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Inhibiting Drp1-mediated mitochondrial fission selectively prevents the release of cytochrome c during apoptosis
scientific article published on 02 March 2007
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17332775
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17332775%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 December 2019
title
Inhibiting Drp1-mediated mitochondrial fission selectively prevents the release of cytochrome c during apoptosis
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17332775
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17332775%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 December 2019
main subject
mitochondrion
1 reference
based on heuristic
inferred from title
mitochondrial fission
1 reference
based on heuristic
inferred from title
apoptotic process
1 reference
based on heuristic
inferred from title
author
Jérôme Estaquier
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17332775
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17332775%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 December 2019
author name string
Arnoult D
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17332775
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17332775%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 December 2019
publication date
2 March 2007
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17332775
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17332775%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 December 2019
published in
Cell Death & Differentiation
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17332775
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17332775%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 December 2019
volume
14
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17332775
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17332775%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 December 2019
issue
6
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17332775
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17332775%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 December 2019
page(s)
1086-1094
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17332775
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17332775%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 December 2019
exact match
https://scigraph.springernature.com/pub.10.1038/sj.cdd.4402107
0 references
cites work
Molecular mechanisms of caspase regulation during apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The pathophysiology of mitochondrial cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial fission in apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial morphology and dynamics in yeast and multicellular eukaryotes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
hFis1, a novel component of the mammalian mitochondrial fission machinery
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A human dynamin-related protein controls the distribution of mitochondria
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Release of OPA1 during apoptosis participates in the rapid and complete release of cytochrome c and subsequent mitochondrial fragmentation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutation spectrum and splicing variants in the OPA1 gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Temporal dissection of Bax-induced events leading to fission of the single mitochondrion in Trypanosoma brucei
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial fragmentation in apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Which came first, the cytochrome c release or the mitochondrial fission?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial fission and apoptosis: an ongoing trial.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein translocation into mitochondria: the role of TIM complexes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bax/Bak-dependent release of DDP/TIMM8a promotes Drp1-mediated mitochondrial fission and mitoptosis during programmed cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Simultaneous release of adenylate kinase and cytochrome c in cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Endoplasmic reticulum BIK initiates DRP1-regulated remodelling of mitochondrial cristae during apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fzo1, a protein involved in mitochondrial fusion, inhibits apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibiting the mitochondrial fission machinery does not prevent Bax/Bak-dependent apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Disruption of fusion results in mitochondrial heterogeneity and dysfunction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A distinct pathway remodels mitochondrial cristae and mobilizes cytochrome c during apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of mitochondrial morphology through proteolytic cleavage of OPA1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial Release of Pro-apoptotic Proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytochrome c release from mitochondria proceeds by a two-step process
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reactive oxygen species generated from the mitochondrial electron transport chain induce cytochrome c dissociation from beef-heart submitochondrial particles via cardiolipin peroxidation. Possible role in the apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role for CED-9 and Egl-1 as regulators of mitochondrial fission and fusion dynamics
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis induced by microinjection of cytochrome c is caspase-dependent and is inhibited by Bcl-2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial release of AIF and EndoG requires caspase activation downstream of Bax/Bak-mediated permeabilization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4402107
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.CDD.4402107
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17332775
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17332775%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 December 2019
PubMed publication ID
17332775
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17332775
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17332775%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 December 2019
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