(Q61623388)

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DNA vaccine encoding heat shock protein 60 co-linked to HPV16 E6 and E7 tumor antigens generates more potent immunotherapeutic effects than respective E6 or E7 tumor antigens

scientific article published on 01 October 2007

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8 January 2020

DNA vaccine encoding heat shock protein 60 co-linked to HPV16 E6 and E7 tumor antigens generates more potent immunotherapeutic effects than respective E6 or E7 tumor antigens (English)

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8 January 2020

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8 January 2020

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8 January 2020

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8 January 2020

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Chia-Yen Huang

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8 January 2020

Ming-Cheng Chang

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8 January 2020

Yi-Ning Su

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8 January 2020

Yi-Chun Lin

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8 January 2020

Chang-Yao Hsieh

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1 October 2007

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8 January 2020

Gynecologic Oncology

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8 January 2020

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8 January 2020

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8 January 2020

404-412

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8 January 2020

Exposing the immunology of naked DNA vaccines

1 reference

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Induction in humans of CD8+ and CD4+ T cell and antibody responses by sequential immunization with malaria DNA and recombinant protein

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IL-23 induces stronger sustained CTL and Th1 immune responses than IL-12 in hepatitis C virus envelope protein 2 DNA immunization

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Enhanced responses to a DNA vaccine encoding a fusion antigen that is directed to sites of immune induction

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DNA vaccines with single-chain Fv fused to fragment C of tetanus toxin induce protective immunity against lymphoma and myeloma

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Heat shock fusion proteins as vehicles for antigen delivery into the major histocompatibility complex class I presentation pathway

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Enhanced immunogenicity of heat shock protein 70 peptide complexes from dendritic cell-tumor fusion cells.

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Heat shock proteins come of age: primitive functions acquire new roles in an adaptive world

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7 January 2021

Heat shock protein--peptide complexes as immunotherapy for human cancer

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Enhanced T-cell immunity induced by dendritic cells with phagocytosis of heat shock protein 70 gene-transfected tumor cells in early phase of apoptosis

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Development of a DNA vaccine targeting human papillomavirus type 16 oncoprotein E6.

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Fusion protein vaccine by domains of bacterial exotoxin linked with a tumor antigen generates potent immunologic responses and antitumor effects.

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7 January 2021

Tumor-specific immunity and antiangiogenesis generated by a DNA vaccine encoding calreticulin linked to a tumor antigen

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Characterization of DNA vaccines encoding the domains of calreticulin for their ability to elicit tumor-specific immunity and antiangiogenesis

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Improving vaccine potency through intercellular spreading and enhanced MHC class I presentation of antigen.

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Identification of tyrosinase-related protein 2 as a tumor rejection antigen for the B16 melanoma

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Gene gun-mediated DNA vaccination induces antitumor immunity against human papillomavirus type 16 E7-expressing murine tumor metastases in the liver and lungs

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7 January 2021

Chimeric DNA vaccine reverses morphine-induced immunosuppression and tumorigenesis.

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Vaccination with cytotoxic T lymphocyte epitope-containing peptide protects against a tumor induced by human papillomavirus type 16-transformed cells

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Cancer immunotherapy using Sindbis virus replicon particles encoding a VP22-antigen fusion.

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Enhancement of Sindbis virus self-replicating RNA vaccine potency by linkage of Mycobacterium tuberculosis heat shock protein 70 gene to an antigen gene.

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Naked RNA vaccine controls tumors with down-regulated MHC class I expression through NK cells and perforin-dependent pathways.

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7 January 2021

Human heat shock protein 60 induces maturation of dendritic cells versus a Th1-promoting phenotype.

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7 January 2021

Predominant role for directly transfected dendritic cells in antigen presentation to CD8+ T cells after gene gun immunization.

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Heat shock proteins transfer peptides during antigen processing and CTL priming

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Receptor-mediated uptake of antigen/heat shock protein complexes results in major histocompatibility complex class I antigen presentation via two distinct processing pathways

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A mechanism for the specific immunogenicity of heat shock protein-chaperoned peptides

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Cutting edge: heat shock protein (HSP) 60 activates the innate immune response: CD14 is an essential receptor for HSP60 activation of mononuclear cells

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Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex

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Endocytosed HSP60s use toll-like receptor 2 (TLR2) and TLR4 to activate the toll/interleukin-1 receptor signaling pathway in innate immune cells

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Cytokine function of heat shock proteins

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CD91: a receptor for heat shock protein gp96

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Recombinant protein and DNA vaccines derived from hsp60 Trichophyton mentagrophytes control the clinical course of trichophytosis in bovine species and guinea-pigs

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Comparative analysis of antibody responses against HSP60, invariant surface glycoprotein 70, and variant surface glycoprotein reveals a complex antigen-specific pattern of immunoglobulin isotype switching during infection by Trypanosoma brucei

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Proteins and their derived peptides as carriers in a conjugate vaccine for Streptococcus pneumoniae: self-heat shock protein 60 and tetanus toxoid

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Self heat-shock protein (hsp60) peptide serves in a conjugate vaccine against a lethal pneumococcal infection.

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DNA Fragments of the Human 60-kDa Heat Shock Protein (HSP60) Vaccinate Against Adjuvant Arthritis: Identification of a Regulatory HSP60 Peptide

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Vaccination with empty plasmid DNA or CpG oligonucleotide inhibits diabetes in nonobese diabetic mice: modulation of spontaneous 60-kDa heat shock protein autoimmunity

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Mycobacterial heat-shock proteins as carrier molecules

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Competition inhibition of cytotoxic T-lymphocyte (CTL) lysis, a more sensitive method to identify candidate CTL epitopes than induction of antibody-detected MHC class I stabilization.

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Heat shock protein vaccines against cancer

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DNA immunization: ubiquitination of a viral protein enhances cytotoxic T-lymphocyte induction and antiviral protection but abrogates antibody induction

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based on heuristic

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10.1016/J.YGYNO.2007.06.031

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17905417%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17905417%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

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