(Q61197456)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24770399%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

title

Emi2 mediates meiotic MII arrest by competitively inhibiting the binding of Ube2S to the APC/C (English)

1 reference

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16 March 2020

author name string

Kosuke Sako

1

1 reference

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16 March 2020

Kazuhiro Suzuki

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24770399%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

Michitaka Isoda

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24770399%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

Satomi Yoshikai

4

1 reference

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16 March 2020

Chiharu Senoo

5

1 reference

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16 March 2020

Nobushige Nakajo

6

1 reference

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16 March 2020

Munemichi Ohe

7

1 reference

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16 March 2020

Noriyuki Sagata

8

1 reference

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16 March 2020

language of work or name

English

0 references

publication date

28 April 2014

1 reference

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16 March 2020

published in

Nature Communications

1 reference

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16 March 2020

volume

5

1 reference

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16 March 2020

issue

1

0 references

page(s)

3667

1 reference

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https://scigraph.springernature.com/pub.10.1038/ncomms4667

16 March 2020

exact match

0 references

cites work

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Meiotic metaphase arrest in animal oocytes: its mechanisms and biological significance.

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The anaphase promoting complex/cyclosome: a machine designed to destroy

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Under arrest: cytostatic factor (CSF)-mediated metaphase arrest in vertebrate eggs

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Xenopus polo-like kinase Plx1 regulates XErp1, a novel inhibitor of APC/C activity

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7 January 2021

Mammalian Emi2 mediates cytostatic arrest and transduces the signal for meiotic exit via Cdc20.

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7 January 2021

A role for the anaphase-promoting complex inhibitor Emi2/XErp1, a homolog of early mitotic inhibitor 1, in cytostatic factor arrest of Xenopus eggs

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7 January 2021

A direct link of the Mos-MAPK pathway to Erp1/Emi2 in meiotic arrest of Xenopus laevis eggs.

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7 January 2021

Phosphorylation of Erp1 by p90rsk is required for cytostatic factor arrest in Xenopus laevis eggs.

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The anaphase-promoting complex/cyclosome inhibitor Emi2 is essential for meiotic but not mitotic cell cycles.

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7 January 2021

Mouse Emi2 is required to enter meiosis II by reestablishing cyclin B1 during interkinesis

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7 January 2021

The c-mos proto-oncogene product is a cytostatic factor responsible for meiotic arrest in vertebrate eggs

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7 January 2021

Cytostatic factor: an activity that puts the cell cycle on hold

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7 January 2021

CaMKII and polo-like kinase 1 sequentially phosphorylate the cytostatic factor Emi2/XErp1 to trigger its destruction and meiotic exit

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7 January 2021

Calcium triggers exit from meiosis II by targeting the APC/C inhibitor XErp1 for degradation

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7 January 2021

Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor

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7 January 2021

Emi2-mediated inhibition of E2-substrate ubiquitin transfer by the anaphase-promoting complex/cyclosome through a D-box-independent mechanism

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7 January 2021

Emi2 inhibition of the anaphase-promoting complex/cyclosome absolutely requires Emi2 binding via the C-terminal RL tail

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7 January 2021

Dynamic regulation of Emi2 by Emi2-bound Cdk1/Plk1/CK1 and PP2A-B56 in meiotic arrest of Xenopus eggs

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7 January 2021

Control of Emi2 activity and stability through Mos-mediated recruitment of PP2A.

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7 January 2021

Structural insights into anaphase-promoting complex function and mechanism

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7 January 2021

Cubism and the cell cycle: the many faces of the APC/C.

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7 January 2021

Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex

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7 January 2021

The unique N terminus of the UbcH10 E2 enzyme controls the threshold for APC activation and enhances checkpoint regulation of the APC.

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7 January 2021

UBE2S elongates ubiquitin chains on APC/C substrates to promote mitotic exit

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7 January 2021

Identification of a physiological E2 module for the human anaphase-promoting complex

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7 January 2021

UBE2S drives elongation of K11-linked ubiquitin chains by the anaphase-promoting complex

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7 January 2021

K11-linked polyubiquitination in cell cycle control revealed by a K11 linkage-specific antibody

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7 January 2021

APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1

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7 January 2021

Emi1 preferentially inhibits ubiquitin chain elongation by the anaphase-promoting complex

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7 January 2021

Processive ubiquitin chain formation by the anaphase-promoting complex.

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7 January 2021

A role for Cdc2- and PP2A-mediated regulation of Emi2 in the maintenance of CSF arrest.

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7 January 2021

Cell cycle-regulated recognition of the destruction box of cyclin B by the APC/C in Xenopus egg extracts

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7 January 2021

Pharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damage

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7 January 2021

An APC/C inhibitor stabilizes cyclin B1 by prematurely terminating ubiquitination

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7 January 2021

Cdc20: a WD40 activator for a cell cycle degradation machine

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7 January 2021

Substrate binding on the APC/C occurs between the coactivator Cdh1 and the processivity factor Doc1.

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7 January 2021

The mechanism of linkage-specific ubiquitin chain elongation by a single-subunit E2

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7 January 2021

Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex

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7 January 2021

Rapid E2-E3 assembly and disassembly enable processive ubiquitylation of cullin-RING ubiquitin ligase substrates

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7 January 2021

Electron microscopy structure of human APC/CCDH1–EMI1 reveals multimodal mechanism of E3 ligase shutdown

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7 January 2021

Structures of APC/C(Cdh1) with substrates identify Cdh1 and Apc10 as the D-box co-receptor

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7 January 2021

Doc1 mediates the activity of the anaphase-promoting complex by contributing to substrate recognition.

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7 January 2021

The Doc1 subunit is a processivity factor for the anaphase-promoting complex.

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7 January 2021

The APC subunit Doc1 promotes recognition of the substrate destruction box.

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7 January 2021

Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase

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7 January 2021

Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome

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7 January 2021

Nek2B, a novel maternal form of Nek2 kinase, is essential for the assembly or maintenance of centrosomes in early Xenopus embryos

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7 January 2021

Erp1/Emi2 is essential for the meiosis I to meiosis II transition in Xenopus oocytes

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7 January 2021