(Q61450807)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30617067%20AND%20SRC:MED&resulttype=core&format=json

17 April 2020

title

AWZ1066S, a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis (English)

1 reference

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17 April 2020

1 reference

4

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17 April 2020

Rachel H Clare

6

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17 April 2020

John Archer

16

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17 April 2020

Alexandra Ehrens

19

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17 April 2020

Marc P Hübner

20

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17 April 2020

Adam P Roberts

22

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17 April 2020

Alasdair T M Hubbard

23

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17 April 2020

Edward W. Tate

24

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17 April 2020

Remigiusz A Serwa

25

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17 April 2020

Joseph D Turner

31

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17 April 2020

Mark J. Taylor

32

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17 April 2020

Steve Ward

33

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17 April 2020

30

Janet Hemingway

1 reference

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17 April 2020

9

Amy Siu

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17 April 2020

author name string

W David Hong

1

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17 April 2020

Farid Benayoud

2

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17 April 2020

Gemma L Nixon

3

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17 April 2020

Kelly L Johnston

5

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17 April 2020

Andrew Cassidy

7

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17 April 2020

Darren A N Cook

8

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17 April 2020

Motohiro Shiotani

10

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17 April 2020

Peter J H Webborn

11

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17 April 2020

Stefan Kavanagh

12

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17 April 2020

Ghaith Aljayyoussi

13

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17 April 2020

Emma Murphy

14

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17 April 2020

Andrew Steven

15

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17 April 2020

Dominique Struever

17

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17 April 2020

Stefan J Frohberger

18

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17 April 2020

Suet C Leung

26

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17 April 2020

Li Qie

27

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17 April 2020

Neil G Berry

28

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17 April 2020

Fabian Gusovsky

29

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17 April 2020

Paul M O'Neill

34

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17 April 2020

Achim Hoerauf

21

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17 April 2020

language of work or name

English

0 references

publication date

7 January 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30617067%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

17 April 2020

published in

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17 April 2020

volume

116

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17 April 2020

issue

4

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17 April 2020

page(s)

1414-1419

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Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International

17 April 2020

copyright license

start time

7 January 2019

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Population dynamics of Wolbachia bacterial endosymbionts in Brugia malayi.

1 reference

12 December 2020

Macrofilaricidal activity after doxycycline treatment of Wuchereria bancrofti: a double-blind, randomised placebo-controlled trial

1 reference

12 December 2020

Wolbachia bacterial endosymbionts of filarial nematodes

1 reference

12 December 2020

A randomized, double-blind clinical trial of a 3-week course of doxycycline plus albendazole and ivermectin for the treatment of Wuchereria bancrofti infection.

1 reference

12 December 2020

Wolbachia endobacteria depletion by doxycycline as antifilarial therapy has macrofilaricidal activity in onchocerciasis: a randomized placebo-controlled study

1 reference

12 December 2020

Macrofilaricidal effect of 4 weeks of treatment with doxycycline on Wuchereria bancrofti

1 reference

12 December 2020

Litomosoides sigmodontis: a simple method to infect mice with L3 larvae obtained from the pleural space of recently infected jirds (Meriones unguiculatus).

1 reference

12 December 2020

Macrofilaricidal activity after doxycycline only treatment of Onchocerca volvulus in an area of Loa loa co-endemicity: a randomized controlled trial

1 reference

12 December 2020

Using an intravenous catheter to carry out abdominal lavage in the gerbil

1 reference

12 December 2020

Lymphatic filariasis and onchocerciasis

1 reference

12 December 2020

Elimination of lymphatic filariasis: do we have the drugs to complete the job?

1 reference

12 December 2020

Macrofilaricidal Activity in Wuchereria bancrofti after 2 Weeks Treatment with a Combination of Rifampicin plus Doxycycline

1 reference

12 December 2020

Elimination of onchocerciasis from Africa: possible?

1 reference

12 December 2020

Long term impact of large scale community-directed delivery of doxycycline for the treatment of onchocerciasis

1 reference

12 December 2020

Corallopyronin A specifically targets and depletes essential obligate Wolbachia endobacteria from filarial nematodes in vivo

1 reference

12 December 2020

Accurate detection of outliers and subpopulations with Pmetrics, a nonparametric and parametric pharmacometric modeling and simulation package for R

1 reference

12 December 2020

Reducing safety-related drug attrition: the use of in vitro pharmacological profiling.

1 reference

12 December 2020

Overcoming the challenges of drug discovery for neglected tropical diseases: the A·WOL experience

1 reference

12 December 2020

Optimization of pyrrolamide topoisomerase II inhibitors toward identification of an antibacterial clinical candidate (AZD5099).

1 reference

12 December 2020

Development and validation of a high-throughput anti-Wolbachia whole-cell screen: a route to macrofilaricidal drugs against onchocerciasis and lymphatic filariasis.

1 reference

12 December 2020

A murine macrofilaricide pre-clinical screening model for onchocerciasis and lymphatic filariasis

1 reference

12 December 2020

Repurposing of approved drugs from the human pharmacopoeia to target Wolbachia endosymbionts of onchocerciasis and lymphatic filariasis

1 reference

12 December 2020

Therapeutic efficacy and macrofilaricidal activity of doxycycline for the treatment of river blindness

1 reference

12 December 2020

Minocycline as a re-purposed anti-Wolbachia macrofilaricide: superiority compared with doxycycline regimens in a murine infection model of human lymphatic filariasis.

1 reference

12 December 2020

Discovery of Second Generation Reversible Covalent DPP1 Inhibitors Leading to an Oxazepane Amidoacetonitrile Based Clinical Candidate (AZD7986).

1 reference

12 December 2020

NOD2 dependent neutrophil recruitment is required for early protective immune responses against infectious Litomosoides sigmodontis L3 larvae

1 reference

12 December 2020

Short-Course, High-Dose Rifampicin Achieves Wolbachia Depletion Predictive of Curative Outcomes in Preclinical Models of Lymphatic Filariasis and Onchocerciasis.

1 reference

12 December 2020

Identification and prioritization of novel anti-Wolbachia chemotypes from screening a 10,000-compound diversity library

1 reference

12 December 2020

Albendazole and antibiotics synergize to deliver short-course anti-Wolbachia curative treatments in preclinical models of filariasis.

1 reference

12 December 2020

Alternative treatment strategies to accelerate the elimination of onchocerciasis.

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1816585116

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30617067%20AND%20SRC:MED&resulttype=core&format=json

17 April 2020

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17 April 2020

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