Structural and functional parameters of the flaviviral protease: a promising antiviral drug target

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12 December 2020

Ligand-Bound Structures of the Dengue Virus Protease Reveal the Active Conformation

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12 December 2020

Biomolecular simulation: a computational microscope for molecular biology

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12 December 2020

A folding-after-binding mechanism describes the recognition between the transactivation domain of c-Myb and the KIX domain of the CREB-binding protein

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12 December 2020

Development and characterization of new peptidomimetic inhibitors of the West Nile virus NS2B-NS3 protease

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12 December 2020

Structure of the transition state for the binding of c-Myb and KIX highlights an unexpected order for a disordered system

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12 December 2020

A novel dengue virus inhibitor, BP13944, discovered by high-throughput screening with dengue virus replicon cells selects for resistance in the viral NS2B/NS3 protease

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DrugBank 4.0: shedding new light on drug metabolism

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12 December 2020

The flavivirus protease as a target for drug discovery

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12 December 2020

Zika virus infection complicated by Guillain-Barre syndrome--case report, French Polynesia, December 2013

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12 December 2020

The mechanism of binding of the KIX domain to the mixed lineage leukemia protein and its allosteric role in the recognition of c-Myb

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12 December 2020

Biochemistry and medicinal chemistry of the dengue virus protease

1 reference

12 December 2020

Hydroxychloroquine-inhibited dengue virus is associated with host defense machinery

1 reference

12 December 2020

Novel dengue virus NS2B/NS3 protease inhibitors

1 reference

12 December 2020

Concern over Zika virus grips the world

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12 December 2020

Zika Virus Associated with Microcephaly

1 reference

12 December 2020

Molecular Recognition by Templated Folding of an Intrinsically Disordered Protein

1 reference

12 December 2020

Guillain-Barré Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study

1 reference

12 December 2020

CNS infections: Zika virus infection could trigger Guillain–Barré syndrome

1 reference

12 December 2020

The 3.8 Å resolution cryo-EM structure of Zika virus

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12 December 2020

Towards understanding the unbound state of drug compounds: Implications for the intramolecular reorganization energy upon binding.

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12 December 2020

Zika Virus and Birth Defects — Reviewing the Evidence for Causality

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12 December 2020

Open drug discovery for the Zika virus

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12 December 2020

Zika Virus Infection during Pregnancy in Mice Causes Placental Damage and Fetal Demise

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12 December 2020

Crystal structure of Zika virus NS2B-NS3 protease in complex with a boronate inhibitor

1 reference

12 December 2020

Molecular modeling and structural analysis of nAChR variants uncovers the mechanism of resistance to snake toxins.

1 reference

12 December 2020

Non-vector-borne transmission of Zika virus: A systematic review

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12 December 2020

Epidemiologic investigation of a family cluster of imported ZIKV cases in Guangdong, China: probable human-to-human transmission

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12 December 2020

Substrate profiling of Zika virus NS2B-NS3 protease.

1 reference

12 December 2020

Investigating the folding pathway and substrate induced conformational changes in B. malayi Guanylate kinase.

1 reference

12 December 2020

Mechanisms of activation and inhibition of Zika virus NS2B-NS3 protease

1 reference

12 December 2020

Intrinsically Disordered Side of the Zika Virus Proteome

1 reference

12 December 2020

Chloroquine, an Endocytosis Blocking Agent, Inhibits Zika Virus Infection in Different Cell Models

1 reference

12 December 2020

Peptide-Boronic Acid Inhibitors of Flaviviral Proteases: Medicinal Chemistry and Structural Biology

1 reference

12 December 2020

Identification of novel small molecule inhibitors against NS2B/NS3 serine protease from Zika virus

1 reference

12 December 2020

Extended substrate specificity and first potent irreversible inhibitor/activity-based probe design for Zika virus NS2B-NS3 protease

1 reference

12 December 2020

Delineating the role of ionic interactions in structural and functional integrity of B. malayi Guanylate kinase.

1 reference

12 December 2020

Novel antiviral activity and mechanism of bromocriptine as a Zika virus NS2B-NS3 protease inhibitor

1 reference

12 December 2020

Dengue Virus NS2B/NS3 Protease Inhibitors Exploiting the Prime Side

1 reference

12 December 2020

Effects of NS2B-NS3 protease and furin inhibition on West Nile and Dengue virus replication

1 reference

12 December 2020

Epigallocatechin gallate, an active green tea compound inhibits the Zika virus entry into host cells via binding the envelope protein.

1 reference

12 December 2020

Existing drugs as broad-spectrum and potent inhibitors for Zika virus by targeting NS2B-NS3 interaction

1 reference

12 December 2020

Inhibition of autophagy limits vertical transmission of Zika virus in pregnant mice

1 reference

12 December 2020

Molecular Recognition Features in Zika Virus Proteome.

1 reference

12 December 2020

Predicting Binding Affinities for GPCR Ligands Using Free-Energy Perturbation

1 reference

12 December 2020

Identifiers

DOI

10.1021/ACSOMEGA.8B01002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30613818%20AND%20SRC:MED&resulttype=core&format=json

17 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30613818%20AND%20SRC:MED&resulttype=core&format=json

17 April 2020

PubMed publication ID

30613818

1 reference