(Q61480518)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12955224%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

review article

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title

RNA interference: from an ancient mechanism to a state of the art therapeutic application? (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12955224%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12955224%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

Ute Schepers

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12955224%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

author name string

Christoph Arenz

series ordinal

1

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Ute Schepers

series ordinal

2

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publication date

23 July 2003

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12955224%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

published in

The Science of Nature

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12955224%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

volume

90

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12955224%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

page(s)

345-359

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12955224%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12955224%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s00114-003-0441-4

7 November 2019

exact match

0 references

1 reference

12 December 2020

Functional anatomy of a dsRNA trigger: differential requirement for the two trigger strands in RNA interference.

1 reference

12 December 2020

Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways.

1 reference

12 December 2020

Purification and characterization of the Pac1 ribonuclease of Schizosaccharomyces pombe

1 reference

12 December 2020

Cre recombinase: the universal reagent for genome tailoring

1 reference

12 December 2020

The polo-like kinase PLK-1 is required for nuclear envelope breakdown and the completion of meiosis in Caenorhabditis elegans

1 reference

12 December 2020

RNAi in C. elegans: soaking in the genome sequence

1 reference

12 December 2020

Retroviral vectors designed for targeted expression of RNA polymerase III-driven transcripts: a comparative study

1 reference

12 December 2020

A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA

1 reference

12 December 2020

Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

1 reference

12 December 2020

Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells

1 reference

12 December 2020

Targeted disruption of gene function in Drosophila by RNA interference (RNA-i): a role for nautilus in embryonic somatic muscle formation

1 reference

12 December 2020

Enhancers of glp-1, a gene required for cell-signaling in Caenorhabditis elegans, define a set of genes required for germline development

1 reference

12 December 2020

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

1 reference

12 December 2020

A short primer on RNAi: RNA-directed RNA polymerase acts as a key catalyst

1 reference

12 December 2020

The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA

1 reference

12 December 2020

1 reference

12 December 2020

Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans

1 reference

12 December 2020

Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi

1 reference

12 December 2020

Technology evaluation: fomivirsen, Isis Pharmaceuticals Inc/CIBA vision

1 reference

12 December 2020

An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

1 reference

12 December 2020

Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing

1 reference

12 December 2020

Technical advance: potato virus X amplicon-mediated silencing of nuclear genes

1 reference

12 December 2020

RNAi: nature abhors a double-strand

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12 December 2020

Targeted mRNA degradation by double-stranded RNA in vitro

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12 December 2020

The amplicon-plus system for high-level expression of transgenes in plants

1 reference

12 December 2020

Strong host resistance targeted against a viral suppressor of the plant gene silencing defence mechanism

1 reference

12 December 2020

Evidence that processed small dsRNAs may mediate sequence-specific mRNA degradation during RNAi in Drosophila embryos.

1 reference

12 December 2020

Small interfering RNAs: a revolutionary tool for the analysis of gene function and gene therapy

1 reference

12 December 2020

DNA methylation and epigenetic inheritance in plants and filamentous fungi

1 reference

12 December 2020

The rde-1 gene, RNA interference, and transposon silencing in C. elegans

1 reference

12 December 2020

A natural classification of ribonucleases

1 reference

12 December 2020

A DNA vector-based RNAi technology to suppress gene expression in mammalian cells

1 reference

12 December 2020

Short interfering RNA confers intracellular antiviral immunity in human cells

1 reference

12 December 2020

RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells

1 reference

12 December 2020

1 reference

12 December 2020

par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed

1 reference

12 December 2020

U6 promoter-driven siRNAs with four uridine 3' overhangs efficiently suppress targeted gene expression in mammalian cells.

1 reference

12 December 2020

Argonaute2, a link between genetic and biochemical analyses of RNAi

1 reference

12 December 2020

RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals

1 reference

12 December 2020

RNAi in human cells: basic structural and functional features of small interfering RNA.

1 reference

12 December 2020

Specific interference with gene function by double-stranded RNA in early mouse development

1 reference

12 December 2020

Introduction of a Chimeric Chalcone Synthase Gene into Petunia Results in Reversible Co-Suppression of Homologous Genes in trans

1 reference

12 December 2020

Isolation of quelling-defective (qde) mutants impaired in posttranscriptional transgene-induced gene silencing in Neurospora crassa

1 reference

12 December 2020

Use of dsRNA-mediated genetic interference to demonstrate that frizzled and frizzled 2 act in the wingless pathway.

1 reference

12 December 2020

1 reference

12 December 2020

ATP requirements and small interfering RNA structure in the RNA interference pathway

1 reference

12 December 2020

Specific interference with gene expression induced by long, double-stranded RNA in mouse embryonal teratocarcinoma cell lines.

1 reference

12 December 2020

Molecular characterization of a mouse cDNA encoding Dicer, a ribonuclease III ortholog involved in RNA interference

1 reference

12 December 2020

Disruption of an RNA helicase/RNAse III gene in Arabidopsis causes unregulated cell division in floral meristems

1 reference

12 December 2020

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

1 reference

12 December 2020

RNAi in Dictyostelium: the role of RNA-directed RNA polymerases and double-stranded RNase

1 reference

12 December 2020

RNA helicase MUT-14-dependent gene silencing triggered in C. elegans by short antisense RNAs

1 reference

12 December 2020

Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells

1 reference

12 December 2020

Mouse models of Tay-Sachs and Sandhoff diseases differ in neurologic phenotype and ganglioside metabolism

1 reference

12 December 2020

Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate

1 reference

12 December 2020

Small interfering RNA and gene silencing in transgenic mice and rats

1 reference

12 December 2020

RNAi as random degradative PCR: siRNA primers convert mRNA into dsRNAs that are degraded to generate new siRNAs.

1 reference

12 December 2020

A microRNA in a multiple-turnover RNAi enzyme complex

1 reference

12 December 2020

Inhibition of human immunodeficiency virus type 1 expression by a hairpin ribozyme

1 reference

12 December 2020

A branched pathway for transgene-induced RNA silencing in plants

1 reference

12 December 2020

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

1 reference

12 December 2020

Post-transcriptional gene silencing in plants.

1 reference

12 December 2020

The double-stranded RNA-dependent protein kinase PKR: structure and function

1 reference

12 December 2020

RNA interference: listening to the sound of silence

1 reference

12 December 2020

Modulation of HIV-1 replication by RNA interference

1 reference

12 December 2020

Antisense-RNA regulation and RNA interference

1 reference

12 December 2020

On the role of RNA amplification in dsRNA-triggered gene silencing

1 reference

12 December 2020

Small RNAs correspond to centromere heterochromatic repeats

1 reference

12 December 2020

siRNA-directed inhibition of HIV-1 infection

1 reference

12 December 2020

Suppression of gene silencing: a general strategy used by diverse DNA and RNA viruses of plants

1 reference

12 December 2020

Arabidopsis SGS2 and SGS3 genes are required for posttranscriptional gene silencing and natural virus resistance

1 reference

12 December 2020

Crystallographic and modeling studies of RNase III suggest a mechanism for double-stranded RNA cleavage

1 reference

12 December 2020

Consistent gene silencing in transgenic plants expressing a replicating potato virus X RNA.

1 reference

12 December 2020

Two genetic circuits repress the Caenorhabditis elegans heterochronic gene lin-28 after translation initiation

1 reference

12 December 2020

Viral suppressors of RNA silencing

1 reference

12 December 2020

Single-stranded antisense siRNAs guide target RNA cleavage in RNAi

1 reference

12 December 2020

A system for stable expression of short interfering RNAs in mammalian cells

1 reference

12 December 2020

An RNA-dependent RNA polymerase gene in Arabidopsis is required for posttranscriptional gene silencing mediated by a transgene but not by a virus

1 reference

12 December 2020

Inhibition of SV40 replicon function by engineered antisense RNA transcribed by RNA polymerase III.

1 reference

12 December 2020

The role of target accessibility for antisense inhibition.

1 reference

12 December 2020

Large-scale analysis of gene function in Caenorhabditis elegans by high-throughput RNAi

1 reference

12 December 2020

Detailed characterization of the posttranscriptional gene-silencing-related small RNA in a GUS gene-silenced tobacco

1 reference

12 December 2020

Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

1 reference

12 December 2020

RNA interference in adult mice.

1 reference

12 December 2020

The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation

1 reference

12 December 2020

A species of small antisense RNA in posttranscriptional gene silencing in plants

1 reference

12 December 2020

PKR--a protein kinase regulated by double-stranded RNA.

1 reference

12 December 2020

Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP

1 reference

12 December 2020

SDE3 encodes an RNA helicase required for post-transcriptional gene silencing in Arabidopsis

1 reference

12 December 2020

Systemic acquired silencing: transgene-specific post-transcriptional silencing is transmitted by grafting from silenced stocks to non-silenced scions

1 reference

12 December 2020

The Sequence of the Human Genome

1 reference

12 December 2020

Effective expression of small interfering RNA in human cells

1 reference

12 December 2020

Domains in gene silencing and cell differentiation proteins: the novel PAZ domain and redefinition of the Piwi domain

1 reference

12 December 2020

Ribonuclease activity and RNA binding of recombinant human Dicer

1 reference

12 December 2020

Purification and properties of ribonuclease III from Escherichia coli.

1 reference

12 December 2020

Novel antisense and peptide nucleic acid strategies for controlling gene expression

1 reference

12 December 2020

RNA interference (RNA(i)) induction with various types of synthetic oligonucleotide duplexes in cultured human cells.

1 reference

12 December 2020

Gene silencing: RNA makes RNA makes no protein

1 reference

12 December 2020

Thirty-three years later, a glimpse at the ribonuclease III active site.

1 reference

12 December 2020

Characteristics of post-transcriptional gene silencing

1 reference

12 December 2020

RNA silencing: the genome's immune system

1 reference

12 December 2020

Comparative sequence analysis of ribonucleases HII, III, II PH and D

1 reference

12 December 2020

RNAi functions in cultured mammalian neurons

1 reference

12 December 2020

RETRACTED: Viral pathogenicity determinants are suppressors of transgene silencing in Nicotiana benthamiana

1 reference

12 December 2020

AIR-2: An Aurora/Ipl1-related protein kinase associated with chromosomes and midbody microtubules is required for polar body extrusion and cytokinesis in Caenorhabditis elegans embryos

1 reference

12 December 2020

RNA Interference: A New Way to Analyze Protein Function

1 reference

12 December 2020

Overexpression of TAR sequences renders cells resistant to human immunodeficiency virus replication

1 reference

12 December 2020

The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a DExH-box helicase to direct RNAi in C. elegans

1 reference

12 December 2020

Specific and potent RNA interference in terminally differentiated myotubes

1 reference

12 December 2020

Role for a bidentate ribonuclease in the initiation step of RNA interference

1 reference

12 December 2020

Gene silencing in Neurospora crassa requires a protein homologous to RNA-dependent RNA polymerase.

1 reference

12 December 2020

Initial sequencing and analysis of the human genome

1 reference

12 December 2020

Systematic functional analysis of the Caenorhabditis elegans genome using RNAi

1 reference

12 December 2020