(Q60907168)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30530698%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

title

Nuclear receptor HNF4A transrepresses CLOCK:BMAL1 and modulates tissue-specific circadian networks (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30530698%20AND%20SRC:MED&resulttype=core&format=json

Hepatocyte nuclear factor 4 alpha

13 April 2020

main subject

1 reference

negative regulation of transcription, DNA-templated

GOA release 2020-03-11

1 reference

Hepatic nuclear factor 4, alpha

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Tsuyoshi Hirota

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30530698%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

Steve A. Kay

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30530698%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

author name string

Meng Qu

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30530698%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

Tomas Duffy

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30530698%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

language of work or name

English

0 references

publication date

10 December 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30530698%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

13 April 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30530698%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

volume

115

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30530698%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

issue

52

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30530698%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

page(s)

E12305-E12312

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30530698%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International

13 April 2020

copyright license

start time

10 December 2018

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Transcriptional interference between c-Jun and the glucocorticoid receptor: mutual inhibition of DNA binding due to direct protein-protein interaction.

1 reference

12 December 2020

Negative cross-talk between RelA and the glucocorticoid receptor: a possible mechanism for the antiinflammatory action of glucocorticoids

1 reference

12 December 2020

Identification and characterization of a putative bile acid-responsive element in cholesterol 7 alpha-hydroxylase gene promoter

1 reference

12 December 2020

A distinct modulating domain in glucocorticoid receptor monomers in the repression of activity of the transcription factor AP-1.

1 reference

12 December 2020

Physical association and functional antagonism between the p65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor

1 reference

12 December 2020

Functional domains of the nuclear receptor hepatocyte nuclear factor 4.

1 reference

12 December 2020

Positional cloning of the mouse circadian clock gene

1 reference

12 December 2020

The maturity-onset diabetes of the young (MODY1) transcription factor HNF4alpha regulates expression of genes required for glucose transport and metabolism

1 reference

12 December 2020

Role of the CLOCK protein in the mammalian circadian mechanism

1 reference

12 December 2020

SRC-1 and GRIP1 coactivate transcription with hepatocyte nuclear factor 4.

1 reference

12 December 2020

mCRY1 and mCRY2 are essential components of the negative limb of the circadian clock feedback loop

1 reference

12 December 2020

Modulation of transcriptional activation and coactivator interaction by a splicing variation in the F domain of nuclear receptor hepatocyte nuclear factor 4alpha1.

1 reference

12 December 2020

Light-independent role of CRY1 and CRY2 in the mammalian circadian clock.

1 reference

12 December 2020

HNF4 and COUP-TFII interact to modulate transcription of the cholesterol 7alpha-hydroxylase gene (CYP7A1).

1 reference

12 December 2020

Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha.

1 reference

12 December 2020

Analysis of protein dimerization and ligand binding of orphan receptor HNF4alpha

1 reference

12 December 2020

Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis

1 reference

12 December 2020

Mop3 is an essential component of the master circadian pacemaker in mammals

1 reference

12 December 2020

Nonredundant roles of the mPer1 and mPer2 genes in the mammalian circadian clock

1 reference

12 December 2020

Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

1 reference

12 December 2020

Nuclear receptors and lipid physiology: opening the X-files

1 reference

12 December 2020

Expression of HNF4alpha isoforms in mouse liver development is regulated by sequential promoter usage and constitutive 3' end splicing

1 reference

12 December 2020

Posttranslational mechanisms regulate the mammalian circadian clock

1 reference

12 December 2020

Extensive and divergent circadian gene expression in liver and heart

1 reference

12 December 2020

Coordinated transcription of key pathways in the mouse by the circadian clock

1 reference

12 December 2020

The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator

1 reference

12 December 2020

Dec1 and Dec2 are regulators of the mammalian molecular clock

1 reference

12 December 2020

Hepatocyte nuclear factor 1 alpha: a key mediator of the effect of bile acids on gene expression

1 reference

12 December 2020

Role of the hepatocyte nuclear factor 4alpha in control of the pregnane X receptor during fetal liver development

1 reference

12 December 2020

Hepatocyte Nuclear Factor 4α Is a Central Regulator of Bile Acid Conjugation

1 reference

12 December 2020

PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues

1 reference

12 December 2020

Control of pancreas and liver gene expression by HNF transcription factors

1 reference

12 December 2020

A functional genomics strategy reveals Rora as a component of the mammalian circadian clock

1 reference

12 December 2020

Glucocorticoid Ligands Specify Different Interactions with NF-κB by Allosteric Effects on the Glucocorticoid Receptor DNA Binding Domain

1 reference

12 December 2020

BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis

1 reference

12 December 2020

Finding new clock components: past and future.

1 reference

12 December 2020

The orphan nuclear receptor RORalpha regulates circadian transcription of the mammalian core-clock Bmal1

1 reference

12 December 2020

Obesity and metabolic syndrome in circadian Clock mutant mice

1 reference

12 December 2020

HNF4alpha reduces proliferation of kidney cells and affects genes deregulated in renal cell carcinoma

1 reference

12 December 2020

Dysregulated expression of P1 and P2 promoter-driven hepatocyte nuclear factor-4alpha in the pathogenesis of human cancer

1 reference

12 December 2020

Feedback repression is required for mammalian circadian clock function

1 reference

12 December 2020

In vivo role of the HNF4alpha AF-1 activation domain revealed by exon swapping

1 reference

12 December 2020

Hepatocyte nuclear factor 4alpha is essential for embryonic development of the mouse colon

1 reference

12 December 2020

Nuclear receptor expression links the circadian clock to metabolism

1 reference

12 December 2020

Cross-talk between nuclear receptors and nuclear factor kappaB.

1 reference

12 December 2020

Redundant function of REV-ERBalpha and beta and non-essential role for Bmal1 cycling in transcriptional regulation of intracellular circadian rhythms

1 reference

12 December 2020

A genome-wide RNAi screen for modifiers of the circadian clock in human cells

1 reference

12 December 2020

Loss of hepatocyte-nuclear-factor-4alpha affects colonic ion transport and causes chronic inflammation resembling inflammatory bowel disease in mice

1 reference

12 December 2020

Hepatocyte nuclear factor 4alpha coordinates a transcription factor network regulating hepatic fatty acid metabolism.

1 reference

12 December 2020

Integrated approach for the identification of human hepatocyte nuclear factor 4alpha target genes using protein binding microarrays

1 reference

12 December 2020

The mammalian clock component PERIOD2 coordinates circadian output by interaction with nuclear receptors

1 reference

12 December 2020

Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes

1 reference

12 December 2020

Developmental and tissue-specific regulation of hepatocyte nuclear factor 4-alpha (HNF4-alpha) isoforms in rodents

1 reference

12 December 2020

Genome-wide profiling of the core clock protein BMAL1 targets reveals a strict relationship with metabolism

1 reference

12 December 2020

Genome-wide and phase-specific DNA-binding rhythms of BMAL1 control circadian output functions in mouse liver

1 reference

12 December 2020

Cryptochromes mediate rhythmic repression of the glucocorticoid receptor

1 reference

12 December 2020

Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β

1 reference

12 December 2020

Rev-erbα and Rev-erbβ coordinately protect the circadian clock and normal metabolic function

1 reference

12 December 2020

RORγ directly regulates the circadian expression of clock genes and downstream targets in vivo

1 reference

12 December 2020

Transcriptional architecture and chromatin landscape of the core circadian clock in mammals

1 reference

12 December 2020

CircaDB: a database of mammalian circadian gene expression profiles

1 reference

12 December 2020

The five Rs of glucocorticoid action during inflammation: ready, reinforce, repress, resolve, and restore.

1 reference

12 December 2020

Circadian clocks and neurodegenerative diseases: time to aggregate?

1 reference

12 December 2020

Modulation of glucocorticoid receptor induction properties by core circadian clock proteins

1 reference

12 December 2020

CLOCK:BMAL1 is a pioneer-like transcription factor

1 reference

12 December 2020

Nuclear Receptors, RXR, and the Big Bang

1 reference

12 December 2020

Cell type-specific functions of period genes revealed by novel adipocyte and hepatocyte circadian clock models

1 reference

12 December 2020

A novel protein, CHRONO, functions as a core component of the mammalian circadian clock

1 reference

12 December 2020

Machine learning helps identify CHRONO as a circadian clock component

1 reference

12 December 2020

A circadian gene expression atlas in mammals: implications for biology and medicine

1 reference

12 December 2020

Recent advances in circadian rhythms in cardiovascular system

1 reference

12 December 2020

Cancer/Testis Antigen PASD1 Silences the Circadian Clock

1 reference

12 December 2020

Cryptochrome 1 regulates the circadian clock through dynamic interactions with the BMAL1 C terminus

1 reference

12 December 2020

GENE REGULATION. Discrete functions of nuclear receptor Rev-erbα couple metabolism to the clock.

1 reference

12 December 2020

Circadian Amplitude Regulation via FBXW7-Targeted REV-ERBα Degradation

1 reference

12 December 2020

HNF6 and Rev-erbα integrate hepatic lipid metabolism by overlapping and distinct transcriptional mechanisms

1 reference

12 December 2020

Nuclear Proteomics Uncovers Diurnal Regulatory Landscapes in Mouse Liver.

1 reference

12 December 2020

Formation of a repressive complex in the mammalian circadian clock is mediated by the secondary pocket of CRY1.

1 reference

12 December 2020

Immune regulation by glucocorticoids.

1 reference

12 December 2020

Circadian repressors CRY1 and CRY2 broadly interact with nuclear receptors and modulate transcriptional activity.

1 reference

12 December 2020

Transcription factor activity rhythms and tissue-specific chromatin interactions explain circadian gene expression across organs.

1 reference

12 December 2020

Rev-erbα dynamically modulates chromatin looping to control circadian gene transcription.

1 reference

12 December 2020

An evolutionary hotspot defines functional differences between CRYPTOCHROMES.

1 reference

12 December 2020

A database of tissue-specific rhythmically expressed human genes has potential applications in circadian medicine

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1816411115

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30530698%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30530698%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

PubMed publication ID

30530698

1 reference